Anti-inflammatory drug's potentially deadly side effect found to be rare
... may afford." A number of factors can affect the survival of patients with PML, but for now Clifford believes that developing a method to diagnose PML early in its development may be the best approach to averting future fatalities linked to natalizumab. "It takes two months or more for the drug's effects ...Researches discover gene critical for protection against septic-shock-induced death
... drug can minimize pathological damage and improve survival during sepsis caused by bacteria or viruses. Future studies will determine the therapeutic potential of targeting Nrf2 for treatment of sepsis and other inflammatory diseases that impact public health. ...Epidemic of unneeded amputations
... according to the CDC.--The CDC says the five-year survival rate for all lower extremity amputees is less than 50 percent. For diabetic amputees, the rate is less than 40 percent.--In a five-year study in medical journal Diabetes Care, 40 percent of diabetics and 29.8 percent of non-diabetics had a second amp...Malignant melanoma cells secrete protein required for embryo formation
...ne of the deadliest forms of cancer. The five-year survival rate for melanoma patients with widespread disease is between 7 percent and 19 percent. ...Progress being made in exploring potential use of stem cells to treat heart disease
...produce factors that are sufficient to invoke cell survival or repair responses in damaged heart cells "The use of stem cells to generate replacement cells for damaged heart muscle, valves, vessels and conduction cells holds great potential," says Srivastava, who is also a UCSF professor of pediatrics and...New potential drug target in tuberculosis
...al image of a protein that the bacterium needs for survival in human cells. This image reveals features of the molecule that could be targeted by new antibiotic drugs. The results appear in this week's online issue of the Proceedings of the National Academy of Sciences (PNAS). M. tuberculosis is dangerous be...Mosquito spray increases toxicity of pyrethroids in creek, study finds
...ray, the researchers compared the reproduction and survival rates of a species of water flea, Ceriodaphnia dub...11 water samples. Researchers also looked at the survival rates of a tiny, shrimp-like amphipod called Hyalella azteca, an indicator species for sediment toxi...Radioactive scorpion venom for fighting cancer
...mising signs for treating the tumor and prolonging survival rates for patients. At the Health Physics Society meeting this week in Providence, Rhode Island, Alan M. Jackson of the Henry Ford Health System in Detroit will report that he and his colleagues recently established safe procedures for the the...Survival of the selfless - scientists find cheats don't always prosper
Selfishness is not necessarily the best survival trait for microorganisms, according to researchers studying the comparative effectiveness of 'cheating' and 'cooperating' strains of yeast. Writing in the journal Nature today, the team reports that studies of lab-grown yeast populations suggest the...Genes discovered that allow gum disease bacterium to invade arteries
...t these four genes play a role in the invasion and survival of P. gingivalis inside artery cells," says Rodrigues. "The knowledge of how this pathogenic bacterium interacts with artery cells is important and may lead to the development of therapeutics and diagnostic tools for the detection and possibly preve...Microbes hitchhike across Atlantic on desert dust
...a. "This study presents evidence of early summer survival and transport of microorganisms from North Africa to a mid-Atlantic research site," says Dale Griffin of the U.S. Geological Survey in St. Petersburg, Florida, one of the researchers on the study. Griffin and his colleagues tested air samples on a r...Mass. General study finds potential ovarian cancer stem cells
... vast majority of patients, leading to a five-year survival rate of less than 30 percent. Those factors and other observations suggested that cancer stem cells may also be found with ovarian tumors, leading to the current study. The MGH researchers first examined two mouse ovarian cancer cell lines and id...Mouse mimics chronic leukemia, will aid drug development
...of viral, bacterial and fungal infections. Average survival after diagnosis is eight to 12 years. The standard treatment for CLL is the drug fludarabine, but the disease often becomes resistant to the drug. This TCL-1 mouse strain was originally developed by OSU cancer researcher Carlo M. Croce, professor ...Virus has 'catastrophic' affect on red squirrels, research shows
...e has been no outbreak. Until now the reds' main survival challenge was believed to be competition with grey squirrels over resources. However, this research highlights the urgency for new conservation strategies for the red squirrel, a species that has been in Britain for the last 10,000 years and is prot...Heart has enough oxygen to survive hypothermia, CPR crucial
... the study "Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?" The s...uence, oxygen supply was not a limiting factor for survival in the present experiments," the authors wrote. The rats in the one-hour group spontaneously norma...New egg freezing technique offers hope to hundreds of women
...on. Using this method, we achieved a more than 90% survival rate for the freeze-thawed oocytes and a high preg...een far less successful for oocytes. The post-thaw survival rate for human embryos is about 85-90%. Now, using the Cryotop method, we can achieve post-thaw surv...Life and death in the hippocampus: what young neurons need to survive
...e for Biological Studies pin-pointed the molecular survival gear required for a young neuron to successfully j...vity new neurons receive, which in turn determines survival or death." Combining mouse genetics and gene transfer techniques, Gage and a team headed by former...Study identifies new role for breast cancer susceptibility gene
...sed the gene for ANG1 from repression and promoted survival of neighboring blood vessel cells and formation of capillary-like structures. Further studies demonstrated that mouse mammary tumors deficient in BRCA1 display high levels of ANG1 expression, prominent vascularization, and accelerated growth. "Our...Researchers find cause of frontotemporal dementia
... not yet known, it may well be responsible for the survival of brain cells, because FTD patients have a shortage of this growth factor. The new finding predicts that progranulin might also play a role in other types of brain diseases in which brain cells die off ?such as Alzheimer's disease and Parkinson's di......hytridiomycosis, and other hazards threatening the survival of a third of all amphibian species around the world. "The scientific importance of the finding must motivate us to adopt urgent measures toward saving the last of these amphibians, both in the wild and through captive breeding programs," said Fabio...