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Tag: "survival" at biology news

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

... the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, accordi...rapy trial was designed to determine the effect on survival of the addition of locoregional radiation therapy (radiation to the lymph nodes and chest wall) to a...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

... the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, accordi...rapy trial was designed to determine the effect on survival of the addition of locoregional radiation therapy (radiation to the lymph nodes and chest wall) to a...

The secret to longevity in tubeworms

...9 years in a colony of 1,000 individuals; with it, survival increases to over 250 years, matching the longevity of actual living tubeworms. To date, the proposed return of sulfate to the sediments through the roots is only a hypothesis--albeit one with much to support it--that still awaits direct confirmatio...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...ary for far more DA neurons to surviveand for that survival to be long lasting in order to render thisapproach as a useful therapy in humans.Langston highlights that "clearly the study reported here will advanceresearch aimed at validating the use of stem cells to treatneurodegenerative disease" and this is m...

Scientists discover the cellular roots of graying hair

...eterminedthat the same pattern occurred.Since cell survival in general is influenced by an “anti-death?genecalled Bcl2, Fisher’s team analyzed mice lacking this gene. In adramatic fashion, the mice lost their melanocyte stem cells shortlyafter birth and quickly went gray. It may be that people who grayprematu...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...eterminedthat the same pattern occurred.Since cell survival in general is influenced by an “anti-death?genecalled Bcl2, Fisher’s team analyzed mice lacking this gene. In adramatic fashion, the mice lost their melanocyte stem cells shortlyafter birth and quickly went gray. It may be that people who grayprematu...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...eterminedthat the same pattern occurred.Since cell survival in general is influenced by an “anti-death?genecalled Bcl2, Fisher’s team analyzed mice lacking this gene. In adramatic fashion, the mice lost their melanocyte stem cells shortlyafter birth and quickly went gray. It may be that people who grayprematu...

U-M scientists find genes that control growth of common skin cancer

...inishing tumorsize, may not be curative due to the survival of this residual tumorcell population.“Our work demonstrates that BCC growth in this model remains strictlydependent on the Hh pathway,?says Mark Hutchin, M.D., a U-M residentin dermatology and lead author on the paper. This is different frommany oth...

Taking Aim With Nanoparticle PEBBLEs

...ma, PEBBLE-based treatment significantly increased survival time. People who get that type of cancer usually live less than four months without treatment; rats die within about five days. When Kopelman's group treated rats with PEBBLEs that weren't even tailored to home in on cancer cells, the rats lived twic...

Research Gives Hope For Liver Damage

...re for liver cirrhosisand a patient's only hope of survival is to receive a liver transplant.The Edinburgh scientists from the University's Centre for InflammationResearch, in collaboration with colleagues from the University ofSouthampton and Cincinnati, USA have, for the first time, identifiedtwo separate p...

The Bacteria's guide to survival

If there was a market for it, a survival guide for bacteria might include topics like "How ... jump ship, thus hurting the bacteria's chances of survival in the long run. Reporting in the open-access journal PLoS Biology, Magdalene So and colleagues pre...

Love at first smell

...h the correct mix of immune genes critical for the survival of future offspring. In the experiment females were fooled by the protein fragments into believing that males with insufficient MHC molecules would provide offspring with the ideal number of MHC types. However, when the perfume was added to males th...

In the migratory marathon, parasitized monarchs drop out early

It seems survival of the fittest affect every organism on Earth, even Monarch butterflies. Migratory Monarchs seem more resistant than non-migratory ones to parasite infections; scientists just uncovered why it is so. Explanation : infected monarchs quite don't make i...

Effective Cancer Treatments Follow The Clock

...t the body's internal biological clock affects the survival of immune cells that are targets of the anti-cancer drug cyclophosphamide (CY). “We became interested in examining this issue because there is a long history of knowledge that chemotherapeutic agents produce different mortality and morbidity at diff...

Viral protein influences key cell-signaling pathway

...nd destroys the immune system, HTLV-1 enhances the survival of T cells." But scientists don't understand how it prolongs T-cell survival and causes their proliferation. This study's findings offer some clues. It is the latest in a serie...

PGA on a tour under the skin

...ma-glutamate (PGA) to facilitate growth and ensure survival of the bacteria inside the human host. PGA protects the pathogen from innate host defenses during infection. S. epidermidis is the only human pathogen known to produce PGA other than Bacillus anthracis, but several differences exist in how the two pa...

Single stem cells from bone heal a broken heart

...iferative potential of cardiomyocytes and enhanced survival of host myocardium. This is the first report of endogenous cardiomyogenesis after adult human stem cell transplantation. Myocardial infarction and heart failure are associated with major morbidity and mortality and there are currently limited therap...

Researchers identify protein crucial for survival of Lyme-disease bacterium

.... "There must be subsets of genes important to its survival there. If it can't exist in ticks, it can't maintain itself in nature and hence can't infect animals or humans." UT Southwestern molecular microbiology graduate student Andrew Revel, a lead author of the study, found the bptA gene by screening a num...

Scientists identify molecule that regulates well-known tumor suppressor

...tively regulates PTEN function, and that this cell survival control mechanism is conserved among various tissues and species. Taken together, our data suggest that overexpression of DJ-1 can modulate PTEN tumor expression to the point where oncogenesis may result from upregulated PKB/Akt-mediated cell surviva...

Buying Time Through Hibernation on Demand

...dom instances of seemingly miraculous, unexplained survival in so-called clinically dead humans and our ability to induce ?and reverse ?metabolic quiescence in model organisms could have dramatic implications for medical care," Roth said. "In the end I suspect there will be clinical benefits and it will chang...

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