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Tag: "surrogate" at biology news

Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth

...yrene, a known potent mutagen and carcinogen, as a surrogate for total PAH exposure. Cruise emissions, cold engine emissions and intersection emissions were used to estimate total traffic PAH emissions. In addition, meteorological information was used in a geographic dispersion model to determine PAH exposure...

Microarrays as phenotype

...der of genes in a particular genome -- acting as a surrogate measure of cell physiology, said researchers at Ba...pes to determine the order of genes and are a good surrogate measure of cell status," said Dr. Gad Shaulsky, associate professor of molecular and human genetics ...

Russian 'surrogate' alcohols are a killer

...esearchers have now analyzed the contents of these surrogate alcohol products, finding either high alcohol cont..." For the current study, researchers analyzed the surrogate products being consumed, dividing them into three broad groups: "samogon" (home-produced spirits, al...

Phenolic compounds may explain Mediterranean diet benefits

...ta suggest that endothelial dysfunction could be a surrogate end point for prediction of cardiovascular risk, but we need more information on the utility of the different methods to evaluate endothelial dysfunction," Dr. Pérez Jiménez said. Robert F. Wilson, M.D., from the University of Minnesota in Minneapol...

Researchers use mass spectrometry to detect norovirus particles

...y separated, purified and concentrated a norovirus surrogate from a clinical sample within a few hours. Nanospray mass spectrometry was used to demonstrate the feasibility of detecting norovirus particles in the purified concentrates. Human norovirus is responsible for an estimated 23 million cases of gastroi...

Ancient ants arose 140-168 million years ago

...y separated, purified and concentrated a norovirus surrogate from a clinical sample within a few hours. Nanospray mass spectrometry was used to demonstrate the feasibility of detecting norovirus particles in the purified concentrates. Human norovirus is responsible for an estimated 23 million cases of gastroi...

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

...cribing how cigarette smoke condensate, which is a surrogate for cigarette smoke, can cause DNA damage and can block the DNA repair of a cell or compromise the DNA repair capacity of a cell. That can be detrimental for the cell and can lead to transformation or carcinogenesis." In their study, funded by the ...

Researchers report technique for freezing and preserving genetically enhanced pig embryos

... genetic material. After thawing and transfer to a surrogate mother, some of the embryos went on to produce liv...os are needed to produce a successful pregnancy in surrogate female pigs, this new procedure will enable workers to collect an adequate number of altered embryos...

Cloned mice created from fully differentiated cells, a milestone in cloning research

... copy. This cloned embryo is then implanted into a surrogate mother, and, if the process is successful, is carried to term. In their studies, the researchers compared the efficiency for cloning mice using a fully differentiated blood cell called a granulocyte with its ancestor cells at different stages: hema...

Improving outcomes in premature births

...alth outcome,?as the primary endpoint instead of a surrogate such as days gained or percent of births before 32 or 35 weeks of gestation."...

Plastic that degrades in seawater could be boon for cruise industry and others

...alth outcome,?as the primary endpoint instead of a surrogate such as days gained or percent of births before 32 or 35 weeks of gestation."...

Vitamins: Science doesn't always match policy

... In this quest, the development of more and better surrogate markers of adverse effects will be critical. Dose-response assessments of safety are badly needed for updating recommended safe and tolerable Upper Intake Levels," he says. Rosenberg also endorses a suggestion that multivitamins should be compose...

Plastic that grows on trees

... glucose and fructose and is viewed as a promising surrogate for petroleum-based chemicals. Glucose, in plant starch and cellulose, is nature’s most abundant sugar. “But getting a commercially viable yield of HMF from glucose has been very challenging,” Zhang said. “In addition to low yield until now, we al...

Penn researchers link cell's protein recycling systems

.... They use the fly eye, a neuron-rich tissue, as a surrogate for the brain because it is easy to visualize. They discovered that making the lysosomal system more or less active dramatically influenced the severity of neurodegeneration. “We found that whenever we knocked the lysosome system down, neurodegen...

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