New tool reveals secrets of migrating cells
...ls primed for combat with viral invaders. "We were surprised by how rapidly and directly the cells move to thei...er first use of two-photon imaging three years ago surprised her and many immunologists because it showed that thymocytes or immature T cells were highly mobile,...How monarch butterflies are wired for navigation
...r butterfly navigation. Also, the researchers were surprised to discover a key wiring connection between the li...l protocerebrum. Using tracer molecules, they were surprised to discover tiny neural fibers containing a key clock protein that connected with the polarization p...One hit of crystal meth causes birth defects
...fects in the fetal brain than in adult mice, which surprised me," says Wells. "In adults, you can see actual structural degeneration of the brain." U of T doctoral candidates Winnie Jeng and Andrea Wong and undergraduate Ryan Ting-A-Kee were also involved in this study. The research was supported by a grant f...Chickadees can help humans get their bearings
...chickadees, University of Alberta researchers were surprised to discover the birds contradicting prior research that showed how animals navigate. This study is the first to reveal a different pattern. Previously, only animals that had been raised in human-made enclosures had been tested. The findings are publ...Proteomics brings researchers closer to understanding microbes that produce acid mine drainage
... species in more ways than one. "We were somewhat surprised to see that Leptospirillum group III, that same minor organism, is also taking a lion's share of the responsibility in producing the extracellular polymers that make the biofilm matrix upon which all community members depend," Banfield said. "It's li...Research may provide new link between soft drinks and weight gain
...ontrol animals provided with water only. "We were surprised to see that mice actually ate less when exposed to fructose-sweetened beverages, and therefore didn't consume more overall calories," said Dr. Tschöp. "Nevertheless, they gained significantly more body fat within a few weeks." Results from an earlie...Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils
...he symbiotic relationship is formed, I wouldn't be surprised if the land-based relationships formed independently of the older marine relationships." "In fact, studies of modern lichens demonstrate that the lichen symbiosis evolved many times," Taylor said. "The ability to form a symbiotic relationship betwe...While on trail of dioxin, scientists pinpoint cancer target of green tea
...sts, by binding directly to it. We were completely surprised that this isn't the case," says Gasiewicz, whose work was funded by the National Institute of Environmental Health Sciences and the American Institute for Cancer Research. Instead, the team found that EGCG binds to HSP90, a protein that helps other ...An (ecological) origin of species for tropical reef fish
...genus Halichoeres) throughout their range and were surprised by what they found. Rocha explains: "I was interested in the Amazon barrier. The Amazon and Orinoco's freshwater and sediment discharge off of northeastern South America is so immense that it precludes coral reef formation from the mouth of the Amaz...Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes
...e experiments, published in 2004, researchers were surprised to find that they didn't have to give anti-rejection drugs to diabetic rats treated with embryonic pig cell transplants. They had expected rats that received no immune suppression would reject the transplants. Instead, the new tissues engrafted with ...Two chemicals boost immune cells' ability to fight HIV without gene therapy
...d the cells with the chemical compounds. They were surprised to see that the compounds produced the same three changes in the cells as those created by the gene therapy. "Lo and behold, we discovered we didn't need to use gene therapy to reactivate the telomerase and strengthen the immune system's capacity to...Stanford gut check shows diversity of intestinal ecosystem
...stine as well as among different people. "We were surprised at the degree to which an individual determines the particular picture of microbial diversity that we see," said Relman. "Variation between individuals had been suspected, but our data proved to be a dramatic confirmation of this belief." An interes...Disease progression model of pancreatic cancer developed by Penn researchers
...ssible targets for treatment. The researchers were surprised to discover a high degree of heterogeneity in expression among these key molecules across the specimens. After ruling out the likelihood that this variability resulted from additional acquired mutations in known key tumor suppressor pathways, Hingora...A puzzle piece found in unraveling the wiring of the brain
...ork appears today in the journal Neuron. "We were surprised to find an exocyst mutant having such specific defects," said Bellen, professor of molecular and human genetics at BCM. "The cell biological basis of brain wiring is largely unknown. We are happy to have a new handle on an old problem." Using sophis...New understanding of DNA repair may pave way to cancer treatments
...cle and cell death control. We were therefore most surprised to find an uncoupled function for the same protein," said Ronai. The finding of ATF2's novel function in DNA repair was serendipitous. As Shoichi Takahashi, a postgraduate researcher, was testing for the changes in ATF2 in human cancers, he "lost th...Silence the gene, save the cell: RNA interference as promising therapy for ALS
...neurological diseases such as ALS. "I would not be surprised to see, in the next ten years, this technology used for treating diseases of the nervous system, particularly diseases that involve toxic gain-of-function, such as inherited forms of Parkinson's disease or Huntington's disease," notes Aebischer. "But...Viral protein influences key cell-signaling pathway
...and Richard J. Solove Research Institute. "We were surprised to see p300 show-up among the many genes affected by this viral protein." HTLV-1 infects an estimated 15 to 20 million people worldwide. In about five percent of them, the infection will lead to adult T cell leukemia or lymphoma (ATLL). ATLL is an a...Vascular structure and function improve with diet and exercise
...to 90.9 kg (203.5 pounds to 200 pounds). "We were surprised that we saw such a weight reduction with the Mediterranean diet," Petrella said. "It was not a weight reduction program." Blood pressure did not change significantly. Ultrasound measurements of the heart and blood vessels at rest were performed as ...NC State scientist finds soft tissue in T. rex bones
...rely dissolve the entire fossil. But the team was surprised by what actually happened when they removed the minerals from the T. rex femur fragment. The removal process left behind stretchy bone matrix material that, when examined microscopically, seemed to show blood vessels, osteocytes, or bone building cel......ue as the acidity increased. The researchers were surprised to discover that, when the pH was raised from 4 to 10, the blue solution turned reddish once again--a strong indication that some cytochrome c molecules had refolded into their original three-dimensional shape. In fact, the experiment showed that, wh...