Scientists discover role for dueling RNAs
...ead these antisense transcripts are, I wouldn't be surprised if these findings eventually lead us to discover an entirely new level of gene regulation." Hongay is now searching the yeast genome for other genes that might be regulated by antisense RNA. ...High HPV concentrations combined with smoking significantly raise risks of cervical cancer
...ery high risk of later cervical cancer. "We were surprised to see this dramatically increased risk among women with high viral loads who smoked," Gunnell said. Among their findings: Women who smoked and had a high HPV-16 load during their first exam had a 27-fold increased risk of later cancer than wome......hought to feed only on invertebrates. The event surprised the scientists in two ways, he says. First, it showed that the species one would normally expect to "mow the weeds" may make little impression on a heavily-overgrown reef, dashing researchers' hopes that herbivores may be a way to restore heavily we...Wheat gene may boost foods' nutrient content
...e changes." Dubcovsky said the research team was surprised to find that all cultivated pasta and bread wheat varieties analyzed so far have a nonfunctional copy of GPC-B1, suggesting that this gene was lost during the domestication of wheat. Therefore, the reintroduction of the functional gene from the w...Buildup of damaged DNA in cells drives aging
...this key DNA repair enzyme. "We were completely surprised by the finding that the patient had a mutation in XPF, because mutations in this gene typically cause xeroderma pigmentosum, which is a disease characterized primarily by skin and other cancers rather than accelerated aging," said Dr. Hoeijmakers. "T...Researchers add to understanding of how brain cells communicate
...ate how NR1/2D receptors do this. Johnson was most surprised to find that the magnesium ion, which strongly blocks the channels of NR1/2A receptors, flows much more easily in NR1/2D receptors. In those receptors, magnesium acts more like a "permeant" ion, which means it can flow through the channel without get...USC team reveals structure of APOBEC family protein
...mic structure of the enzyme, the research team was surprised by the molecule's shape. "Based on what is known about proteins that catalyze a similar chemical reaction, we expected it to look more like a square. But instead, it resembles a butterfly," Chen said. "It's significant because this non-canonical, ...Immune cell communication key to hunting viruses, Jefferson immunologists show
...l receptors on killer T-cells. What they found surprised them. While the nanoparticle specifically bound to the surface of T-cells with receptors recognizing the viral-MHC complex, the control ?a biosensor that carried the same MHC protein with a different peptide not recognized by the T- cells ?unexpect...Electric fish in Africa could be example of evolution in action
...rent signals and different appearances, so we were surprised to find no detectable variation in the genetic markers we studied," Arnegard said. Because all of the 20 or so species of mormyrid have distinct electric signals, Arnegard believes the different impulses of the fish he studies might be their first s...Gene therapy prevents the onset of diabetic symptoms in mice
...slowly over five to 10 years, the researchers were surprised to find that by summer 2002, the soil acidity in both the top and lower layers of the test plot neutralized from being highly acidic to more acceptable levels for sugar maples. The researchers also found that by the second year, calcium levels in the...Acid rain causing decline in sugar maples, say researchers
...slowly over five to 10 years, the researchers were surprised to find that by summer 2002, the soil acidity in both the top and lower layers of the test plot neutralized from being highly acidic to more acceptable levels for sugar maples. The researchers also found that by the second year, calcium levels in the...Cutting calories slightly can reduce aging damage
... hearts, muscle and brains. The research team was surprised to find one of the biomarkers, RNA, which is important for coding DNA and for protein synthesis, is more quickly damaged by aging than the more frequently studied DNA. RNA damage, therefore, could be an excellent early signal to indicate the onset of...Corals switch skeleton material as seawater changes
...ction to analyze their mineral composition. He was surprised to find that corals grown in the artificial seawater with a magnesium-to-calcium ratio less than 2-to-1 began producing a large portion of their skeleton with the calcite mineral, while those grown in unmodified modern seawater produced exclusively t...Biologists find regions of rice domestication
... of where it came from." Schaal said that she was surprised and "delighted" by their results. "People have moved rice around so much and the crop crosses with its wild ancestors pretty readily, so I was fully prepared to see no domestication signal whatsoever," Schaal said. "I would have expected to see clu...UCLA study finds same genes act differently in males and females
...level in male and female tissue. What they found surprised them. While each gene functioned the same in both sexes, the scientists found a direct correlation between gender and the amount of gene expressed. "We saw striking and measurable differences in more than half of the genes' expression patterns betw...One therapeutic dose of radiation causes 30 percent spongy bone loss in mice
...traveling on long space flights. "We were really surprised at the extent of bone loss," said lead researcher Ted A. Bateman of Clemson University. "We're seeing bone loss at much lower doses of radiation than we expected." The mice suffered the loss of trabecular bone, the spongy area of bone inside the dens...Some people would give life or limb not to be fat
...e a limb or be blind than be overweight. "We were surprised by the sheer number of people who reported they would be willing to make major sacrifices to avoid being obese. It drives home the message that weight bias is powerful and pervasive," said Marlene Schwartz, associate director of the Rudd Center and ...Agriculture and tropical conservation: rethinking old ideas
...asant producers in tropical areas, they're usually surprised when they hear that conservationists think that they're the enemies of conservation," said Vandermeer, who is the Margaret Davis Collegiate Professor of Ecology and Evolutionary Biology. "They love their farms and all the plants and animals in the ar...'Sticky' mice lead to discovery of new cause of neurodegenerative disease
...t was disrupted by the sti mutation. They were surprised to find a subtle defect in a gene that codes for p...d tRNAs, may generate misfolded proteins. But what surprised us was that such a small increase in mischarged tRNAs could have such a devastating result in terms ...Heal thyself: Systems biology model reveals how cells avoid becoming cancerous
...cted, in repairing damaged DNA. However, they were surprised to find that a much larger part of the network is involved in modulating the expression of genes not directly related to DNA repair, such as genes involved in cell growth and division, protein degradation, responses to stress, and other metabolic fun...