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Tag: "suppress" at biology news

Learning during sleep?

...tential of individual interneurones (neurones that suppress the activity of the hippocampus) in anaethetised m...as a surprising finding, because the interneurones suppress those neurones in the hippocampus which are supposed to write information to the cerebral cortex pre...

'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance

...ep was to engineer a strain of bacteria that could suppress over-replication of the key plasmid. This so-called "Trojan horse" could then be used to spread the killer plasmid via conjugation to targeted bacterial pathogens that lacked the ability to resist over-replication. "We harnessed this plasmid," tho...

Peering into the shadow world of RNA

...to specific RNA editing, the result of which is to suppress ?or perhaps refocus ?miRNA expression and activity...esult, mechanisms have arisen through evolution to suppress their activity. This is particularly true in the egg and sperm, where maintenance of the genome’s in...

Fight weeds with plant pathogens

...anaging weeds. "The use of plant pathogens to suppress weeds is considered as one of the alternative weed control options for areas or production systems where the use of chemical herbicides is not permitted or feasible," said Erin Rosskopf, USDA, Agricultural Research Service, Fort Pierce, FL. "Plant pa...

Encouraging results in pancreatic cancer research

...tide, a naturally occurring human protein known to suppress tumor growth. The researchers previously found that PNC-28 induces death of a variety of human tumor cell lines, including a pancreatic cancer cell line, while not harming healthy cells. The research team has now given PNC-28 to laboratory animals ...

Microbes compete with animals for food by making it stink

...water with the antibiotic chloramphenicol added to suppress microbe growth. In the lab, stone crabs readily ate both freshly thawed menhaden and fish that had soaked in water with antibiotics, but refused to eat the rotten fish not protected from microbial attack. To determine if reducing bacterial growth ...

Widely used hepatitis B drug spurs HIV drug resistance

...fected patients who are not already using drugs to suppress HIV. "The good news is that co-infected patients already on HIV therapy can still use entecavir to treat their hepatitis B, but the bad news is that there are now fewer options for treating hepatitis B first," she adds. Hepatitis B infection atta...

Reactivated gene shrinks tumors

...ancers arise due to defects in genes that normally suppress tumor growth. Now, for the first time, MIT researchers have shown that re-activating one of those genes in mice can cause tumors to shrink or disappear. The study offers evidence that the tumor suppressor gene p53 is a promising target for human ca...

Improving outcomes in premature births

...& Gynecology. In previous studies of drugs to suppress labor contractions to allow the fetus more time to develop in utero, some drugs were able to delay delivery, but none improved the baby’s health outcome. This study is the first to show that the baby benefited from the therapy, especially those who a...

Plastic that degrades in seawater could be boon for cruise industry and others

...& Gynecology. In previous studies of drugs to suppress labor contractions to allow the fetus more time to develop in utero, some drugs were able to delay delivery, but none improved the baby’s health outcome. This study is the first to show that the baby benefited from the therapy, especially those who a...

Brain fends off distractions

...off distractions. If we are busy with something we suppress disrupting external influences. If we are tired, w... who were mentally fatigued were no longer able to suppress the distraction. Moreover they scored less well in their task. Suppression is therefore not automati...

Molecular tools make the cut

...off distractions. If we are busy with something we suppress disrupting external influences. If we are tired, w... who were mentally fatigued were no longer able to suppress the distraction. Moreover they scored less well in their task. Suppression is therefore not automati...

'Juiced-up' battery fueled by sugar could power small portable electronics

...off distractions. If we are busy with something we suppress disrupting external influences. If we are tired, w... who were mentally fatigued were no longer able to suppress the distraction. Moreover they scored less well in their task. Suppression is therefore not automati...

MicroRNAs can be tumor suppressors

...ee and Anindya Dutta have shown that microRNAs can suppress the overexpression of a gene called HMGA2. This gene is related to creation of fatty tissue and certain tumors, as well as diet-induced obesity. MicroRNA is a single-stranded RNA that is typically only 20-25 nucleotides long and is related to regu...

Scientists identify a gene that may suppress colorectal cancer

...rt the discovery of a gene that, when mutated, may suppress colorectal cancer. To conduct the study, the rese...y modifier genes, which may function to enhance or suppress tumor initiation, growth and/or progression. Atp5a1 is a modifier gene, and it is located on the ...

Scientists uncover new target in cancer mutation puzzle

...r suppressor gene. Mutant p53 loses its ability to suppress cancer cells. The UR team found that when cells...3 is functioning properly it appears to be able to suppress the Ras signals to Rho, and thus shut down the movement of cancer cells. This was a previously unkno...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

...gnaling pathways well enough, you can stimulate or suppress the immune response in the right way at the right time to create safe and effective therapies.? According to Bowick, the Pichinde experiments have already generated some therapeutic leads, thanks to the unexpected discovery that a growth factor rec...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...ld be in controlling the regulatory T cells, which suppress the immune system, says Lepisto. Prior to vaccination, the pancreatic cancer patients had significantly more regulatory T cells than normal, which then increased following each injection. Likewise, the patients also experienced an increase in effecto...

Antibody therapy prevents type 1 diabetes in mice

... have demonstrated that CD137 antibody therapy can suppress the development of type 1 diabetes in mice and that the effect is dependent on the induction of a certain subset of regulatory T-cells. If we can demonstrate this same genetic predisposition and therapeutic effect in human type 1 diabetes patients, t...

A genetic 'gang of 4' drives spread of breast cancer

...terference, in which RNA molecules are tailored to suppress expression of target genes. "We found that depriving aggressive metastatic tumor cells of these genes decreased both their ability to grow large aggressive tumors in the mouse mammary gland and also the ability to release cells from these tumors in...

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