MSKCC researchers uncover structure of key protein complex in cells
...vidence that SUMO is important in cancer, research suggests that it is necessary for the normal assortment of chromosomes immediately before a cell splits. Yeast cells that lack SUMO cannot successfully divide, Dr. Lima noted. Since cancer is characterized by cells dividing unchecked, proving SUMO's function...Agricultural antibiotic use contributes to 'super-bugs' in humans
... the use of antibiotics in agriculture. "Evidence suggests that antibiotic use in agriculture has contributed to antibiotic resistance in the pathogenic bacteria of humans," say David Smith of the Fogarty International Center, Jonathan Dushoff of Princeton University and the Fogarty International Center, and...Brain networks change according to cognitive task
... (LTC for rhyming, IPS for spelling). This finding suggests that task specific regions serve as convergence zo...the IFG on the task specific regions. This finding suggests the IFG plays a pivotal role in "making" task specific regions more or less sensitive, depending on ...Researchers develop new testing methods for potential monkeypox or smallpox outbreak
... closely related to smallpox. This new information suggests that the 2003 outbreak was larger than the 72 cases reported by the Centers for Disease Control and Prevention (CDC). The research was released online this week by the medical journal Nature Medicine. The study will also appear in the September 2005 ...North & South American researchers find architectural abnormalities in T. cruzi ribosome
...ceedings of the National Academy of Sciences, also suggests that the parasite has a unique scanning mechanism for translating genetic information into proteins. "This may lead the way to the discovery or development of drugs that are specific against an essential mechanism of the life of the parasite and do ...DDT-resistant insects have additional genetic advantage that helps resistance spread
... the University of Bath, who led the study. "This suggests that by becoming DDT resistant the female flies are passing on some unknown advantage to their progeny, presumably associated with the single metabolic enzyme (cytochrome P450) that they over express.'' "These results are important for the use of an...Immune system has evolved to prevent autoimmune disease
Study suggests chronic infections may create autoimmune response ... of the correlation is controversial. Rice's model suggests that a correlation does exist, but that the length of the infection prior to onset of autoimmune dis...Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases
...e able to find another route out of the cell. This suggests that Rab9 and other components of this exit pathway might be attractive targets for antiviral therapies for a variety of viruses. Blocking Rab9 may have significant side effects, but there are people who live without Rab9, Hodge explained. Although ...Discarded placentas deliver researchers promising cells similar to embryonic stem cells
... controversial counterparts, embryonic stem cells, suggests a University of Pittsburgh study to be published in the journal Stem Cells and available now as an early online publication in Stem Cells Express. A part of the placenta called the amnion, or the outer membrane of the amniotic sac, is comprised of c...New technology shows our ancestors ate…everything!
...data for the two species. The researchers say this suggests that both species relied on their less preferred foods during periods of food scarcity. "If members of a species live in a seasonal environment, they can get all the soft fruit they need during the wet season," Teaford added. "But come dry season, th...UNC scientists discover new role for protein as fundamental inhibitor of cell movement
...st of other proteins in the cell. Thus, the study suggests that CIB1 may be a likely target for new drug development aimed at decreasing tumor metastasis, or spread, throughout the body. "I was ecstatic to see these results and to discover that it also regulates the fundamental process of cell migration," s...Out of sight, out of mind? Not necessarily
... Academy of Sciences' (PNAS) online Early Edition, suggests the brain has more than one pathway along which visual information can be sent. For the study, the researchers induced temporary, reversible blindness lasting only a fraction of a second in nine volunteers with normal vision. Transcranial magnetic s...Vaginal gel may provide a new approach to HIV prevention
...he animals against an HIV-like virus. The research suggests that a microbicide using compounds that inhibit the processes by which HIV attaches to and enters target cells could potentially provide a safe, effective and practical way to prevent HIV transmission in women, according to study investigators. The s...Does manganese inhaled from the shower represent a public health threat?
...just yet! A new analysis based on animal studies suggests that showering in manganese-contaminated water for a decade or more could have permanent effects on the nervous system. The damage may occur even at levels of manganese considered safe by the Environmental Protection Agency, according to researchers ...U-M scientists discover identifying markers for primitive blood-forming stem cells
...e bloodstream so quickly," Morrison adds. "It also suggests that endothelial cells produce substances that regulate and nurture the growth of these stem cells. If we can identify these growth factors, it could help us learn how to manipulate and grow colonies of HSCs outside the body, which could lead to new ...MBL researchers probe how an ancient microbe thrives and evolves without sex
...khipova and Matthew Meselson provide evidence that suggests bdelloid rotifers--which probably gave up sex at least 50 million years ago but have still evolved into 370 species--handle DNA transposons more efficiently than other asexual species. Transposons are small snippets of "junk DNA" that sexual reproduc...Picky female frogs drive evolution of new species in less than 8,000 years
...er of the original frog populations. This example suggests that rapid speciation is often driven by recontact between long-isolated populations, Moritz said. Random drift between isolated populations can produce small variations over millions of years, whereas recontact can amplify the difference over severa...New research puts a fresh spin on current thinking of speech evolution in humans
...eech production. This discovery is important as it suggests that this area of the brain evolved originally to perform high-order control over the mouth and the jaw, and that as humans evolved this area came to control the movements necessary for speech. "Our study shows that nonlinguistic monkeys possess an ...Hepatitis C complicated by morphine withdrawal
...ght off viral infection, including HIV, this study suggests that morphine withdrawal weakens host cell immunit...i-HCV factor (IFN-alpha) production by liver cells suggests that �opioid abuse may contribute to the chronicity of HCV infection and promote HCV disease progres...... stimuli," concluded the researchers. "This result suggests that an organism may seek to distribute its sensory resources according to the behavioral relevance of the natural important stimuli, rather than according to purely statistical principles. "For instance, if a few important stimuli within the natura...