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Tag: "successfully" at biology news

Johns Hopkins lab scientists tame overactive CF protein

...ns Children's Center scientists has identified and successfully tamed an overactive protein that plays a key role ...terference on cells in the laboratory, researchers successfully intercepted signals sent out by the rampant protein and prevented cell damage by the protein, effect...

UF scientists test improved gene therapy method for hereditary heart conditions

...hers report. UF researchers used the approach to successfully reverse symptoms in mice with a form of muscular dystrophy that damages the heart. They also tested the virus-based delivery method in monkeys and found genes were readily absorbed by heart muscle cells, and the effect persisted for months. The fin...

A catalogue of proteins

...s Mann and his colleagues, and has previously been successfully used to determine the composition of single cell-organelle protein. After the individual "compartments" for the proteins were identified, the scientists compared corresponding protein sets of individual cell organelles. Among the 1400 different prot...

Silence of the amoebae

...llness. Now the scientists have developed a way to successfully silence the expression of two additional virulence genes in the same amoebae. Rivka Bracha and colleagues in the lab of Prof. David Mirelman in the Biological Chemistry Department had shown that expression of the gene coding for the toxic protein c...

Creating a window on 'oceans in motion'

...extensively along shelves. A pilot array has been successfully demonstrated by the British Columbia-based Project POST (Pacific Ocean Shelf Tracking), part of the international Census of Marine Life. The current array stretches more than 1,750 km, from Oregon through British Columbia to north of the Alaskan pa...

A more powerful and efficient engine for rice: the C3-C4 challenge

...wth. Dr. Sheehy compared the potential impact of successfully transforming rice from a C3 to a C4 plant as even ...ants that sparked the Green Revolution. "If we can successfully develop a C4 rice plant, the implications and potential impact will be huge--it's one of the great s...

With few factors, adult cells take on character of embryonic stem cells

...ntroduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell, published by Cell Press. The cells--which the re...

Computational model simulates AZT metabolism in mitochondria

...g zidovudine (azidothymidine, AZT). AZT is used successfully as part of Highly Active Anti-Retroviral Therapy (HAART) to control the level of the human immunodeficiency virus in HIV-infected individuals. However, long-term use of AZT may lead to side-effects in some patients. David Samuels and coworkers are in...

Montreal researchers identify defects of immune cells

...ut de recherches cliniques de Montréal (IRCM) have successfully identified a defective immune cell population that determines susceptibility to candidiasis, a common and often debilitating infection in individuals infected with the human immunodeficiency virus (HIV). These findings, revealed using a model of cand...

Virtual realities against pain

...e technique of distraction has been researched and successfully applied in clinical practice in order to reduce pain associated with certain medical procedures. The use of distraction is based on the assumption that there is an important psychological element in the perception of pain, with the amount of attentio...

Stanford doctors advance in bid to turn mice stem cells into blood vessels

...cal resident Oscar Abilez, MD, and colleagues have successfully differentiated the stem cells into myocytes, one of the building blocks of blood vessels, after placing them in a life-like growth environment that the research team had created. The scientists hope to be able to eventually grow whole blood vessels t...

UC Davis researchers move biotechnology closer to replacing electronic pacemakers

UC Davis researchers have successfully used a custom designed protein and gene delivery system to restore normal heart rhythms in pigs with electronic pacemakers, reducing their dependence on implanted devices. This work suggests that scientists are one step closer to making bioengineerin...

UF scientists restore sight to chickens with blinding disease

... "I will always remember the first animal that we successfully treated," said Semple-Rowland, who is also a member of the UF Center for Vision Research and the UF Genetics Institute. "I thought I saw signs that the chick was responding visually to the environment, but I didn't want to believe it. Scientists alwa...

BGSU biologist trying to crack microscopic code

...nicillin, one of several existing antibiotics that successfully target specific structures required for the barrier function to work, Larsen notes. The outer membrane is stabilized by a grid of sugar polymers, and penicillin wrecks the grid, making the cells susceptible to a body's natural defenses. Disrupting ...

On the track of tiny larvae, a new model elucidates connections in marine ecology

...phic and genetic models allowed the researchers to successfully predict genetic patterns on a regional scale. This breakthrough approach to integrating genetic and oceanographic models helps predict genetic links among several locations and is an important new tool for the management and ecological study of marin...

Spinal cord bridge bypasses injury to restore mobility

...s of the leg. While peripheral nerves can be used successfully as grafts in the limbs, spinal cord injuries put up defenses called inhibitory chondroitin sulfate proteoglycans that create molecular guardrails within scars at the lesion site. These scars act as a barrier to regenerating axons and result in loss...

Slow-frozen people? Latest research supports possibility of cyropreservation

...ing sperm and embryos, currently can be frozen and successfully rewarmed. A major problem hindering wider use of cyropreservation is formation of ice crystals, which damage cell structures. Cyropreservation may be most familiar, however, as the controversial idea that humans, stricken with incurable diseases, mi...

Novel therapy combinations gain ground in treating hepatitis

...chers are finding that the diseases may react more successfully to a longer duration of therapy. In this study, researchers at the University of Tuebingen in Germany compared two combination therapies for an extended treatment period of 72 weeks, compared to the current standard of 48 weeks, in patients with chr...

Researchers seek to solve mystery of natural HIV control

... which may not cure or prevent infection but could successfully suppress viral levels. Since this natural ability is so rare, we need to work with collaborators around the world to recruit the number of participants we will need to determine what is going on. "We expect to need data from at least 1,000 such i...

New GI technologies improve internal organ visualization

...le. In each case, however, EUS-guided angiography successfully and clearly highlighted the vessels. "We feel th... level of sedation. All procedures were completed successfully and six patients had at least one polyp removed. Of the 24 patients, 14 (7 colonoscopy and 7 endosc...

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