New egg freezing technique offers hope to hundreds of women
... injection), and 50% of the resulting zygotes were successfully developed for embryo transfer. Twelve pregnancies ...ventional slow freeze-thawing method has been used successfully for human embryos in assisted reproduction for two decades, but has been far less successful for ooc...Life and death in the hippocampus: what young neurons need to survive
...cular survival gear required for a young neuron to successfully jump into the fray and hook up with other cells. In a study published in a forthcoming issue of Nature, researchers in the lab of Fred H. Gage, Ph.D., a professor in the Gene Expression Laboratory and the Vi and John Adler Chair for Research on Ag...With few factors, adult cells take on character of embryonic stem cells
...ntroduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell. The cells--which the researchers designate "indu...Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity
...hemistry, researchers at The Wistar Institute have successfully determined the three-dimensional structure of the p53 protein bound as a dimer to DNA and used the structure to produce an accurate model of the p53 tetramer bound to DNA. "The bottom line is that we now have a detailed picture of how p53 binds DNA...New light microscope sharpens scientists' focus
...l protein they are studying has been developed and successfully demonstrated by scientists at the Howard Hughes Medical Institute's Janelia Farm Research Campus in collaboration with researchers at the National Institutes of Health and Florida State University. The new technique far surpasses the resolution of ...Quitting smoking improves lung function considerably
...group and those who quit. Of the 10 subjects who successfully stopped smoking and completed the six-week study, five used nicotine patches, one employed acupuncture and four quit without any aid. The researchers believe that their findings highlight the importance of smoking cessation for adults with asthma. ...Ten years later, Dolly is still making headlines
...searcher of a team of scientists who were first to successfully clone an animal, Dolly the sheep, ten years ago, will speak about his plans to clone embryos to alter disease genes in humans. Wilmut will be joined by two other leaders in biotechnology research, Dr. Kevin Eggan of the Harvard Stem Cell Institute, w...Study shows pine bark naturally decreases severe chronic venous insufficiency
...m getting larger and more prominent. When edema is successfully treated, the increased pressure on veins gets normalized, preventing the veins from further increasing in size. "Pycnogenol® has demonstrated its efficacy and safety in several clinical trials and symptoms of CVI have been reduced significantly by ...Gene therapy injected into the brains' of mice with Huntington's disease
...enter, Chicago, and Ceregene Inc., San Diego, have successfully used gene therapy to preserve motor function and stop the anatomic, cellular changes that occur in the brains of mice with Huntington's disease (HD). This is the first study to demonstrate that, using this delivery method, symptom onset might be prev...Sperm created in the laboratory from embryonic stem cells produce viable progeny
...ization and the resulting early stage embryos were successfully transplanted into mice. Six of the seven mice born...ional sperm in the laboratory which can be used to successfully fertilize eggs and support full-term development into embryos and adult mice. "Our approach provides...A sweet solution for Alzheimer's disease?
...o destroy amyloid â, for example, was first tested successfully in the same type of mice used in the scyllo-inositol studies, but the vaccine turned out to be toxic in some humans. It caused an autoimmune reaction in about 10 percent of patients who were immunized, St George-Hyslop said. Autoimmune responses sh...Compound in dairy products targets diabetes
Fatty acids commonly found in dairy products have successfully treated diabetes in mice, according to a researcher at Penn State. The compounds, known as conjugated linoleic acids (CLA), have also shown promising results in human trials, signaling a new way of potentially treating the disease without synthetic d...Leptin found to control appetite and limb development in frogs
...mans, so Denver's lab had some puzzles to solve to successfully clone the frog gene. But once they solved those issues and put the gene into E. coli bacteria to make quantities of leptin, the frog protein turned out to be functionally very similar to the human version, Denver notes. "It would appear that leptin...The higher the hierarchy, the greater the aggression
...the likelihood that an individual will get to mate successfully in that society based on their rank--or place in the social hierarchy. They can only pass on their genes when they reach the top of the hierarchy, usually after those ahead of them in the rank have died and they have inherited the right to reproduce....MUHC announces a transplant first in Quebec
...strong interest in transplantation, allowing us to successfully offer combined organ transplants within one institution." The world's first heart transplant was conducted less than forty years ago; complex combined transplants have only been conducted since the 1980's. Multi-organ transplants, such as the combin...Origen publishes in Nature a robust and versatile method for creating transgenic chickens
...at Origen. "These cells ?which we are the first to successfully culture without changing their commitment -- proved to be the key to introducing genetic elements into the chicken genome. As a result, we can now take transgene designs that work well in model systems and breed flocks of birds depositing therapeutic...'Smart' genetic therapy helps the body to heal itself
...or Wirth's team identified a drug ?valproate, used successfully in epilepsy treatment for decades ?that is able to increase SMN protein levels 2-4 fold in cell lines derived from SMA patients. Later, they showed that valproate also raised SMN levels in neuronal tissues such as cultured brain slices derived from...Unique soybean lines hold promise for producing allergy-free soybeans
... discovered P34 in the early 1990s and in 2003 had successfully used a gene-silencing technique to create a soybea...ewly identified lines occur naturally, they can be successfully crossed into other soybean lines "without any biotechnology-derived component," the researchers note...Tests may help answer questions about GMOs and allergies
...ether the model works on a variety of proteins. If successfully validated, the testing could be available commercially in about five years. Perhaps the best known case of a genetically engineered crop potentially causing allergies was StarLink corn. Created by Aventis in 1996, StarLink contained the cry9C protei...A commercially developed vaccine has successfully protected mice and ferrets against a highly lethal avian influenza virus, according to the investigator who led the study at St. Jude Children's Research Hospital. The vaccine was developed by Vical Incorporated in San Diego, California. This findin...