New binding target for oncogenic viral protein
...tant cancer-preventing proteins, p53 and pRb. In a study published in the Journal of Biological Chemistry, ...its loss in tumors," Dr. Welcker emphasized. "The study of DNA tumors viruses has been an extremely important tool in understanding the cellular pathways th...Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
...y are good predictors of human biology, the Joslin study has important implications. "People and their doct...whammy." Other researchers involved in the Joslin study included co-authors Jose C. Jimenez-Chillaron, Ph.D., Marcelino Hernandez-Valencia, M.D.; also Carol...Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
...nteers will notknow whether they are receiving the study drug or the placebo.The goal of the study is to determine if and how much GM-CSF willincrease the number of circulating EPCs in patients with ...Fox Chase Cancer Center scientists identify immune-system mutation
...directs them to the killer-cell pathway. "Our new study identifies this defect as a point mutation in the ... In addition to providing a unique animal model to study the SCID syndrome, SCID mice have become a highly valuable tool for studying the immune system and a...Neuronal 'traffic jam' marks early Alzheimer's disease
...ople, to then test for transport defects, and then study whether those defects produce pathology similar to that seen in Alzheimer's. One of the questions they will also ask is whether amyloid plaques poison the transport machinery. If the experiments do, indeed, confirm the predictions of the transport hy...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
...and the Salk Institute in La Jolla,California.In a study published online January 23, 2005 in the journal N... stem cells,including those currently approved for study under federal funding inthe U.S., contain a non-human, cell-surface sialic acid calledN-glycolylneur......funding sources of research cited in the ads. The study is published in the Feb. 15 issue of the Canadian ...from the drug companies," said Dr. David Schriger, study author and professor of Emergency Medicine at UCLA. In comparison, out of the 400 journal articles,...Drug That 'Tags' Decision-making Areas Of The Brain May Aid
Along with aiding efforts to study addictedsmokers, a new drug that attaches only to ... nicotine receptors also gives us the potential to study whysome people are more addicted to nicotine than others,?Mukherjee said.Additional information : Ch...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
...lzheimer's-like condition.The mice he used for the study had two mutations. One, utilized byscientists at Eli Lilly, causes amyloid plaques to build up, creatingthe Alzheimer's-like condition. The second, developed by scientists atWashington University, causes some of the mouse brain cells to producea dye ...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...24 issue of Nature, presents the first genome-wide study of an amoeba. It is also the first genome sequence...complex organisms. Detailing the first systematic study of relatively recent horizontal gene transfer into a protist, scientists report evidence in the DNA ...Key molecule in plant photo-protection identified
...lzheimer's-like condition.The mice he used for the study had two mutations. One, utilized byscientists at Eli Lilly, causes amyloid plaques to build up, creatingthe Alzheimer's-like condition. The second, developed by scientists atWashington University, causes some of the mouse brain cells to producea dye ...Antarctic ice shelf retreats happened before
..., Edinburgh and British Antarctic Survey (BAS). A study of George VI Ice Shelf on the Antarctic Peninsula ...sintegration of ice shelves like Larsen B, the new study suggests that the ocean may play a more significant role in destroying them than previously thought....Anti-bacterial additive widespread in U.S. waterways
...carban contamination is greatly underreported. The study ispublished in the current online edition of Envir...riclocarbanconcentrations for 85 U.S. streams. The study results suggest that theantimicrobial contaminant is present in 60 percent of the U.S. waterresource...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these g...Plants, animals share molecular growth mechanisms
...e of types of cells in the plant." Results of the study are published in the February issue of the journal...plants and animals. The other researchers on this study were Dipanwita Basu and Salah El-Din El-Essal, research assistants; postdoctoral students Jie Le, Ch...Researchers Uncover Key Step In Manufacture of Memory Protein
...m she and her colleagues deciphered in the current study may provide insight into long-term memory deficits. She explained that other researchers have learned that some human beings lack normal CPE due to mutations in the CPE gene. Future research may determine if the CPE mutation affects these individuals...Plants respond similarly to signals from friends, enemies
...niques that allow for real-time, three-dimensional study in living cells over time, the NC State researcher...he very same bacterial machinery against it." The study started as a graduate research project of Ravisha R. Weerasinghe, the lead author of the paper, in t...Scientists Replicate Hepatitis C Virus in Laboratory
...V in cell culture will allow researchers to better study the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes and Digestive and Kidney ...Research advances quest for HIV-1 vaccine
...arch Institute in La Jolla, California performed a study examining the detailed molecular structure of the ...e 3D structure adopted by these amino acids. These study results suggest that 4E10 interacts with gp41 at a conserved region very close to the surface of the......ciated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lung cells and can ...