Interactive 3-D atlas of mouse brain now available on web
...gmented structures, including variability of brain structures across the strain, and downloadable visualization tools. The research that makes up this database was published as a cover article in the October 2005 issue of the journal Neuroscience. ...Bones from blood: Scientists aim to break new ground on fractures
...y are heading the EC-backed project to create bone structures from cord blood stem cells for use in the repair o...lls and investigate how we can turn them into bone structures for use as 3D bone replacements." Dr Genever said if the creation of bone structures from stem cell...Pair of studies offer new clues to combat antibiotic resistance
...r protective layer of lipopolysaccharides, complex structures that help them defend against antibiotic attack. R...d by key enzymes to make teichoic acids, polymeric structures in the membrane surrounding gram-positive bacteria. The polymers are considered essential for bacter...New evidence questions the simple link between prion proteins and madcow disease
... in to the lymph. It was not, however, taken up by structures called Peyer's nodules, that are believed to be the places where animals amplify the infective agent. "The fact the PrP isn't taken up by the Peyer's nodules questions whether PrP is really infectious, or whether PrP is really just a secondary marke...Scientist uses dragonflies to better understand flight
... at what happens naturally. Look at how such thin structures as falling paper move through a fluid environment like air, she said, and then examine how insects use their wings to manipulate that environment and stay aloft. "The major question I focus on is the question of efficiency," Wang said in an intervie...'Banana-jawed' fossil mammal linked to rare sound-producing skill
...ne? Previous research, he said, suggested such jaw structures likely were found in females. The researchers then analyzed incisor teeth, located in the front of the jaw and used for biting. In modern hyraxes, males have larger incisors than females. Among the fossils analyzed, measurements showed that those wi...'Accelerated evolution' converts RNA enzyme to DNA enzyme in vitro
... all of which have the ability to form base-paired structures with themselves and with RNA. Cross-pairing would allow genetic information to be transferred from these pre-RNA molecules to RNA. The catalytic function of these early enzymes might have been transferred to a corresponding RNA enzyme following the a...Gene needed for butterfly transformation also key for insects like grasshoppers
...he organism eventually becomes an adult, but adult structures such as the wings are severely undersized. "Broad is not required to transform into the adult, but it is needed to move through the series of nymphal stages," she said. "An insect should look different from one stage to the next, but if you remove b...GlycoFi announces the first production of antibodies with human glycosylation in yeast
...oduction of monoclonal antibodies with human sugar structures in yeast. This research, published online Januar...ogy, demonstrates that antibodies with human sugar structures (glycosylation) can be produced in glyco-engineered yeast cell lines, and that by controlling the su...'Executive' monkeys influenced by other executives, not subordinates
...athways by which social information feeds into the structures that control the eyes. And, we can explore whether such influences as hormonal levels, particularly testosterone, influence ranking. For example, we can manipulate testosterone levels, or give anxiety-reducing drugs, to determine an effect on social ...Gene therapy 'turns off' mutation linked to Parkinson's disease
...arkinson's disease. Alpha-synuclein is abundant in structures known as Lewy bodies ?a diagnostic hallmark of Parkinson's disease. Research has shown that mutant forms of the alpha-synuclein gene, as well as too much alpha- synuclein protein, are involved in the development Parkinson's disease in some families....Aggression-related gene weakens brain's impulse control circuits
...and their connections) of about 8 percent in brain structures of a mood-regulating circuit (cingulate cortex, amygdala) among other areas. Volume of an area important for motivation and impulse regulation (orbital frontal cortex) was increased by 14 percent in men only. Although the reasons are unknown, this co...Researchers solve mystery of how nuclear pores duplicate before cell division
...Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into ...f the journal Science. Nuclear pores are gigantic structures that control the transport of molecules such as RNA and protein in and out of a cell's inner sanctum...Study in Science holds promise for a new approach to drug therapy
... molecules from an existing database of 1990 known structures would bind tightly to the hotspot, and to rank them. In general,tight binding suggests that a drug candidate has the potential to remain bound to its target long enough to have the desired effect. Of the compounds found through the screen, one, calle...A new focus for the mechanism of nerve growth
...ivision. "Past research has focused on how actin structures are assembled at the leading edges of motile cells...mill." Recycling of actin bundles at the ends of structures called filopodia was most strongly affected. This is important because filopodia are thought to play...Forsyth scientists gain greater understanding of how embryos differentiate left from right
...iously held hypothesis that cilia (short hair-like structures on a cell) were the primary agents allowing an embryo to correctly position its internal organs along the left-right axis. Instead, their research showed a single asymmetry mechanism linking ciliary, serotonergic (serotonin is the chemical substance ...Single microRNA causes cancer in transgenic mouse
...the point where a B cell normally begins to create structures necessary for antibody development. "We believe that miR 155 initiated the process that blocked further differentiation of these cells," says Costinean. Croce says the results are consistent with previous study findings. "We know that miRNAs ofte...Alzheimer's study first to explain death of brain cells
...ppens, the cell's mitochondria, which are the tiny structures inside brain cells that produce the energy the cells need to function, begin to decay. Dr. Atamna refers to this phenomenon as a "functional heme deficiency" because the cells are still forming heme, but it is trapped within an amyloid-beta/heme comp...Key heart and Alzheimer's disease protein imaged for first time in native state
... now, we've only been able to model the lipid-free structures of these proteins, and now we can begin learning about their lipid-bound forms," says lead author Clare Peters-Libeu, a GICD and GIND research scientist. "It's a huge step forward for those of us involved in the field." ApoE, and particularly apoE4,......ppens, the cell's mitochondria, which are the tiny structures inside brain cells that produce the energy the cells need to function, begin to decay. Dr. Atamna refers to this phenomenon as a "functional heme deficiency" because the cells are still forming heme, but it is trapped within an amyloid-beta/heme comp...