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Tag: "structural" at biology news

MSKCC researchers uncover structure of key protein complex in cells

...ignaling reactions," said Christopher Lima, PhD, a structural biologist at the Sloan-Kettering Institute and lea...dings could help researchers understand both. "The structural network has revealed a mechanism that may be important in the regulation process in the SUMO and ubi...

New discovery blurs distinction between human cells and those of bacteria

UCLA biochemists reveal the first structural details of a family of mysterious objects called microcompartments that seem to be present in a variety of bacteria. The discovery was published Aug. 5 in the journal Science. "This is the first look at how microcompartments are built, and what the ...

Cells direct membrane traffic by channel width

...August issue of Structure, they show that the main structural difference that makes an aquaporin a glycerol channel is a channel that is just a hundred-millionth of a centimeter -- an angstrom -- wider than a normal water channel. So even if glycerol molecules line up properly, as do water molecules to pass th...

Learning how SARS spikes its quarry

...otein complex, the crystals were then subjected to structural analysis using x-ray crystallography. In this widely used technique, x-rays are directed through crystals of a protein. The resulting diffraction pattern is analyzed to deduce the atomic structure of the protein or protein complex under study. The ...

UCSD discovery may provide novel method to generate medically useful proteins

...different amino acid, and a protein with different structural and chemical properties is created. Antibodies are another type predator protein that must respond to rapidly evolving prey proteins, because microorganisms are constantly altering proteins on their surfaces to evade the immune system. Unlike the p...

Researchers find how some antibiotics kill bacteria

...he continued. All rifamycins belong to one of two structural classes. The researchers used two clinically impor...ins ?rifapentin and rifabutin ?that represent each structural class. They obtained samples of the antibiotics in their respective crystal structure form. Crystal ...

Genomics researchers discover protein deficit that causes drug toxicity

...yo Clinic researchers have discovered an inherited structural mechanism that can make drugs for some diseases toxic for some patients. The mechanism decreases a protein and in turn causes certain individuals to metabolize thiopurine drugs differently. Thiopurine therapies are used to treat patients with childho...

Methamphetamine Abuse, HIV Infection Cause Changes in Brain Structure

...ifornia-San Diego conducted brain scans to analyze structural volume changes in 103 adults divided among four populations: methamphetamine abusers who were HIV-positive; methamphetamine abusers who were HIV-negative; nonabusers who were HIV-positive; and nonabusers who were HIV-negative. They also assessed the ...

Living with salt

... of the Structural Biology Department revealed the structural basis of a remarkably salt-tolerant Dunaliella enz...ative/positive/ neutral mix. This and other unique structural features may enable the algal carbonic anhydrase to be active in the presence of salt, though not de...

Possible treatment found for 'chemobrain'

...t effective strategies for revealing the important structural and functional elements of the human genome sequen...uence data will also provide new insights into key structural and functional elements of the Anopheles genome. The roundworm genome is important because its sequ...

NHGRI Selects 13 More Organisms for Genome Sequencing

...t effective strategies for revealing the important structural and functional elements of the human genome sequen...uence data will also provide new insights into key structural and functional elements of the Anopheles genome. The roundworm genome is important because its sequ...

Genome Sequence for Haemophilus Influenzae Completed

...l genetics and isotope dynamics, John is the first structural molecular biologist that we have worked with," says wildlife biologist Rolf Peterson from Michigan Technological University (Houghton, Mich.), who has spent the last three decades doing field research on Isle Royale. "It was a delight to learn about ...

Otter adaptations: How do otters remain sleek and warm

...l genetics and isotope dynamics, John is the first structural molecular biologist that we have worked with," says wildlife biologist Rolf Peterson from Michigan Technological University (Houghton, Mich.), who has spent the last three decades doing field research on Isle Royale. "It was a delight to learn about ...

Study: Predatory dinosaurs had bird-like pulmonary system

...ating dinosaurs such as T. rex in fact shares many structural similarities with that of modern birds, which, from an engineering point of view, may possess the most efficient respiratory system of any living vertebrate inhabiting the land or sky," said Claessens, who received a Ph.D. from Harvard in organismic ...

Rensselaer researchers develop approach that predicts protein separation behavior

...about the complex relationship between a protein's structural features and its chemical binding properties, and also aid in evaluating its potential biomedical applications." The research findings are reported in the Aug. 16 issue of Proceedings of the National Academy of Sciences in a paper titled "A Priori...

3D Atlas Will Help Navigate The Spinal Cord

... the problem is greater: there is no comprehensive structural study of the spinal cord of any species, including...ming. The results will provide (a) the fundamental structural map of the rat spinal cord, (b) make relevant comparisons with the human spinal cord and demonstrate...

Researchers at UGA provide first look at protein expression in Chagas disease-causing parasites

...y costs in the naval industry. Shark skin offers a structural design that prevents this so called 'bio-fouling'. Ralph Liedert from the University of Applied Sciences, Bremen, Germany, is presenting his work on the application of artificial shark skin in a new anti-fouling strategy at the Society for Experimen...

Three deadly parasite genomes sequenced

...y costs in the naval industry. Shark skin offers a structural design that prevents this so called 'bio-fouling'. Ralph Liedert from the University of Applied Sciences, Bremen, Germany, is presenting his work on the application of artificial shark skin in a new anti-fouling strategy at the Society for Experimen...

Ethical guidelines suggested for research that would put human stem cells in primates

...y costs in the naval industry. Shark skin offers a structural design that prevents this so called 'bio-fouling'. Ralph Liedert from the University of Applied Sciences, Bremen, Germany, is presenting his work on the application of artificial shark skin in a new anti-fouling strategy at the Society for Experimen...

Experts discuss use of human stem cells in ape and monkey brains

...y costs in the naval industry. Shark skin offers a structural design that prevents this so called 'bio-fouling'. Ralph Liedert from the University of Applied Sciences, Bremen, Germany, is presenting his work on the application of artificial shark skin in a new anti-fouling strategy at the Society for Experimen...

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