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Tag: "strong" at biology news

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

... immune system) and nanoparticles that exhibited a strong preferential binding to targeted cancer cells. In what marked the first-ever synthesis of a nanoparticle-aptamer bioconjugate, the nanoparticles were conjugated to RNA aptamers that bind to the prostate specific membrane antigen (PSMA) ?a well know...

Researchers use 'trickery' to create immune response against melanoma

... immune system) and nanoparticles that exhibited a strong preferential binding to targeted cancer cells. In what marked the first-ever synthesis of a nanoparticle-aptamer bioconjugate, the nanoparticles were conjugated to RNA aptamers that bind to the prostate specific membrane antigen (PSMA) ?a well know...

UCLA imaging study of children with autism finds broken mirror neuron system

...gether with other recent data, our results provide strong support for a mirror neuron theory of autism. This is exciting because we finally have an account that can explain all core symptoms of this disorder." Conducted at the Semel Institute's Ahmanson-Lovelace Brain Mapping Center, the research used func...

Birth defects: 8 million annually worldwide

...ections. Data in the March of Dimes report make a strong argument for recognizing and addressing the significant contribution of birth defects to infant and childhood mortality if the U.N. goal is to be achieved. ...

Duke to test bird flu vaccine dosing

... to determine whether the vaccine still triggers a strong immune response at lower doses. The seven-month ...gh doses and at least two injections to initiate a strong response, Walter said. Trial participants will receive varying strengths of the H5N1 vaccine, eithe...

Hormonal male contraception reversible after few months for all men

... Dr Liu and colleagues comment: "Our data provide strong assurance that the previously described efficacy of hormonal male contraceptives is coupled with highly predictable recovery to semen characteristics that are compatible with fertility. These findings thereby increase the promise of new contraceptive...

Infection 'alarm' yields clues to immune system behavior

..., involving only nearby cells. If TNF's signal was strong enough to set off an immune response involving the entire body, the result could be a high fever and septic shock. "We've developed a better understanding of why the fight against a local infection stays local," said Raymond Cheong, a graduate studen...

Researchers map of genetic variations implicated in disease

...ing variants in gene sequences. These variants are strong candidates for functional studies to understand the role of variation in MHC-associated disease. Autoimmune disease affects about 3 million people in the UK. The three haplotypes studied here display different susceptibilities to diseases such as ty...

Pitt professor's theory of evolution gets boost from cell research

...the emerging understanding of cell structure lends strong support to Schwartz's theory of evolution, originally explained in his seminal work, Sudden Origins: Fossils, Genes, and the Emergence of Species (John Wiley & Sons, 2000). In that book, Schwartz hearkens back to earlier theories that suggest th...

Master genetic switch found for chronic pain

...n a piecemeal fashion, "Our data, however, provide strong evidence that Runx1 is required to specify the receptive properties of a large cohort of nociceptive sensory neurons." They also concluded that the dual functions they discovered for Runx1--controlling specification of sensory neurons and regulating ...

Low-cost drug gaining favor for use in HIV-infected children in poor countries

A new systematic review highlights strong results from a single study at the center of mounting support for worldwide use of the low-cost drug Bactrim to help HIV-infected children in poor countries. The reviewers surveyed medical literature on the preventive use of Bactrim -- one of severa...

2005 was the warmest year in a century

..., the warmest year of the century was 1998, when a strong El Nino, a warm water event in the eastern Pacific...e help of an El Nino. The result indicates that a strong underlying warming trend is continuing. Global warming since the middle 1970s is now about 0.6 degre...

Melanoma vaccine strategy shows promise in laboratory experiments

...the melanoma cells. "In our experiments, we saw a strong cancer-killing immune response when killer T cells are stimulated with this peptide," says Dorothee Herlyn, D.V.M., senior author on the study and a professor in the Immunology Program and Molecular and Cellular Oncogenesis Program at Wistar. "The re...

Genetic study shows humans have pushed orangutans to the brink of extinction

...shed in the open-access journal PLoS Biology shows strong genetic evidence of a catastrophic collapse in orangutan populations living in the fragmented forests of the Kinabatangan Wildlife Sanctuary in Sabah, Malaysia. Benoit Goossens, Lounès Chikhi, Michael Bruford, and their colleagues report that the ...

Evidence for omega 3 fats less conclusive than we thought, say experts

...and minimise bias. Pooling the results showed no strong evidence that omega 3 fats have an effect on total mortality or combined cardiovascular events. The few studies at low risk of bias were more consistent, but they also showed no effect of omega 3 on total mortality or cardiovascular events. When dat...

New RNAi tools enable systematic studies of gene function

...nt and cost-effective RNAi methods and we placed a strong emphasis on this part of the process," said David Sabatini, member of Whitehead Institute for Biomedical Research, assistant professor at Massachusetts Institute of Technology, associate member of the Broad Institute and a senior author. "In the ques...

Ernst Mayr's theory illustrated in genetic epidemiology studies

...opulation in a different direction. He saw a very strong interaction between natural selection and random f... be the limiting factors in an interaction system, strong genetic effects are observed only at APOE ?the rare component ?and not at LDLR ?the common component...

Male rivalry increases when females at most fertile, say researchers

...either high or low in dominant features, such as a strong jaw lines and thinner lips, were shown to male participants who provided ratings of dominance for each image. A dominant person was defined as someone who looked like they could 'get what they wanted'. Participants were asked to provide informati...

'Executive' monkeys influenced by other executives, not subordinates

...machinery that allows humans to empathize, to form strong social bonds, to do things like share food and to cooperate," he said. "Besides suggesting ways of diagnosing or assisting people with autism and other disorders, such studies are also a means of understanding what enables us to be social." ...

CU, USDA team to curb two invasive, poisonous vines

...y the plants' natural enemies. The plants contain strong poisons, which likely limit natural enemies. Deer and cattle do not eat them. Researchers also are finding that pale swallow-wort may be replacing milkweeds in open fields in New York state and across the Northeast coast, within the migratory range o...

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