Scientists map key landmarks in human genome
...ssing called "wavelet denoising" that revealed the striking patterns of positioned nucleosomes. On a graph, the data displayed as a series of peaks and troughs corresponding to positioned nucleosomes and nucleosome-free regions, respectively. Analysis revealed that promoters of genes that had similar expre...Inflammation may play role in metastasis of prostate cancer
...active nuclear IKKa. The researchers also found a striking elevation in expression of RANK ligand in late tumors, but it was not expressed by the cancer cells. Instead, it is expressed by invading inflammatory cells. Interference with RANK ligand production or activation, as well as interference with IKKa ...Finnish scientists discovered a new approach to treat virus-induced lymphomas
... Moreover, the researchers show that Nutlin-3a has striking anti-tumor activity in vivo in a mouse xenograft model for the PEL. Nutlin-3a treatment resulted in a marked regression of all tumors in the treated animals in two weeks. These results demonstrate that p53 reactivation via Nutlin-3a is an efficient t...Large size crucial for Amazon forest reserves
...mas Lovejoy and his Brazilian colleagues. The most striking result is that the effects of area on the occurrence of bird species are much stronger than the effects of isolation. "It is no surprise that small isolated fragments lack many species" said Ferraz. "Many birds are so uncommon that they will rar...Cocoa 'vitamin' health benefits could outshine penicillin
... of epicatechin, a compound found in cocoa, are so striking that it may rival penicillin and anaesthesia in terms of importance to public health, reports Marina Murphy in Chemistry & Industry, the magazine of the SCI. Norman Hollenberg, professor of medicine at Harvard Medical School, told C&I that ep...Lithium builds gray matter in bipolar brains, UCLA study shows
... "Bipolar patients who were taking lithium had a striking increase in gray matter in the cingulate and paralimbic regions of the brain," she said. "These regions regulate attention, motivation and emotion, which are profoundly affected in bipolar illness." While conventional MRI studies have measured bra...Technique monitors thousands of molecules simultaneously
...gton University's colors. This, Moeller said, is a striking image of the technique's ability to do chemistry at specific electrodes. "What electrochemistry does best is to reverse the polarity of things," Moeller said. "It takes things that are electron-poor and makes them electron-rich and vice versa; it can...Puzzling plankton yield secrets to role in evolution/global photosynthesis
...e and metabolic capabilities. "We found several striking features of genome organization," said DOE JGI’s Igor Grigoriev, the PNAS paper’s senior author. "Overlapping genes conserved across the species may enable them to cross-regulate their expression, while species-specific chromosomes with horizontally...Researchers demonstrate way to control tree height
.... Other than reduced size, there appeared to be striking variation in foliage color and leaf shape, some of which might have significant ornamental value. Root development also appeared to be very strong, which might provide increased stress tolerance and have value where extensive root development is need......th an array of different hormones. That revealed a striking influence of estradiol on back patterns. She also tested eggs from lizards captured in the wild and found a wide range of naturally occurring estradiol concentrations in the egg yolks. The researchers then performed experiments in breeding enclos...