Loosen leash on cancer protein 'watchdog,' researchers say
...eash on a watchdog. "p53 seems to be an important stress response gene that fights cancer when it works," Mendrysa said. "So we decided to see what we could do to increase p53's activity without completely cutting its Mdm2 leash." The scientists spent three years creating a strain of genetically modified ...Genes affecting blood pressure change as children become adults
... diet, physical activity, socioeconomic issues and stress ?and difficult to accurately measure, Dr. Snieder says. However, if factors negatively influencing blood pressure in blacks can be identified, it could contribute to solving health disparities such as blacks tending to have higher rates of hypertens...Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor
...ansport molecules necessary for protecting against stress into cells. When cells are stressed, they express more xCT on their surfaces. Of note, this sort of stress can be caused by KSHV itself. This suggests that the virus may facilitate its own infectivity and di...Plants used to detect gas leaks, from outer space!
...stressed", says Steven. "A satellite image of the stress responses in vegetation should identify gas leaks ...f CO2. When plant roots are starved of oxygen the stress caused to the plant can be quantified from the spectral quality of light reflected from the leaves, ...New crop of technology reveals plant health
...e system improvements will make the plants totally stress free, but if the project's crop management system takes off, at least their complaints will be heard and listened to. ...How nice, brown rice: Study shows rice bran lowers blood pressure in rats
...vels of a marker called 8-OHdG indicate biological stress and genetic damage due to oxygen-based free radica...the rats?levels of the peptide 8-OHdG. “Oxidative stress plays an important role in the initiation and progression of cardiovascular diseases,?explained lead...Oxidation defense in mosquitoes benefits malaria parasite
... one of the biochemical defenses against oxidative stress resulting from 3-hydroxykynurenine (3-HK) accumulation in mosquitoes and possibly other species as well. "3-HK is oxidized easily under physiological condition, stimulating the production of reactive oxygen species, which can damage cells," said Li. ...Just the expectation of a mirthful laughter experience boosts endorphins 27 percent, HGH 87 percent
... approach," he added. Earlier experiments showed stress reduction Berk said the results of this "anticipatory mirthful laughter experience, which is a kind of eustress or 'positive/good stress' event, builds on our earlier work and may constitute a real construct for what is the 'biology of hope.'" Ear...Researchers find molecular 'brake' to cell death
...cytoplasm, Tang says. "When we induced some cell stress and damage, the low levels of CC that came out from the mitochondria were ineffective because they are sequestered by an ocean of free nucleotides and ATP," he says. "No one had ever realized this kind of barrier existed to impede apoptosis." They f...Cincinnati surgeons report new treatment for often-fatal injury
...can work, says Dr. Giglia, but it puts significant stress on the patient's heart and brain and increases the risk for heart attack, bleeding, paraplegia and other problems. J. Keith Thompson, DO, and Amy Reed, MD, both of UC, were coauthors on this study. ...NASA study solves ocean plant mystery
...ankton are growing better. They are actually under stress and unhealthy. These conclusions solved the myster... "Because we didn't know about this effect of iron stress on the greenness of algae or phytoplankton before, we have always assumed that equally green waters ...Carnegie Mellon researchers discover new cell properties
...shell of a racquetball, which does not break under stress or force but can assume its original shape even after hard play." The researchers also think that the stiffer lamina in HGPS patients may be unable to communicate the proper biological signals to the DNA inside the nucleus to help the cell grow, whi...Iron critical to ocean productivity, carbon uptake
...t an indication of health, it was an indication of stress from a lack of iron." The study is also important...toplankton." Behrenfeld said the presence of iron stress in the ocean links phytoplankton to the climate through changes in terrestrial-based dust deposited ...Human behavior changes the number of strains of infectious diseases
...the assumption of monogamy is most applicable, but stress that their conclusions may have wider relevance. "There are implications for all sorts of other infections too," Eames continues. "Just think of the behavioral differences between village and city life: one with quiet streets and few new faces, and...How can identical twins be genetically different?
...tisol. This hormone is involved in the response to stress and also has anti-inflammatory effects. The discovery that 11â-HSD2 is over-expressed in patients may explain a common characteristic of RA patients. "It has been known for a long time that there is a deficiency of cortisol in RA patients," says Ho...Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
...is unique, being able to modulate both arousal and stress responses. So it could potentially be a target for drugs to treat anxiety and, interestingly, both insomnia and narcolepsy," he added. The receptor for NPS belongs to a class of those with similar structure called G protein-coupled receptors. Collec...Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's
...ave discovered a mechanistic link between cellular stress caused by free radicals and accumulation of misfol...a number of degenerative diseases and free radical stress in nerve cells," said Stuart A. Lipton, M.D., Ph.D., Professor and Director of the Del E. Webb Cente...Bt cotton in China fails to reap profit after seven years
...ld Bank, and Cornell professor David R. Just. They stress that secondary pest problems could become a major threat in countries where Bt cotton has been widely planted. Because of its touted efficiency, four major cotton-growing countries were quick to adopt Bt cotton: the U.S., China, India and Argentina,...Bones hold the key to blood renewal
...lease of stem cells into the blood in a variety of stress situations. This finding may have implications for bone marrow transplant techniques: The drugs given today to donors to increase the supply of stem cells in their bloodstream before they are harvested for transplantation cause the release of many ot...Magnetism and mimicry of nature hold hope for better medicine, environmental safety
...ent of dopamine and other biological indicators of stress and acute indicators of heart attacks are of particular interest to medical research. ...