Loosen leash on cancer protein 'watchdog,' researchers say
...ash." The scientists spent three years creating a strain of genetically modified mouse that only produced about 20 percent of the normal amount of Mdm2 protein, which is far less than they would have produced under ordinary conditions. The mice were created to answer a twofold question: Could increasing th...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...oft tissue infections are due to a single clone or strain of MRSA called USA300. As noted in the accompanying editorial, MRSA appears to have emerged as a cause of community-acquired skin infections in other U.S. communities as well. As noted by Dr. Blumberg and other Emory and Grady authors, "Empirical...ASU researchers find link between social behavior, maternal traits in bees
...a bee's reproductive status was more common in the strain of bees that preferred to forage for pollen (ident...ge hypothesized that that the high pollen-hoarding strain of social worker bees, although non-reproductive, represented the maternal, reproductive state of it...Finding a virus is not all bad news
...e to learn about the cat population. "Every virus strain has its own unique mutations and as the virus is passed from cougar to cougar these mutations in the virus accumulate, leaving a valuable trail of information about the host animal's relationships to each other. Because of the way the virus is transm...Salmonella bacteria use RNA to assess and adjust magnesium levels
... When Groisman and his colleagues created a mutant strain lacking the phoQ gene, though, they were surprised to find that production of the instructions to make the MgtA protein could still somehow respond to magnesium, producing less of its protein at high magnesium levels. Researchers used a computer pr...MIT researchers build tiny batteries with viruses
...ically, they manipulated the genes in a laboratory strain of a common virus, making the microbes collect exotic materials - cobalt oxide and gold. And because these viruses are negatively charged, they can be complexed between oppositely charged polymers to form thin, flexible sheets. The result? A dense, ...'Prosthetic' retinal cells let blind mice see light
...ensitive protein into "inner retinal neurons" in a strain of mice with photoreceptor deficiency that resembles the defect in such inherited human disorders as retinitis pigmentosa. Unlike the retinal rods and cones that normally function as light-sensing cells in the eye, these retinal neurons are normally ...APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal
...et up his lab at the CBR Institute and developed a strain of mouse that has fluorescent T-cells. "We are among a handful of labs which started to do this at the same time," von Andrian said of using the technology to study the immune system. The microscopes produce optical sections through solid organs, si...Cancer virus protein needed for successful infection
...re and a group of collaborators developed a mutant strain of HTLV-1 that lacked p13. The researchers then in... virus and a second batch of rabbit T cells with a strain of normal HTLV-1. Last, they inoculated six rabbits with T cells infected with virus that lacked t...Better beetle sought for salt cedar control
...tlatitudes," Michels said. "People have released a strain here or a strainthere, but what we want to do is r...s are adaptedto which latitude, he said. The Crete strain was released from Wyoming toSouth Texas and did not work everywhere. At the same time, some of these...Brittle prions are more infectious
... that result in different conformations. A similar strain phenomenon has been described for mammalian prions. More generally, even in noninfectious diseases involving protein misfolding, like Alzheimer's and Parkinson's diseases, the same protein can misfold into more than one shape with some forms being to.......' Some wounds often smell unpleasant ?an enormous strain on the patient. Yet honey helps here too by reducing the smell. 'Even wounds which consistently refused to heal for years can, in our experience, be brought under control with medihoney ?and this frequently happens within a few weeks,' Kai Sofka says...Human behavior changes the number of strains of infectious diseases
Simple models predict that only one strain of an infectious disease can exist at one time, but observation suggests otherwise. In a study in the August issue of The American Naturalist, Ken Eames and Matt Keeling (University of Warwick) use a mathematical model to help explain multiple strain...Genes discovered that allow gum disease bacterium to invade arteries
...ed in artery cells compared to a fully functioning strain of P. gingivalis. "Our study showed that all four mutated strains were defective in invasion of the artery cells and that their ability to survive inside of the cells was diminished. These results show that these four genes play a role in the inv...Mouse mimics chronic leukemia, will aid drug development
...tudy by cancer researchers here reveals that a new strain of mice offers the first real animal model for an ...changes that drive drug resistance. "This mouse strain shares many of the molecular and genetic features of human CLL, responds to drugs typically used to ...Scientists aim to thwart use of flu as bioweapon
...year. And wild birds infected with the deadly H5N1 strain of bird flu are gradually broadening the scope of that disease. This week in Rochester, scientists are discussing ways to better understand the flu and also how to prevent the possibility that terrorists could somehow modify flu as a bioweapon to mak...Friendly bacteria in chewing gum that bites back
...ly found in live yoghurt. BASF discovered a new strain of lactobacillus called L. anti-caries, which binds to Strepptococcus mutans, the bacteria responsible for tooth decay. S. Mutans sticks to the surface of teeth, where it produces an aggressive acid that breaks down the enamel. The friendly bugs in t...Ammonia-loving archaea win landslide majority
.... The gene was subsequently found in a marine strain of archaea that uses ammonia as its sole source of energy. Researchers examined soil samples from 12 pristine and agricultural lands across three climatic zones to see if such ammonia-oxidizing microorganisms were present in terrestrial ecosystems as...Ready, set, mutate?and may the best microbe win
...uñago and undergraduate Stephen Chen used a mutant strain of the microbe that was unable to make a key prote...d microbes competed for dominance. Eventually, one strain squeezed out almost all the competition by virtue of its ability to most efficiently metabolize food...Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
... true in other species, says Gourse, who studies a strain of E. coli that while harmless, is closely related... performed originally on this model organism." The strain that Gourse works with is one of the most well-studied species in biology and has important ties to ...