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Tag: "strain" at biology news

Fox Chase Cancer Center scientists identify immune-system mutation

...identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes,... the second time that a naturally occurring mutant strain has been found and bred at Fox Chase. In 1981, the laboratory group of Melvin Bosma, Ph.D., discover...

Scientists Replicate Hepatitis C Virus in Laboratory

...ion and production.?/p> The NIDDK group used a strain of HCV that would have applications to the greatest number of people ?genotype 1, the major type of HCV of human infections worldwide and the type most resistant to current therapies. They constructed an HCV replica using a DNA copy of the original H...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...arly a century since theidentification of a mutant strain of Drosophila fruit flies with“notched?wings in Thomas Hunt Morgan’s lab in 1910. Later studiesrevealed that the Notch gene encodes a receptor protein that extendsthrough both sides of the cell membrane and which is capable ofinteracting with a ligan...

Whole genome fine map of rice completed

...hole genome assembly and analysis for the maternal strain "PeiAi 64" (its main genetic background being Japonica, as well as a mixture of Indica and Japonica genes ). This would further help discovering distribution of the hybrid genes in F1 and the changes of physiological traits, thus revealing the source...

Scientists seek answers on what activates deadly anthrax spores

... The researchers are working with a non-pathogenic strain of anthrax. The genome sequences of four strains o...er closely related bacterium, Bacillus cereus, one strain of which can produce anthrax-like symptoms. The research team includes Conn Mallett, Ph.D., Derek P...

A bacterial genome reveals new targets to combat infectious disease

...e complete DNA sequence of the Wolbachia pipientis strain within Brugia malayi, a parasitic nematode responsible for lymphatic filariasis. This Wolbachia genome is small, only about a million base pairs, and many metabolically critical genes have degraded through mutation to the point of uselessness. This ...

Scientists decipher genome of fungus that can cause life-threatening infections

...thePresident of TIGR, deciphered the genome of one strain of C. neoformanswhile researchers led by Richard Hyman at Stanford University's GenomeTechnology Center in Palo Alto, CA, sequenced the second strain. Theproject was funded by the National Institute of Allergy and InfectiousDiseases (NIAID), part of ...

Scientists identify genetic pathways essential to RNA interference

...thor John Kim, PhD, and his colleagues developed a strain of C. elegans into which they added a gene that caused the worms to glow under ultraviolet light but also turned that gene off using RNAi. They then used RNAi to inactivate every one of the worms' 19,000 genes by feeding the worms bacteria that produ...

Scientists discover unique microbe in California's largest lake

... the National Academy of Sciences (PNAS)."This new strain of Acaryochloris is unique because it is able to l... Miller recalls."We purified the pigments from the strain and saw that they were verysimilar to those known from a species of blue-green algae calledAcaryochl...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

... that limit lifespan. The researchers developed a strain of dwarf rats that were naturally deficient in both growth hormone and in IGF-1. To mimic the rise in growth hormone and IGF-1 during adolescence in normal rats, some of these deficient rats were given growth hormone while they were between 4 and 14 ...

NYC's First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention

...new, rapidly-progressing and highly drug resistant strain of HIV in a New York man who progressed from his i...rred in mid-October 2004, to a largely untreatable strain of AIDS in just three months. According to City health officials, the man -- who had previously had...

NIAID Initiates Trial of Experimental Avian Flu Vaccine

..., M.D. “NIAID has supported research on H5N1, the strain responsible for this deadly form of avian influenza, since 1997 when the first cases in humans were reported. The initiation of this vaccine trial marks a key advance in our efforts to prepare to respond to an avian flu pandemic,?adds Dr. Fauci. San...

Study Models Impact Of Anthrax Vaccine

...could also prevent cases if anantibiotic-resistant strain of anthrax were used in an attack.“Our study highlights the need for rapid distribution of antibiotics tominimize casualties from an anthrax outbreak,?explained RonBrookmeyer, PhD, lead author of the study and professor in theDepartment of Biostatist...

The Bacteria's guide to survival

...mal N. gonorrhoeae to those infected with a mutant strain with defective pili, the researchers found a subse... cellular response to stress, including mechanical strain on the membrane. Also, a majority of these genes were known to be induced by a family of proteins ca...

Influenza vaccine uses insect cells to speed development

...l-based method, the time from receipt of the virus strain to the final vaccine product would be shortened to...to elicit an immune response against that specific strain of the virus. Wang and his colleagues have developed a methodology for rapidly producing and purify...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...o alcohol caused genes to be turned on more in one strain while decreasing expression of the same gene in th...showed different responses to alcohol in one mouse strain versus the other. As a result, Miles and his colleagues were able to formulate new hypotheses about ...

Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer

...n the surprising finding was made that the measles strain used internationally for vaccinations has natural anticancer activity. "But we had a concern that the measles virus may be a little too promiscuous in its ability to infect both cancer cells and non-cancer cells, so we wanted to develop a method whe...

Genetically modified rice in China benefits farmers' health, study finds

...rt of their acreage to a genetically modified rice strain and 37 farmers who planted all non-genetically modified rice. In 2003, because more insect-resistant rice seed had been distributed, the survey included 69 farmers who planted all OR part of their fields to genetically modified rice and 32 farmers wh...

Multiple Campylobacter Genomes Sequenced

... have completely sequenced the genome of C. jejuni strain RM1221 (isolated from a chicken carcass) and compared it with the previously sequenced C. jejuni strain NCTC 11168 and with the unfinished sequences of C. coli strain RM2228 (a multi-drug-resistant chicke...

Substance protects resilient staph bacteria

...ne development because the PGA is present in every strain of the organism," Dr. Otto says. "If a vaccine can...h catheters to demonstrate that the S. epidermidis strain deficient of PGA was not able to cause infection while the other strains containing PGA did. ...

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