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Tag: "stopping" at biology news

Dysentery uses 'sword and shield' to cause infection

...h causes dysentery, is able to invade cells, while stopping any response from the immune system. They found that shigella was able to infect cells by using a secretion system to inject proteins into human cells, (the sword), while lipopolysaccharide (LPS) on the surface of the bacteria acts as a shield to pr...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...ook for somethingelse? Hell no! Look out for whats stopping the drug! Perseverance issometimes worth it, as we can see .A new research study published in the January issue of Cancer Cellprovides exciting new information about how to boost the effectivenessof a promising cancer treatment that targets telomeres...

GATA: a graphic alignment tool for comparative sequence analysis

...ook for somethingelse? Hell no! Look out for whats stopping the drug! Perseverance issometimes worth it, as we can see .A new research study published in the January issue of Cancer Cellprovides exciting new information about how to boost the effectivenessof a promising cancer treatment that targets telomeres...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...alogues were between 91 to 99 percent effective in stopping the spread of breast cancer cells, the researchers report. Cell culture studies suggest they can reproduce that success in a wide range of other cancers, too. "What's unique about these analogues is that they do all this without affecting primary tu...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...an effectively shut down Ras' ability to function, stopping it from sending signals for uncontrolled growth." Initial experiments showed that knocking out the Icmt protein using genetic targeting also inhibited Ras, so the scientists decided to search for an effective and specific molecule that could inhibit...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...ed a new way of fighting antibiotic resistance: by stopping evolution. In the June issue of the open-access journal PloS Biology, the team describes how a protein called LexA in the bacterium Escherichia coli promotes mutations and helps the pathogen evolve resistance to antibiotics. The scientists also show...

While on trail of dioxin, scientists pinpoint cancer target of green tea

...wo bind, HSP90 no longer turns on the AH receptor, stopping the cascade of events that would lead to the activation of several harmful genes. This weekend Palermo is receiving the Wallace Fenn Award, named after a long-time physiology professor at the University of Rochester School of Medicine and Dentistry....

Pair of cancer genes found to drive both cell migration and division

...ity that interfering with them could be helpful in stopping the uncontrolled cell division found in cancers. Mutations in the genes, called PTEN and PI3K, already had been found in over half of all human cancers. "In cancer, you sometimes see cells failing to divide or undergoing unequal divisions. In additi...

Searching the depths of the straits of Florida for disease cures

..., just 30 miles away. Later, it became a notorious stopping point for narcotics smugglers, though regular patrols have all but eliminated that reputation. Though only about 50 miles from the Florida Keys, the Cay Sal Bank remains remote and relatively pristine because would-be visitors must clear customs on i...

Key to elephant conservation is 'in the sauce'

...nd that chilli peppers could be used as a means of stopping elephants from destroying crops in the Zambezi Valley, which straddles the borders of Zimbabwe and Zambia. While electric fences and other deterrents are prohibitively expensive, chillies provide farmers with a cost-effective means of warding off the...

The making and breaking of microtubules

...lowing down the transitions almost to the point of stopping them." Cryo-electron microscopy (cryo-EM) is capable of capturing such polymer structures without having to break them down and crystallize single subunits for x-ray diffraction analysis. X?ray diffraction might allow higher resolution, but it would...

A protein in the eye may prevent immune response and protect eyes from disease

...elieve that the protein F4/80 had a direct role in stopping immune response," says Stein-Streilein. Although the mechanism by which F4/80 stimulates the production of immune suppressing T Cells is unknown, the team believes that the protein may be involved in cell-cell communications. The presence of F4/80 ...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

...e defenses, preventing the immune system from both stopping the spread of virus and helping the body recover from infection. Interferon is so critical for recovery from these infections that it is being tested in clinical trials to treat infection with various flaviviruses. But the treatment appears to fail...

Secrets to antibody's success against West Nile Virus surprise scientists

...ies for related viruses that also are effective at stopping the process of infection after the virus attaches ...ells, while antibodies that were less effective at stopping infection could more effectively prevent the virion from binding to host cells. How does an antib...

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models

... "What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already been impaired, has now recovered," says Inde...

Researchers report breakthrough against world’s deadliest viruses

...ere could benefit from the vaccine development,"in stopping outbreaks where they originate as well as reducing the risk that these viruses will be used in bioterrorism." Colonel Erik A. Henchal, commander of USAMRIID, said the study illustrates the benefits of collaborative research to develop medical counte...

Variant prion protein causes infection but no symptoms

...enting prion diseases, shifting emphasis away from stopping the production of prion protein clumps and toward preventing interactions with prion protein anchored to cells, or learning to direct abnormal prion protein accumulations to specific parts of the brain where they will not produce symptoms. "Abnormal...

Study: Plants use dual defense system to fight pathogens

...duces a very strong immune response, in most cases stopping a would-be infection. "This work further suggests that plants use an active, complex immune system to combat pathogens," he said. "They have complicated surveillance systems that detect various infection-causing molecules and trigger defensive respo...

Drugs from the deep blue

...t could be useful in medicine -- killing microbes, stopping growth of cancer cells, or affecting the flow of calcium in and out of cells. Marine natural products are an eclectic mix of chemical types, drawing on all the pathways of metabolism, Molinski said. Some are related to fats and proteins; others incl...

Preventing a pandemic: Study suggests strategies for containing a flu outbreak

...e first time in human history, we have a chance of stopping the spread of a new influenza strain at the source through good surveillance and aggressive use of public health measures," said Katrina Kelner, Deputy Editor, Life Sciences, at Science. A rural Southeast Asian population is a likely place for the n...

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