Protein 'nanosprings' most resilient found in nature
...lso observed something unexpected: as long as they stopped stretching the molecules before they were completely unfolded, the extension was fully and immediately reversible. The ankyrin repeats showed no sign of wear after multiple stretch-relaxation cycles over a large range of applied forces, the team fou...International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy
...els of CD4+ cells has been stopped. Enrollment was stopped because those patients receiving episodic therapy had twice the risk of disease progression (the development of clinical AIDS or death), the major outcome of the study. NIAID made the decision to halt enrollment in collaboration with the study's Exe...Satellites show Amazon parks, indigenous reserves stop forest clearing
...ere 4 to 9 times higher. Indigenous lands clearly stopped clearing in high-deforestation frontier regions: 33 of 38 indigenous territories with annual deforestation greater than 1.5 percent outside their borders had inner deforestation rates of 0.75 percent or less. Few parks are located in active frontier...Taking a bite out of a fellow worker helps wasps recruit new foragers
...monitoring. "The rate of foraging slowed down and stopped completely, placing stress on the colony because materials the colony needs, primarily food, are not coming in. So the colony needs to recruit new workers to make up for the loss," O'Donnell explained. On the final day observers watched each colony...'Banana-jawed' fossil mammal linked to rare sound-producing skill
...al mandibular fenestra. But knowledge essentially stopped there, Simons said. Part of the problem was that today's hyraxes lack such skeletal features, so they offered little insight, he said. Also, relatively few Thryohyrax fossils had been found for study. Simons solved the supply problem as he collected...Pain killer fights breast cancer by targeting key enzyme
...s, scientists found that derivatives of nimesulide stopped the production of aromatase, the enzyme implicated...production in these cells. The nimesulide analogs stopped aromatase production in the breast cells, but not in the placental cells. "Aromatase is necessary f...Expert dispels bird flu paranoia
...and in droppings for four to five days, but can be stopped by heat, sunlight and most detergents. Authorities have confirmed the dangerous H5NI strain of bird flu in South East Asia, Russia and Eastern Europe but not in Australia. They fear an epidemic if this strain mutates to spread into a people-to-pe...Study shows combination of immune substances to be safe
...se of the study ?but the researchers found that it stopped disease progression in five of the patients for at least six months. "Our findings were encouraging," Carson says. "They indicate that we can safely administer IL-12 in combination with interferon, that it enhances the action of interferon in some ...In SAD patients, autumn antidepressants can prevent winter depression
...n was generally well tolerated. When the patients stopped taking bupropion extended release in the spring, there was no increase in the depression relapse rate compared with the placebo group. Patients with SAD have episodes of depression occurring in the fall and winter months. Although the cause is unkn...Cancer support cells may evolve, fuel tumor growth, study shows
...mor suppressor, p53, within the fibroblasts, which stopped this action. Thus, a change made only in epithelial cells had an impact on surrounding tissue cells. Next, the researchers showed that fibroblasts eventually lost p53 function. This resulted in cells continuing to divide and proliferate, thereby fu......subtle changes in the sequence. When these changes stopped the molecules binding, they knew they had a new linear motif. Now the lab will expand the method; Russell predicts that hundreds of linear motifs remain to be discovered. This has important implications for the study of genetic diseases. "A lot of w...Wild Gorillas Handy with a Stick
...nt of her.?Leah walked upright into the water, but stopped and returned to the edge when the water reached her waist. She then walked back into the water, grabbed a branch in front of her, detached it, and, grasping it firmly, repeatedly jabbed the water in front of her with the end of the branch, “apparentl...Shorter colds, milder flu may follow from newly revealed immune mechanism
...d CCL5 to ensure that the infection process can be stopped before it goes any further." Holtzman thinks the information about the role of CCL5 may lead to new methods to hasten recovery from respiratory viral inflections like influenza or the common cold, which at present have no pharmacological cure. CCL...'Nanospheres' that block pain of sensitive teeth
...ally blocked, the flow can be reduced and the pain stopped or significantly reduced. Currently, the only way to treat this condition is through good dental hygiene - using special toothpastes and fluorine mouthwashes which encourage re-mineralization of the dentine coating. Jonathan Earl, David Wood and St...PLoS Medicine publishes first trial of effect of male circumcision on HIV infection
...cal to continue the study. The trial was therefore stopped and the uncircumcised men were offered circumcision. The trial, results of which were first reported at an international AIDS conference in July, has attracted huge attention among the global health community. Bertran Auvert and his co-authors h...Anthrax stops body from fighting back, study shows
...ls, Southwick said. Low doses of the lethal toxin stopped the protein actin from building filaments to steer the neutrophils, stopping the body's immune response, the study found. "Neutrophils crawl around in the body and roll around in the bloodvessels and whenever they sense bacteria, they gobble it up l...An essential regulator of body weight revealed
...n to eat less and less; by the fifth day, they had stopped eating entirely. Within 6-8 days, they had lost 20 percent of their body weight. Interestingly, the researchers found that if they administered the toxin when the animals were less than eight days old, while NPY/AgRP neurons were still developing an...Micro RNAs play role in egg making
...two groups, the researchers discovered that miRNAs stopped the manufacturing of a small group of key proteins, including ones that produce ribosomes. These structures constitute the cell's protein-making machinery, and their shutdown would render cells unable to produce new proteins. The investigators also ...Breast tumors in mice eradicated using cancer vaccine
...mor from growing out to 100 days, at which time we stopped measuring since this is a long time for experiments of this type," says Paterson. "The tumors stopped growing or went completely away." The researchers published their findings in the September 15 issue...President Bush's cut to AIDS prevention in Africa would be devastating
Twenty-eight years after intense selective logging stopped in the region now known as Uganda's Kibale National Park, the red-tailed guenon (Cercophithecus ascanius) is a primate still in decline. The logging practice, scientists report in a new study, changed the ecological balance for these monkeys, leading...