Research holds promise for herpes vaccine
...fection in animals, but the spread of the virus is stopped long before disease can occur. "In short, we can disarm the virus such that it is absolutely unable to cause disease, but is still remarkably potent as a vaccine," Halford said. In a human vaccine, the genetic instructions for ICP0 would actuall...Male circumcision reduces HIV risk, study stopped early
A University of Illinois at Chicago study has been stopped early due to preliminary results indicating that medical circumcision of men reduces their risk of acquiring HIV during heterosexual intercourse by 53 percent. The study's independent Data Safety and Monitoring Board met Dec. 12 to review the interi...Brains can recover from alcoholic damage but patients should stop drinking as soon as possible
...e alcoholics, who had no complicating factors, had stopped drinking alcohol. It was carried out in collaboration with colleagues from the University of Oxford’s Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB) and from the University of Siena’s Institute of Neurological and Behavioural S...... only if almost all travel between cities could be stopped almost as soon as an outbreak was detected in each city. It would be more effective to take other measures that would control the spread of the virus locally. These measures could include use of vaccines and antiviral drugs if they were available and...Scientists discover new regulating mechanism in cells
...ut the RHA protein and learned that the retrovirus stopped making several vital proteins. "That suggests that the retrovirus needs RHA to make these essential proteins," says Boris-Lawrie, "and that means RHA is a potential target for antiretroviral therapy." The researchers also learned that when RHA is...No cell walls, no new cancer cells
...equired for new cell walls. "In fact, we literally stopped the cell cycle in its tracks by removing SREBP1 from cells. It seems that if you don't have SREBP1 activity, you can't make lipids, and if you don't have lipids, you can't make new cells." According to Dr. Ericsson, who is also a Research Fellow o...Defense peptide found in primates may block some human HIV transmissions
...ved 7 million years ago, the more advanced species stopped making a protein that University of Central Florida researchers believe can effectively block the HIV-1 virus from entering and infecting blood cells. HIV-1 often mutates quickly to overcome antiviral compounds designed to prevent infections. But a...Quitting smoking improves lung function considerably
...se who quit. Of the 10 subjects who successfully stopped smoking and completed the six-week study, five used nicotine patches, one employed acupuncture and four quit without any aid. The researchers believe that their findings highlight the importance of smoking cessation for adults with asthma. ...Spinal cord bridge bypasses injury to restore mobility
...ished, for the first time, by using an enzyme that stopped growth inhibitory molecules from forming in the small scar that forms at the exit ramp of the bridge, where it is inserted into the spinal cord on the other side of the lesion. This allowed the growing axons to reconnect with the spinal cord. Jerr...Scientists stop autoimmune disease without shutting off immune system
...om damaging the skin as they normally do. The drug stopped a series of cell-signaling events that lead to the loss of adhesion or "stickiness" between skin cells. Thus, it stops the disease without affecting the immune system. "There are a number of companies developing inhibitors of the p38 enzyme for tre...Toxic molecule may cause most common type of muscular dystrophy
... abnormalities. When doxycycline was stopped, mice stopped producing toxic RNA and returned to normal, except in cases when the heart was severely damaged. So far, however, Mahadevan and other scientists can't explain exactly what happens inside the cell to cause someone to get myotonic dystrophy. "The p...Atmospheric ozone recovering in mid-latitudes, report shows
...e study's data indicate that atmospheric ozone has stopped decreasing in one region and is actually increasing in the other of the two most important lower regions of thestratosphere. Scientists attribute the stabilization of ozone levels in the past decade in the 11- to 15-mile (18- to 25-kilometer) altitu...More evidence mammals, fruit flies share make-up on function of biological clocks
...vels. In both cases, they found that the clock had stopped ?with high levels of clock gene expression when Cry was mutated, and low levels when Cry was over-produced. These results indicated that Cry normally inhibits clock gene expression in many clock cells ?just as it does in the mammalian clock. "In a...Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
... such as those delivered by defibrillators usually stopped aberrant waves, in some cases they cause them to accelerate and multiply. The Duke University and Johns Hopkins University team, led by Nenad Bursac of Duke's Pratt School of Engineering, reported its findings in the Feb. 1, 2006, Cardiovascular Res...Molecular force field helps cancer cells defend against attack
...th VEGFR-3 by introducing a different protein that stopped cancer cells from dividing and caused them to die but spared normal breast cells. "FAK is a critical molecule, and in the future different ways of targeting either the enzyme itself or targeting the binding between these various proteins will have a...Dogs keep dying: Many owners unaware of toxic dog food
...tealing food from the kitchen counter. Others just stopped eating the food and begged for treats. Unfortunately, some owners used gravy and other mixers to entice their dogs to consume what they thought was safe, quality dog food." "It's devastating to dog owners who feel responsible for poisoning their bel...Worm hormone discovery may aid fight against parasitic disease
...ture the ligand, however, the mutants' development stopped before they reached maturity. Instead, the worms went into a "resting" stage called the dauer diapause, in which they don't eat or reproduce. When the researchers provided the mutants with the missing ligand, it prevented the dauer stage, and the ani...Movement of chromosome in nucleus visualized
...ducing a mutant actin that does not form filaments stopped the movement, while the introduction of an actin m...as added to the cells, the chromosome movement was stopped completely. These experiments conclusively established that actin and myosin are involved in this ch...Single microRNA causes cancer in transgenic mouse
... revealed that the B cells in enlarged spleens had stopped evolving in the pre-B phase, right at the point where a B cell normally begins to create structures necessary for antibody development. "We believe that miR 155 initiated the process that blocked further differentiation of these cells," says Costin...Rhinos clinging to survival in the heart of Borneo, despite poaching
...ve a healthy future in Borneo the poaching must be stopped immediately. Their numbers are so small that losing one or two rhinos to a poacher could upset the remaining rhinos' chances of survival," said Sybille Klenzendorf, lead biologist of WWF's Species Conservation Program. "Conservationists and Sabah g...