A gene's first 'kiss' sets off that affair known as puberty
...shion. With each secretion, the pituitary gland is stimulated to secrete its own messengers, lutenizing hormone ...inistered to male monkeys, LH, one of the hormones stimulated by GnRH secretion, was no longer dormant, with levels 25-times higher than its baseline of zero. In...Jump-starting T Cells In Skin Cancer
... get activated, Coulie thinks that the few T cells stimulated by the vaccine may change the local, suppressive environment of the tumor such that other T cells can snap out of their stupor and attack the tumor. ...Controversial drug shown to act on brain protein to cut alcohol use
...scientists confirmed in a cell model that Ibogaine stimulated GDNFactivity. Finally, they showed that a known inhibitor of GDNF blockedIbogaine's ability to decrease alcohol craving in the rats, suggestinga direct link between Ibogaine's desirable actions and GDNF."If we can alter the GDNF pathway, we may well ...Research on Worms Yields Clues on Aging
...ives.Further tests showed that the anticonvulsants stimulated transmissionof signals in nerves that control body movement.Scientists previously had found genetic mutations in C. elegans thataffect both the nervous system and life span. The researchers usedthese mutant worms to further pin down the mechanism by ...Jefferson Virologists Coax HIV Out of Hiding
...ells with severaldifferent drugs to determine what stimulated the latent virus the best.“To our surprise, it was...ly asub-population of blood cells, lymphocytes not stimulated by IL-2 orOKT3. There could be other reservoirs as well.?Ultimately, he says, the answer to the late...In the sea slug's defense against lobsters, confusion is key
... successful evasion. Because the set of behaviors stimulated by the slug's secretions resemble activation of a feeding pathway, the researchers named this novel chemical defense "phagomimicry." The stickiness of the slug's secretions appears to contribute to long-lasting effects on the target despite the aqueo...New research questions basic tenet of neuron function
...s in two different "modes" ?one when the neuron is stimulated and actively relaying a message, and the other through spontaneous release when the neuron is "at rest," or inactive. Until now it was believed that the same synaptic vesicles were responsible for releasing neurotransmitters in both modes. However, ...Genetically modified natural killer immune cells attack, kill leukemia cells
...IL-15. The genetically modified K562 cells quickly stimulated the expansion of the NK cell population to more than10,000 times their original number. The technique triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cell...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...at lets the cell recognize a specific target. When stimulated to multiply, each of those cells produce an army of immune cells against their designated target. Specific infectious organisms or other foreign substances stimulate T cells to divide and multiply in order to form an attacking army. However, the sjT...NJIT Presidential Award winner takes stem cell research another step
...culture studies. Both showed that the biomaterials stimulated stem cells, producing new bone tissue and fully repairing the rats' bones. Arinzeh's second stem-cell discovery proved that adult stem cells taken from one patient can be successfully implanted in another. Researchers originally thought such a trans...LUCA technologies confirms real-time methane generation
...ng that methane formation by these microbes can be stimulated by the introduction of nutrients or suppressed by heat sterilization or the introduction of oxygen, Luca has shown that radio-labeled CO2 (carbon dioxide) introduced to these substrate samples is converted to radio-labeled methane. This demonstrates ...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
...: "Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol" Publishing in Cell Metabolism, Volume 1, Number 3, March 2005, pages 179-189. www.cellmetabolism.org ...Single stem cells from bone heal a broken heart
.... This improved cardiac function because the cells stimulated release of growth factors and anti-apoptotic agents that, in turn, increased the proliferative potential of cardiomyocytes and enhanced survival of host myocardium. This is the first report of endogenous cardiomyogenesis after adult human stem cell t...Revolutionary nanotechnology illuminates brain cells at work
...er the microscope by watching the color change. We stimulated the neurons and watched them secrete glutamate in response. We also saw the removal of the glutamate as the neurons returned to normal ready to fire again." "This is a tremendously exciting technology," remarked Wolf Frommer, leader of the FRET team...Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
...IL-15. The genetically modified K562 cells quickly stimulated the expansion of the NK cell population to more than10,000 times their original number. The technique triggered growth of NK cells specifically, which greatly simplified the ability of the researchers to collect a pure population of these immune cell...NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells
... the cell the vesicles were stored and how insulin stimulated them to fuse with the cell membrane. In the current study, the NIH researchers observed fat cells taken from mice and learned that the GLUT 4 vesicles are highly active. They discovered that, although a few vesicles are scattered throughout the cell...Scientists discover that three overlapping signals in embryo help get the backbone right
... basically naïve cells that, theoretically, can be stimulated to become any tissue of the body. In fact, the proteins normally used by the embryo have recently been put to use in embryonic stem cell work. Noggin, one of the proteins isolated by the UC Berkeley research group, has been used in cultures to maint...Two chemicals boost immune cells' ability to fight HIV without gene therapy
...e enabled the immune cells to divide indefinitely, stimulated their production of a viral-fighting molecule and prolonged their power to kill HIV-infected cells. In this study, the scientists isolated immune cells from the blood of HIV-infected persons and cultured the cells with the chemical compounds. They w...Structure-building cell signals also may influence learning and memory
...ing chemical pathway was triggered that ultimately stimulated an enzyme called synaptojanin-1. This enzyme is essential for a process known as cellular endocytosis, whereby certain chemicals, viruses or other agents are surrounded with a snippet of the cell's membrane. Endocytosis important as it is the process......e, suggesting that stem cell repopulation might be stimulated by greater degrees of injury to the lung. The possibility that the presence of male gender pneumocytes in female lungs might result from an earlier pregnancy with a male fetus cannot be ruled out, Zander said. However, the association between the nu...