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Tag: "stick" at biology news

Common cancer gene sends death order to tiny killer

...uctions to make proteins. Once produced, microRNAs stick to messenger RNAs and, like crumpled paper jammed in a copy machine, prevent proteins from being made. Josh Mendell, M.D., Ph.D., an assistant professor in the McKusick-Nathans Institute of Genetic Medicine, suspected that p53 activates microRNAs...

An 'elegant' idea proves its worth 25 years later

...sease where patients come in near-comatose and you stick a needle in them and lo and behold, they wake up—just like that. It was just astonishing," he says. "His elegant idea was to give patients chemicals they already make in small amounts in large doses to make up for the missing urea cycle enzyme th...

Toxoplasmosis infection trick revealed by scientists

...urface of the host cell, assisting the parasite to stick to, and then enter the human cell. Using a novel carbohydrate microarray the team were able to identify the precise sugars to which the parasite protein binds. Following this the team used a combination of NMR spectroscopy and cellular studies to...

Growing nerve cells in 3-D dramatically affects gene expression

...ss incubators, better known as petri dishes, cells stick to the bottom and spread out as they multiply. But in the body, cells don't grow that way. They are suspended in fluids and gels and surrounded by other cells. And these cells aren't stuck; they move. As a result, some scientists suspect that hoth...

Rapid oral HIV test shows great promise according to MUHC-led research

...d (saliva) and the other from a blood-based finger stick - with traditional blood tests. They demonstrated that the oral fluid test had 100 per cent accuracy versus the finger-stick blood test, which showed one false positive (99.7 per cent specificity). There was little reported discomfort during sample c...

Renegade RNA -- Clues to cancer and normal growth

...t's why normally microRNAs always have appeared to stick close to the cell's protein-making machinery. But during a survey of more than 200 of the 500 known microRNAs found in human cells, Mendell's team discovered one lone microRNA "miles away" --- in cellular terms --- from all the others. "It was...

Cancer-killing invention also harvests stem cells

...is labmates discovered that bone marrow stem cells stick to adhesive proteins called selectins more strongly than other cells -- including blood cells -- stick to selectins. When King came to the University of Rochester in early 2002, he started studying the ...

A rarity among arachnids, whip spiders have a sociable family life

...ers caress their young with long feelers, siblings stick together until they reach sexual maturity, and all mix in social groups. This is surprising behavior for these arachnids long-thought to be purely aggressive and anti-social, according to a Cornell researcher. Social behavior is extremely rare in a...

New molecular pathway could reveal how cells stick together

... to fill in the details behind how cells decide to stick to a surface, which could lead to a better understanding of the importance of this pathway to the physiology and development of organisms. Cells must interact with each other to produce system responses, like the remodeling of a tissue during develo...

Eating less salt could prevent cardiovascular disease

...o had cut back on salt during the trials tended to stick to a lower salt diet compared to those who had been in the control group. In total the researchers obtained information from 2415 (77.3%) participants, 200 of whom had reported some sort of cardiovascular problem. The reduction in the risk of de...

Targeting tumors the natural way

...nly weakly to any single target receptor, and thus stick to cells only when several receptors are displayed together. These weak "multivalent" interactions cut down on cases of mistaken identity, because if the agent contacts the wrong cell type, it can be easily displaced. The team got the idea to mimi...

Bacterial response to oxidation studied as toxin barometer

... said. “So we can measure oxidative damage when we stick the sensor in the water, not individual concentrations of individual chemicals. It also announces the presence of an oxidative toxin you haven’t identified.? “We don’t have to have 20 sensors for 20 toxins. We can sense the presence of any oxidativ...

Coated nanoparticles solve sticky drug-delivery problem

...udies indicated that even if nanoparticles did not stick to the mucus, they might have to be smaller than 55 nanometers wide to pass through the tiny openings in the human mucus mesh. (A human hair is roughly 80,000 nanometers wide.) Using high-resolution video microscopy and computer software, the researc...

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

... coated with various marker molecules to make them stick selectively to tumors and other targets within the body. The particles can also be made to carry anti-cancer drugs or radioactive materials directly to a tumor. Magnetic nanoparticles designed to attach to cancerous tissue can also be made to heat up...

ASU researchers test antibacterial effects of healing clays

... the charged cations, for example, potassium, that stick to the negatively charged tetrahedral ring surface. And the jelly? Organic compounds or other species of any or no charge are possible. This interlayer, as the peanut butter and jelly are termed, can vary in width and composition depending on the kin...

One-of-a-kind imaging probe reveals secrets useful for drug discovery

...equired hundreds of milkings to get enough walking stick venom for analysis. We were able to get great data...cial probe to examine the venom, which the walking stick sprays to defend itself from predators. Similar to the magnetic resonance imagers used to examine ...

Selecting life: Scientists find new way to search for origin of life

...sorbed molecules. To discover "which molecules stick and which don't," as Hazen says, the Carnegie scientists are also collaborating with a team at the Smithsonian Institution led by Edward Vicenzi to employ a workhorse of chemistry called Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS). The ...

Archerfish tune their shots to universal properties of prey adhesion

...n animal's adhesive force--its natural tendency to stick to a surface--is closely proportional to the animal's size. The researchers showed that for any given size of prey, the archerfish tune their attacks such that prey are hit with about ten times the force that adhesive organs of animals of that si...

Lab-on-a-chip could speed up treatment of drug-resistant pneumonia

...the current version of the chip -- and are made to stick to a bacteria-friendly surface using an electric c...at will allow virtually all pathogenic bacteria to stick to it, the company has so far focused on nine bacterial species that cause most of the cases of drug...

Engineer ramps up protein production, develops versatile viral spheres

...aces. Theamino acids allow the capsids to either stick to and carry specific proteins orstick to other capsids, allowing their assembly en masse. The tiny spheres could therefore transport targeted vaccines or medicines around the bloodstream or could be linked together in different configurations to mak...

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