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Tag: "steroid" at biology news

Nanoparticle Breast Cancer Drug Approved by FDA

...s associated with solvents and will no longer need steroid premedication when they receive this albumin-bound form of paclitaxel," said principal clinical study investigator William J. Gradishar, M.D., associate professor of medicine, division of hematology/oncology at Feinberg and co-director, Lynn Sage Bre...

New Lab Research May Help Those Deafened By Immune System Attack

...get part or all of their hearing back if they take steroid medicines, but many are left to cope with partial ...nts experienced improvement in their hearing after steroid treatment, and 35 did not. But the vast majority, 89 percent, of those who improved had a positive i...

Clear rules needed to govern deep sea bioprospecting: UNU

... on derivatives of a sponge while a sponge-derived steroid compound completed phase one US trials as an asthma drug in 2000. Other research in progress includes treatments for breast and ovarian cancer. Impediments to this research include not just the high expedition costs but the absence of clear rules go...

A Father’s Day Gift: Free DNA Paternity Testing

... on derivatives of a sponge while a sponge-derived steroid compound completed phase one US trials as an asthma drug in 2000. Other research in progress includes treatments for breast and ovarian cancer. Impediments to this research include not just the high expedition costs but the absence of clear rules go...

Scientists find a maturity gene in fly

...2 years of life and then, suddenly, in response to steroid and thyroid hormones and their receptors [molecule... genes that control metamorphosis in response to a steroid hormone named ecdysone, which is emitted by a gland as the larval stages end. When the gene was disa...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

...2 years of life and then, suddenly, in response to steroid and thyroid hormones and their receptors [molecule... genes that control metamorphosis in response to a steroid hormone named ecdysone, which is emitted by a gland as the larval stages end. When the gene was disa...

Pillows - a hot bed of fungal spores

...romised patients such as transplantation, AIDS and steroid treatment patients are also frequently affected with life-threatening Aspergillus pneumonia and sinusitis. Fortunately, hospital pillows have plastic covers and so are unlikely to cause problems, but patients being discharged home - where pillows ma...

Leading lampreys to slaughter: Pheromone for scourge of Great Lakes identified

...eromone and synthesized the principal one, a novel steroid akin to a shark steroid that possesses anticancer activity. This is the first migratory attractant to be identified in any f...

Jefferson scientists identify gene defect leading to abnormal skin development and cancer

...eromone and synthesized the principal one, a novel steroid akin to a shark steroid that possesses anticancer activity. This is the first migratory attractant to be identified in any f...

Animal models show that anabolic steroids flip the adolescent brain's switch for aggression

...reatments for aggressive behavior, with or without steroid abuse. "Linking aggression to fluctuations in vasopressin makes it an important neurotransmitter to target for pharmacotherapy," he says. ...

Absence of critical protein linked to infertility

...s determined that C/EBPb is a critical mediator of steroid hormone responsiveness in the uterus. "This gene is expressed when the uterus is ready for embryo attachment," said co-author Indrani C. Bagchi, a professor of veterinary biosciences in the College of Veterinary Medicine at Illinois. "Its presence i...

New brain hormone puts brakes on reproduction

... hormones stimulate production of estradiol, a sex steroid hormone and the body's main form of estrogen, and regulate ovulation, the production of fertile eggs. Estradiol and testosterone, in turn, feed back on the pituitary to shut down production of pituitary hormones, establishing feedback that keeps the...

Uncovering sex-change secrets of black sea bass

...strogen plays the major role, he said. In males, a steroid hormone called 11-ketotestosterone is involved. The scientists are now studying those hormones as well as the enzymes that control them. By turning off estrogen production, Berlinsky says, he can turn a female fish into a male within a week. Giving...

New genes implicated in rheumatoid arthritis

...-hydroxysteroid dehydrogenase type 2 (11ß-HSD2), a steroid pathway enzyme linked to inflammation and bone erosion. This gene was also found over-expressed in the synovial tissue of OA patients. The third most significantly over-expressed gene was cysteine-rich, angiogenic inducer 61 (Cyr61), well-establish...

No-mow grass may be coming to your yard soon

...eciphered the signaling pathway for a key class of steroid hormones that regulates growth and development in plants. "By manipulating the steroid pathway…we think we can regulate plant stature and yield," said Joanne Chory, a Howard Hughes Medica...

Salk scientists untangle steroid hormone signaling in plants

When given extra shots of the plant steroid brassinolide, plants "pump up" like major league b...eir findings in this week's journal Nature. "The steroid hormone brassinolide is central to plants' growth. Without it, plants remain extreme dwarfs. If we a...

Ozone recovering, but unlikely to stabilize at pre-1980 levels, says study

When given extra shots of the plant steroid brassinolide, plants "pump up" like major league b...eir findings in this week's journal Nature. "The steroid hormone brassinolide is central to plants' growth. Without it, plants remain extreme dwarfs. If we a...

Researchers find docking sites for glucocorticoid receptor and Hsp90

...nteractions that regulate the response of cells to steroid hormones. The discovery, they say, could lead to new ways to boost the effectiveness and reduce undesired side effects of steroid-hormone treatments and cancer drugs. The study, published online this week ahead of regular publication in the Procee...

SARS: No evidence that any of the treatments worked

...gs in patients were inconclusive. Of 29 studies on steroid use, 25 were inconclusive and four found that the treatment caused possible harm. From the published studies, it is not possible to say whether any of the treatments used against SARS were effective. It is now many months since any new cases have be...

Mutant gene causes severe kidney disease in infants

...t nephrotic syndrome who nevertheless responded to steroid treatment," says Friedhelm Hildebrandt, M.D., the U-M's Frederick G L Huetwell Professor for the Cure and Prevention of Birth Defects. "The early onset form of the disease is severe and infants often go into end-stage renal disease within the first y...

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