Walking not enough for significant exercise benefits
...ink what matters most is the total number of daily steps accumulated, and not pay much attention to the pace or effort invested in taking those steps," Dr. Harber said. "The 10,000-step or pedometer-based walking programs are great for people--they are motivating, and provide an excellent starting point fo...Advance helps explain stem cell behavior
... "It's clear that there is an extended sequence of steps which turn some genes on and others off, allowing ... that simulates all of the complex and interactive steps in this patterning process, Gross said. Much of this process happens during a surprisingly short t...Two-faced protein can stop metastasis or promote it, researchers say
...l of Cell Biology, helps illuminate the very first steps involved in metastasis, the spread of cancer that makes the disease difficult to treat, and suggests that a future designer drug might be able to block the beginning of this dangerous process, or stop it once it starts. "Our data show that this on...MIT designs portable 'lab on a chip'
... electro-osmotic pump, tiny electrodes with raised steps generate opposing slip velocities at different heights, which combine to push the fluid in one direction, like a conveyor belt. Simulations predict a dramatic improvement in flow rate, by almost a factor of twenty, so that fast (mm/sec) flows, compar...Newly discovered behavior in cancer cells signals dangerous metastasis
...cells, Garcia-Blanco said. Identifying the various steps that occur during the natural progression of tumors could lead to therapies for blocking metastasis, he said. ...Scientists find mutations that let bird flu adapt to humans
...ze the topography of human cells, but they are key steps on that pathway. More mutations, says Kawaoka, will be required for the virus to fully adapt to humans, but it is not known how many mutations are needed for such a change. However, if scientists are able to continue to monitor and secure viral is...Mayo discovers protein as potential tactic to prevent tumors
...aired, our studies show that CDK2 can initiate the steps necessary for cells to order the production of genes involved with cell death, and the errant cell dies without propagating its damaging genetic message to progeny cells of its own." "As patients and their physicians seek to control or cure tumors...T for two: Scientists show how immune system chooses best way to fight infection
...ory damage to the body. This may be one of the key steps in preventing the mother from rejecting the foetus growing inside her." ...Lab-on-a-chip could speed up treatment of drug-resistant pneumonia
...ess than eight hours. One of the most difficult steps was to design a surface that would be hospitable to the bacteria but that would at the same time keep the antibodies and antibiotics from sticking to it, Lochhead said. While Accelr8 is working on finding a "universal" material that will allow virtua...Computer scientists unravel 'language of surgery'
... surgical tasks, Hager said, unfold in a series of steps that resemble the way that words, sentences and paragraphs are used to convey language. "In speech recognition research, we break these down to their most basic sounds, called phonemes," he said. "Following that example, our team wants to break surgi...Rescuing injured hearts by enhancing regeneration
...se, you don't get blood vessels." Two important steps are needed to turn these findings into a treatment, Engel says. First is to show that the treatment works when not given immediately after the heart attack, since many people sustain progressive damage to their hearts from repeated minor infarctions...BC catalyst discovery promises faster, cheaper drug production
...st that will eliminate several costly and wasteful steps from the process of synthesizing certain molecules...f the new catalyst, what used to take four to five steps to accomplish ?each step adding significantly to the final cost ?can now be achieved in a single tra...Nature's process for nitrogen fixation caught in action
...research method resulted in the ability to witness steps in the biological process that enables some microorganisms to convert atmospheric nitrogen to nutrients. The research is reported in the Proceedings of the National Academy of Science (PNAS) Special Feature Issue on Nitrogen Fixation, in the invit...Selecting life: Scientists find new way to search for origin of life
...rs ago. Scientists understand several probable steps in the origin of life, notably how the first organ...ctions are the most likely candidates to the first steps to life. "Crystal surfaces are complicated," Hazen continued. "They have crevices and craters, a...Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia
...n a half-century. They also have known some of the steps by which lysine is produced in plants, but they di... 1950s, and so he had intimate knowledge about the steps of the pathway," said Leustek. "And he's the one that alerted us to the fact that plants do it diffe...Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration
... can be successful." Swaroop sees several next steps in his quest to find treatments for retinal and ma...the next five years we will begin to see the first steps toward retinal cell transplants for people with blinding eye disease," says Swaroop. ......t is a very stable process and many of the crucial steps associated with it have remained the same along the vertebrate evolutionary pathway. But at the same time there's evidence of instability in other areas. According to Dr. Evsikov, "There's tantalizing evidence for rapid change in a few critical mam...Solution to bacterial mystery promises new drugs
... use PlsY to transfer the fatty acid to G3P. These steps initiate membrane phospholipid formation required for cell growth. "Our discovery of PlsX and PlsY not only solved a troublesome mystery," Rock said. "It's also important because identifying the essential components required for disease-causing bact...Molecular atlas provides new tool for understanding estrogen-fueled breast cancer
...iven tumors. "For the most part, the sequence of steps between the activation of the estrogen receptor and the beginning of tumor cell division has been unclear. We've known of only a handful of the portions of genes that bind to the ER -- the so-called control regions that activate or deactivate the gen......ubes," Becker explains. "This is the first of many steps in the critical goal of reducing health risk by de novo engineering of the nanotubes themselves." ...