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Tag: "step" at biology news

Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...ellon. “This helps membranes to curve, a necessary step for HIV to fuse with an immune cell as it infects it.” The Carnegie Mellon scientists used X-rays to study how HIV fusion peptide (part of a larger protein) affected the energy of manufactured lipid bilayers made to mimic normal cell membranes. Lipi...

FDA sees nanotech challenges in every product category it regulates

...ologies Director David Rejeski, “Today, FDA took a step forward in fulfilling its responsibilities for nanotechnology oversight. If nanotechnology regulation was a baseball game, FDA has scored the first run in the first inning. But the agency must act rapidly to adopt and fully implement the Nanotechnolo...

Threats to wild tigers growing

...t "tiger ambassadors" to advocate for the species, step up efforts to prosecute poachers, and provide economic incentives to encourage conservation. ...

Old memory traces in brain may trigger chronic pain

...an said. Based on the animal results, the next step will be to test the drug in clinical trials, Apkarian said. “When we do this in a clinical trial, we expect people to say I still have the pain, but it’s not bothering me anymore,” Apkarian said. “We think they will have a physical awareness of t...

Simulations unravel outer membrane transport mechanism

... time scale: femtoseconds,” Tajkhorshid said. Each step relies on the completion of a previous step, so the simulations take an extensive amount of time and considerable computational effort. The researchers addressed two key questions: First, could the bond between TonB and the luminal domain withstan...

Studies to find better ways to preserve human eggs, ovarian tissue under way

... If all goes as hoped with this study, the next step will have Drs. Song and Emmi taking ovarian tissue from cancer patients, vitrifying it then, after they are sure it’s cancer-free, re-implanting it when the woman is ready. A concurrent phase I study is comparing standard cryopreservation to vitr...

In mice, drug protects against diabetes and atherosclerosis

...igil said that this remains to be proven. The next step is to perform more detailed toxicity tests in animals, and then move toward human testing. The important lesson from the new study, the researchers wrote in their report, is the demonstration that aP2 can be blocked by a small-molecule, oral compo...

Brightening prospects of using fluorescent nanotubes in medical applications

... Hertel’s team is currently working on the next step necessary for many biomedical uses: finding a way to attach molecules to the surface of the nanotubes that will allow them to bind to specific biological targets. The trick is to do so without dimming or extinguishing the nanotubes’ delicate fluoresc...

'Lucky 13' as new gene discovery offers further hope for childhood blindness

...e conditions. This new result is another important step in the right direction and Yorkshire Eye Research is very proud to have supported it." The research was also welcomed by Professor John Marshall, Chairman of the Medical Advisory Board at the British Retinitis Pigmentosa Society. "This dramatic...

Now, self-healing materials can mimic human skin, healing again and again

...ous to small cuts in skin,” Sottos said. “The next step is to extend the design to where the network can heal ‘lacerations’ that extend into the material’s substrate.”...

Researchers reveal structure of protein altered in autism

...ies on neuroligins and neurexins represent a major step toward defining the synaptic organization at the molecular level. “Normally, individual neuroligins are encoded to interact with specific neurexin partners. The two partners are members of distinct families of proteins involved in synaptic adhesi...

Genetic factors are linked to fever following smallpox vaccination

...at the findings represent an important preliminary step in understanding the variations in host responses to vaccines, and notes that further studies will need to replicate these findings, and to test other vaccines. Both Drs. Stanley and Crowe mention that the results may have important implications whe...

Could fungal collection hold the key to new life-saving drugs?

Scientists may be one step closer to finding new drugs to fight MRSA, cancers...hip with SIDR will see CABI’s collection taken one step further, with the fungi being exploited for natural products. Although using biotechnology to dev...

New findings challenge established views on human genome

...the sequencing of the genome marked just the first step toward the goal of using such information to diagnose, treat and prevent disease. Having the human genome sequence is similar to having all the pages of an instruction manual needed to make the human body. Researchers still must learn how to read the...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

...ogrammed to dissolve vesicle membranes, a critical step to delivering the cargo. The nanoparticles are referred to as "smart" because they release their cargo at precisely the right moment after entering the cell. "At the same time that the bacteria are breaking up this vesicle membrane, the cargo disl...

Plastic that grows on trees

...renewable plant matter. Scientists took a giant step closer to the biorefinery this week, reporting in ...glucose is converted to fructose.” Zhang’s next step is to tinker with ionic solvents and metal halides combinations to see if he can increase HMF yield ...

Exploring the dark matter of the genome

...e sequence of heterochromatin is clearly a crucial step toward a better understanding of genome functions. Karpen notes that one intensively studied and puzzling problem in chromosome biology will benefit enormously from the new findings: epigenetics -- the inheritance of traits and genetic informati...

University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts

...r grafts for eventual human application. “The next step is to demonstrate the use of the tissue-engineered blood vessel in a larger animal model, such as a pig, which has a coagulation system more similar to that in humans. The advantage of our approach is that the graft could utilize the patient’s own st...

Gene responsible for common hearing loss identified for first time

... Antwerp, Belgium, said that this finding may be a step towards new treatments for otosclerosis, which affects approximately 1 in 250 people. Otosclerosis is a multifactorial disease, caused by an interaction of genetic and environmental factors. The outcome is a progressive hearing loss as the growing b...

Fat fish put obesity on the hook

... The FASEB Journal, “and with this model, we are a step closer to temporarily turning off or diminishing the fat-storing mechanisms that were once crucial to the survival of our species. The zebrafish has become a model animal for the study of many diseases because it has a backbone and because its geneti...

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