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Tag: "stem" at biology news

First Quantum Grant to fund stem cell repair of damage from stroke

...n developmental neurobiology and vascular biology, stem cell biology, genetics, biomedical imaging, tissue engineering, and clinical cellular therapies. Spanning fields of science that include cell and molecular biology, animal models of disease, and hopefully human clinical trials, the "Neuro-Vascular Re...

Detailed 3-D image catches a key regulator of neural stem cell differentiation in action

...ches orchestrates the differentiation of embryonic stem cells into different tissue types. Being able to m...switches would allow scientists to nudge embryonic stem cells into becoming specific cell types, a plus for both basic research and potential therapies. ...

Knockout Mouse Project

...d will insert the altered genes into the embryonic stem cells derived from the mice. UC Davis will use the altered embryonic stem cells to create adult mice with one missing gene, which are referred to as "knockout mice." This NI...

Key gene controlling kidney development found

... of the kidney by keeping a population of "parent" stem cells constantly available to produce the differen...stics specific to its job in the body. The kidney stem cells, called mesenchymal blastemal cells, are the source of cells triggered by chemical signals to ...

Inheritance outside DNA

...nother, and thus is at the heart of the mystery of stem cells. Genomic imprinting is a type of epigene...s to particularly affect the behavior of the adult stem cells that continually regenerate the colon in mice. This probably plays a role in the increased ris...

Muscle and bone from an ink-jet printer

...o-ink" patterns that directed adult muscle-derived stem cells from mice to differentiate into both muscle ...multiple tissues from a single population of adult stem cells. Bioengineers from Carnegie Mellon University’s Robotics Institute and the Institute for C...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...olecular signature of these epidermal neural crest stem cells in the mouse, their research resolves confl...inctly different from other types of skin-resident stem cells/progenitors. Their work provides a valuable resource for future mouse neural crest stem cell r...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...nt and replacement therapies to include the use of stem cells, soluble molecules, genetic engineering, tis...ye institute in India (L.V. Prasad) has used adult stem cell therapy to repair the corneas of over 125 blind patients; an estimated 60% of blindness in poor...

Embryonic stem cells do better on bumpy nanoscale mattress

...he princess kept awake by the pea, human embryonic stem (HES) cells do better when cultured on a substrate...y’s Department of Chemical Engineering. Unlike stem cells derived from adult tissues, which have a limited number of cell doublings, embryonic stem cell...

Chemical tests of cell growth enter third dimension

... used it on colon cancer cells and mouse embryonic stem cells. And in both cases, we found a very good relation between cell growth and fluorescence intensity." The device can be used with standard well plates, though nine wells are required for each test instead of one. He and his team are expanding the...

Human stem cells delay start of Lou Gehrig's disease in rats

... Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate ...he disease and slightly prolongs life. The grafted stem cells develop into nerve cells that make substantial connections with existing nerves and do not the...

'Tribbles' protein implicated in common and aggressive form of leukemia

...verwhelming effect when expressed in hematopoietic stem cells, the cell type that gives rise to all elemen...ed to express Tribbles-2 (Trib-2) in hematopoietic stem cells developed AML. They also found that Trib-2 inhibited C/EBPá, another protein that is frequentl...

Researchers create genetically matched embryonic stem cells for transplantation

...gy, using eggs alone, for creating mouse embryonic stem cells that can be transplanted without the risk of...ertilized eggs as a source of customized embryonic stem cells that are genetically matched to the egg donor at the genes that control recognition of cells b...

Flu shot effective against drifted influenza, nasal spray vaccine less so

... vaccine effectiveness against drifted viruses may stem from study design. Many vaccine evaluation studies rely on a clinical diagnosis of "influenza-like illness," or measures of the immune response to infection in the blood. For the present study, Monto and lead author Suzanne Ohmit, assistant research...

Neural stem cells lend the brain a surprising capacity for self-repair

The brain contains stem cells with a surprising capacity for repair, resea...ithin weeks. They attributed that repair to neural stem cell "escapees" that had somehow retained or restored the genes' activity and, with it, their regene...

Advance helps explain stem cell behavior

...DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ...esearch is an important step towards understanding stem cell behavior, how cellular development is controlled, and how a single cell ?which has the genetic ...

Stem cell activity deciphered in the aging brain

...tes current ideas on how long crucial "progenitor" stem cells persist in the aging brain. The finding als...ain drain was due to a decreasing supply of neural stem cells in the aging hippocampus, said lead study investigator Bharathi Hattiangady, Ph.D., research a...

Getting to the heart of the heart

...ildren's Hospital Boston have identified a type of stem cell that is the precursor to at least two main ce...'s first author, first worked with mouse embryonic stem cells in culture. They allowed the cells to differentiate in a Petri dish, then isolated a relative...

New target for cancer therapy identified

...odest quantities in most cells. It is plentiful in stem cells where it keeps the telomeres long, allowing the cells to keep dividing without limit which is necessary for the repair of damaged and worn out tissues throughout the human body. However, studies have shown that telomerase also plays a key rol...

Cancer stem cells linked to radiation resistance

Certain types of brain cancer cells, called cancer stem cells, help brain tumors to buffer themselves agai...mage checkpoint response" appears to enable cancer stem cells to survive exposure to radiation and to switch on a signal to automatically repair any damage ...

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