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Tag: "stem" at biology news

Linheng Li Lab documents the development of cancer stem cells

...ly, on a new publication that clarifies how normal stem cells become cancer stem cells and how cancer stem cells can cause the formation of tumors. The paper, "PTEN-deficient inte...

How stem cells are regulated

...ew group of proteins that regulate the function of stem cells. The results are published in the new issue ...e from the same type of primal cell; the embryonic stem cell. Stem cells can develop into any type of cell through a carefully regulated process referred to...

Engineering the heart piece by piece

...own to be changeable into cardiac cells. Embryonic stem cells, while promising, come with political baggage. And other types of muscle cells taken from elsewhere in the body ?including skeletal muscles ?have been used in early clinical trials, but results are mixed. ...

Nanoparticles can track cells deep within living organisms

...body. The researchers believe nanoparticle-labeled stem cells like these could prove useful for monitoring...esearchers believe that nanoparticle-labeled adult stem cells could be used to evaluate tumors. Under an MRI scan, the presence of the labeled cells would r...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...ack patients who received an new intravenous adult stem cell therapy, Provacel? experienced a lower number...%, p=0.027). Provacel is a preparation of adult stem cells pre-formulated for intravenous delivery by the drug's manufacture, Osiris Therapeutics. Patie...

Many couples choose to donate surplus embryos for stem cell research

... chose to donate their surplus, stored embryos for stem cell research, according to a report by the Spanis...he interest level among couples in Spain—where the stem cell research environment is fairly open and people have traditionally been supportive of organ and ...

Cancer scientists create 'human' leukemia process to map how disease begins, progresses

...rt normal human blood cells into "human" leukemia stem cells. The converted cells, when transplanted into...roduced a specific leukemia gene into normal human stem cells and injected the genetically altered cells into mice that lacked immune systems. The result? 1...

Minuscule molecules pack a powerful punch

... called Bic/microRNA-155 (or miR-155) in embryonic stem cells which they used to transfer the mutation into mice. Previous research showed that miR-155 was active in cells of the immune system and overactivity was found in lymphoma development. "Very little is known about the function of the hundreds o...

Stem cell therapy shows promise for rescuing deteriorating vision

..., neural progenitor cells derived from human fetal stem cells have been shown to protect the vision of ani...ity. The neural progenitor cells, which arise from stem cells and further differentiate into different types of cells found in the central nervous system, w...

Reversing cancer cells to normal cells

...cific proteins similar to those found in embryonic stem cells. This groundbreaking work led to the first ...o explain how, by becoming more like unspecialized stem cells, the aggressive melanoma cell gained enhanced abilities to migrate, invade and metastasize whi...

When smell cells fail they call in stem cell reserves

...ins researchers have identified a backup supply of stem cells that can repair the most severe damage to th...hen neighboring cells die, the scientists say, the stem cells jump into action. A report on the discovery will appear online next week in Nature Neuroscienc...

Linking DNA and histone methylation

...ion, two phenomena that play a significant role in stem cell differentiation and cancer, can communicate with each other to turn genes off. " Although both histone and DNA methylation have long been recognized as hallmarks of euchromatic gene silencing, how these two processes cooperate to induce sile...

MIT bioengineer advances survival, promise of adult stem cells

...ique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells. Adult stem cells, found in many tissues in the body, are precursor cells for specific cell types. For example, ...

Research project tackles 'regeneration' gap

... will connect scientists who work with adult human stem cells ?the building blocks of self-renewal that ex... to treat blindness by influencing the activity of stem cells in the human eye. In terms of brain diseases, scientists may look at ways to mobilize and rein...

On automatic pilot

...es, signals from a specific structure in the brain stem are transmitted to Purkinje cells located in the cerebellar cortex. Mossy fibres transmit signals from various parts of the central nervous system to the granule cells of the cerebellar cortex. Pijpers reconstructed the modular anatomy of the cer...

U of MN researchers turn cord blood into lung cells

...e, for the first time, coaxed umbilical cord blood stem cells to differentiate into a type of lung cell. ...ell TM (MLPC TM ) from umbilical cord blood. This stem cell, which was first isolated and characterized by BioE®, Inc., St. Paul, is a precursor cell that ...

Gene key to taste bud development identified

...opment of taste buds. The gene, SOX2, stimulates stem cells on the surface of the embryonic tongue and i... enough SOX2 present, or if there is too much, the stem cells will not turn into taste buds." The researchers made their discovery in mice, but they belie...

Cloned mice created from fully differentiated cells, a milestone in cloning research

New research dismisses the notion that adult stem cells are necessary for successful animal cloning,...derived from fully differentiated cells, not adult stem cells, as most have argued in the nine years since Dolly was first created. Because stem cells have ...

Key to zebrafish heart regeneration uncovered

...s removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue, Duke University Medical Center scientists have found. The scientists further discovered that key growth factors ...

Growth factor stimulates rapid extension of key motor neurons in brain

...replacement of neurons using precursors or 'neural stem cells'," says Macklis, who is on the faculty at Harvard Medical School. ...

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