New test to detect rare proteins in blood
...erformed in an automated format," notes Greene. He states that the technology will soon be robotized so as to be able to screen for many rare disease-causing proteins using tiny amounts of blood. "It is even possible that one could screen for multiple diseases at the same time and produce a precise accounti...Manipulating single cell receptor alters animal behavior
...tracellular events in the regulation of behavioral states and provides new information about the means throu...ractions.Daniels says the regulation of behavioral states by angiotensin "is a well-studied problem that has provided a wealth of information about the interf...Sweet 'water taste' paradoxically predicts sweet taste inhibitors
...an be used both by food industry and in medicine," states senior author Paul A.S. Breslin, PhD, a Monell geneticist. Lead author Veronica Galindo-Cuspinera, PhD, noted while working on a separate study that saccharin ?commonly used at low concentrations as an artificial sweetener ?loses its initially sweet...Ocean virus identified in human blood samples
...cent of the dairy and beef cattle in eight western states had antibodies to Vesivirus, with antibody prevalence in various herds ranging from zero to 80 percent. It concluded that Vesivirus infection in cattle is widespread, and in various studies has been "associated" ?identified to be statistically releva...Invasive species harms native hardwoods by killing soil fungus
...S. in the 1860s, has since spread to Canada and 30 states in the East and Midwest, with recent sightings as far west as Oregon. While many mechanisms -- from the absence of natural predators or parasites to the disruption of long-established interactions among native organisms -- have been proposed to expl...Screening blood for West Nile virus
...recent mandate to screen blood donations in all US states for West Nile virus (WNV) makes little sense from ... to best screen blood samples has been left to the states and the blood collection agencies. Caroline Korves (of Columbia University) in collaboration with ...Pitt professor's theory of evolution gets boost from cell research
...wartz and Maresca explain: Cells in their ordinary states have suites of molecules-- various kinds of proteins--whose jobs are to eliminate error that might get introduced and derail the functioning of their cell. For instance, some proteins work to keep the cell membrane intact. Other proteins act as chape...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...n and why, once infected, they develop more severe states of the disease than whites. The team includes researchers from University of California, Los Angeles (UCLA), and Harvard School of Public Health (HSPH). The paper will appear online in the February 23 issue of Science Express. Approximately eight mi...Environmental tobacco smoke linked to behavior problems in children and pre-teens
...sco. "This study provides further incentive for states to set public health standards to protect children from exposure to environmental tobacco smoke," says Dr. Yolton. Dr. Yolton examined 225 children and pre-teens exposed to at least five cigarettes a day. On average, the children were exposed to a...Stem cells from muscles can repair cartilage
... using enriched stem cells from muscle. The author states that the results are encouraging, especially the successful use of fibrin glue to fill in the defect, and that the study "provides proof-of-principle for performing MDSC implantation in cartilage of adult humans, since 12-week-old rats are considered...ASU researchers 'wire' DNA to identify mutations
..., or bias is used to probe the internal electronic states of DNA. By measuring the conductance, the team was able to understand the sequence information in the DNA and whether there was a mismatch in comparison to a normal DNA sequence. What they found was that just a single base pair mutation in a DNA mo...New technique helps researchers determine amino-acid charge
... on theoretical estimations to predict protonation states -- whether an amino acid is charged or not. Appropriate experimental benchmarks also had been lacking. All cells have membrane proteins that form channels to allow water and/or ions to pass through. Malfunctions have been linked to such problems as ...How E. coli bacterium generates simplicity from complexity
... reports that only a handful of dominant metabolic states are found in E. coli when it is "grown" in 15,580 different environments in computer simulations. "When it comes to genomes, a great deal of complexity boils down to just a few simple themes," said Bernhard Palsson, a professor of bioengineering at ......xplains the chronic character of these infections, states the author of the PhD. The aim of the PhD was the characterisation of the process of formation of the Staphylococcus aureus biofilm. Regulating mechanisms unknown to date The starting point for the research was the Bap protein (Biofilm associ...Image of myosin-actin interaction revealed in cover story of Molecular Cell
...re able to structurally visualize the weak binding states of actin and myosin, not interpolated from crystal structures, and not interpolated from biophysical methods," said Dr. Hanein. "We were able to see structural changes in the myosin lever arm as well as in the actin interface as it propagates through...Health of coral reefs detected from orbit
...tangible environmental effects of global warming," states Dr. Arnold Dekker of Australia's Commonwealth Scientific and Industrial Research Organisation's (CSIRO) Wealth from Oceans Flagship program."The concern is that coral reefs might pass a critical bleaching threshold beyond which they are unable to reg......cal model, which distinguishes the different bound states of the cargo particle and describes the transitions between these states. Using this model, the Max Planck scientists have been able to calculate several transport properties, such as the average velocity and the average walking distance of the cargo...Zooming in on the protein-conducting channel
...e-dimensional maps of the complex in two different states from the low-contrast, noisy images produced by the electron microscope. “What we have achieved is a huge jump in resolution of this complex,?said Frank. “Even so, this resolution would not allow us to study the complex in atomic detail, or even see...Scientists map one of biology's critical light-sensing structures
...ties that enable them to switch between two stable states that sense red and far-red light. The light is actually detected by a specialized pigment that sits within a pocket on the protein. Red and far-red light, says Forest, have the effect of reversibly changing the structure of the pigment in the pocket,...Penn study finds direct role for glial cells in brain cross-talk
...ively communicating with and instructing neurons," states senior author Philip G. Haydon, PhD, Professor of Neuroscience. "Astrocytes are not just the 'kitchen cells' of the brain, providing nutritional support, but instead also help the neurons talk to each other." Haydon and colleagues published their re...