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Tag: "starting" at biology news

Computational verification of protein-protein interactions by orthologous co-expression

...h levels of a chemical called pyruvate, which is a starting material for making glucose, and then accumulated high levels of sirtuin1 protein. (Rodgers will receive the Nupur Dinesh Thekdi Research Award on April 14 for this work as part of the School of Medicine's 28th annual Young Investigators' Day celebra...

Eliminate Data Analysis Bottlenecks in Drug Discovery

...h levels of a chemical called pyruvate, which is a starting material for making glucose, and then accumulated high levels of sirtuin1 protein. (Rodgers will receive the Nupur Dinesh Thekdi Research Award on April 14 for this work as part of the School of Medicine's 28th annual Young Investigators' Day celebra...

DOE JGI launches IMG public online microbial genome data clearinghouse

...program, which targets the use of DNA sequences as starting points for systematically tackling questions about the essential processes of living systems. Andersen is exploring the potential of a particular microbe, Caulobacter crescentus, for heavy-metal remediation in wastewater. "I have found the IMG syste...

Ebola virus: from wildlife to dogs

...ations are under way to identify the stages which, starting from this reservoir, lead to the emergence of human epidemics. Knowledge of the reservoir animal and of the virus's natural cycle should assist in devising suitable prevention strategies against Ebola epidemics. ### Marie Guillaume - DIC (1) This ...

$5.1 billion would save 6 million children

...ryce and their colleagues, published by The Lancet starting in June 2003, which examines the means to reduce global child mortality. They found that at least 6 million child deaths worldwide could be prevented with existing interventions to prevent and treat pneumonia, diarrhea, malaria, neonatal sepsis, pret...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

...s that drive the disease. Our work provides a good starting point for scientists looking for others." As part of the study, investigators did microarray analyses on the two major subtypes of NSCLC, adenocarcinoma and squamous cell carcinoma, and found that their genomic profiles overlap in every area but one...

Newest HIV drugs should be used with FUZEON(R)

... future, which I didn't even consider doing before starting this regimen. I have much more energy now than I h... injection, and more patients are now successfully starting and remaining on treatment. Roche continues to roll out educational initiatives to support patients ...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

...cid mine drainage microbial colony is an excellent starting point because it is a real-life natural world community with a limited number of members. Thus, we can measure and learn about microbial interactions and function distribution in a natural setting without being overwhelmed by an extremely large numbe...

First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology

...e. The egg is sterile and stable, providing a good starting material for isolation and purification of the protein of interest. Moreover, conditions for good manufacturing practices have been long-established for vaccine production in chicken eggs." "This work really exemplifies the spirit of our Small Busin...

Scripps research scientists solve structure of a critical innate immune system protein

...ch responds with a multi-stage biochemical defense starting with the unleashing of an army of white blood cells, like macrophages, which engulf and destroy pathogens. The macrophages also fight the pathogens by producing large amounts of chemicals that induce inflammation and help the body clear the infection...

Major advance made on DNA structure

...tructure." "Now, for the first time, we're really starting to see what the genome looks like in three dimensional reality, not just what the sequence of genes is," Ho said. "DNA is much more than just a string of letters, it's an actual structure that we have to explore if we ever hope to understand biologic...

Researchers track down cause of a disfiguring bone disorder

... as sclerosteosis and Van Buchem disease provide a starting point for understanding the modulation of anabolic bone formation," noted team members Michaela Kneissel and Hansjoerg Keller of Novartis, "and ultimately have the potential to identify key molecular components that can be used as new therapeutic age...

Missing Receptor Molecule Causes Tumor Growth

... of certain tumors in the ovaries. Not because the starting signal is missing, but because this signal cannot be received by the cell. This finding, published today in the American science journal Molecular Cancer Research, shows that these cells lack a receptor molecule called DR4. DR4 is responsible for re...

Bacteria are key to 'green' plastics, drugs

...bacteria make it naturally, so we have a metabolic starting place for large-scale fermentation." The centerpiece of Rice's succinate technology is a mutant form of E. coli that makes succinate as it's only metabolic byproduct. The bug contains more than a half-dozen genetic modifications. It was created over...

Nanoparticles carry cancer-killing drugs into tumor cells

... of certain tumors in the ovaries. Not because the starting signal is missing, but because this signal cannot be received by the cell. This finding, published today in the American science journal Molecular Cancer Research, shows that these cells lack a receptor molecule called DR4. DR4 is responsible for re...

Gap-climbing fruit flies reveal components of goal-driven behaviors

...h the hind and middle legs still holding on to the starting side and the front legs just about reaching the edge of the target side. Forward shifting of the body into the gap, primarily by little hind-leg steps, contributes the most to gap-crossing. Auxiliary actions of the middle legs keep the body close to ...

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

...sible origin for these normal cells and provides a starting point for understanding the basis of medulloblasto...ls reside in the cerebellum and provides us with a starting point for identifying the cells and genes involved in many medulloblastomas." The researchers hypot...

Molecular miners find pain relief drugs from the sea

...cterise ACV1. It was a true collaborative venture starting with genes discovered by Associate Professor Gayle...fessor Gayler says the team, by using genes as the starting point, are able to minimize the number of cone snails required to develop new tools and therapies fo...

Researchers create functioning artificial proteins using nature's rules

...of structure and function that is exhibited by the starting set of natural proteins," Dr. Ranganathan said. "The real test will be to put them back into a living organism such as yeast or fruit flies and see how they compete with natural proteins in an evolutionary sense." Other UT Southwestern researchers i...

Breakthrough in micro-device fabrication combines biology and synthetic chemistry

...es can be chemically modified without changing the starting shapes or fine features, we have opened the door for new research and development in the processing and application of many devices that would otherwise be very difficult or expensive to produce." ...

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