Genomics-based vaccine could prevent deadly cattle disease
... signal," a telltale peptide sequence found at the start of secreted proteins. Sure enough, the scientists found some 400 T. parva genes containing the secretion signal. This set of genes provided a starting pool of candidate proteins. Based on further tests, the study's research team, led by the Interna......ltural institutes in South America and the Asia to start to work out how their knowledge of the defence mechanisms in model plants such as Arabidopsis could be used to improve the photosynthesis rates of staple crops such as rice and the common bean. Professor Julia Goodfellow, BBSRC Chief Executive, co...Scientists discover a genetic switch that links animal growth and cancer
... When the brakes fail, cells that should be static start growing and dividing, leading to cancer. These bra...thout growing. When they eventually find food they start growing and maturing into adults. The researchers discovered that this juvenile-to-adult switch is c...Supersized 'island' of resistance genes discovered in an infectious bacterium
...cted patients die. "Less than 2 years after the start of the French epidemic episode, we found the complete genome ID of the microbe involved and developed a better understanding of what to expect for the future, in terms of new antibiotic resistance," Claverie said. "This work will guide a future inte...UCLA scientists uncover mechanism of response to targeted therapy
...ientists seeking a target for a new cancer therapy start work in cell lines andthen advance to laboratory animals to test their theories. Working backward from responsesin clinical trials is unusual, Thomas said. Responses observed in clinical studies led researchers back to the laboratory. Their laborator...Two NIH initiatives launch intensive efforts to find roots of common diseases
...s initiative will get off to a quick and efficient start that will genuinely produce important advances for...Sciences, Inc., of Mountain View, Calif., and will start in late summer 2006; Pfizer is contributing these Perlegen-produced genotypes as an "in kind" donati...St. Jude projects 90 percent cure rate for ALL
...sign the most effective treatments possible at the start of therapy. That's a key element of our success in raising the cure rate for ALL while limiting toxic effects of therapy." That success is based to a large extent on the work done at St. Jude and elsewhere in identifying specific mutations in leukem...First demonstration of 'teaching' in non-human animals
...e criteria and thus qualifies as teaching. At the start of a tandem run, the leader finds a naïve individual who is willing to follow her. But tandem runs are rather slow because the follower frequently pauses to look round for landmarks so that it can learn the route. Only when the follower has done this...Zebra finches remember songs dad sang
...at allows kids to learn any human language if they start early enough," Vicario says. "These findings are exciting," Kuhl says of the research reported in the paper. "They provide neurobiological evidence that helps explain human infants' acquisition of speech." Vicario, Phan and Pytte worked with zebra......itoring is needed to check whether other serotypes start to cause some disease. It is known that pneumococc... to a form not recognised by the vaccine, it might start to become more prevalent and cause disease. The catalogue of capsules from all known strains will ...New study shows benefit of early therapy in HIV-infected infants
...s, now available online. Uncertainty over when to start antiretroviral treatment in children infected with...begun within months of birth. Policies on when to start ART vary across Europe. Up to this point, the effect of age on clinical outcome has been difficult t...'Dead zone' summer killed billions of ocean state mussels
...ater quality and sea life in the bay. Hypoxia can start when fertilizer or sewage spills into coastal waters, carrying nitrogen, phosphorus and other nutrients. Often fueled by warm temperatures and a lack of circulation, this nutrient rush can cause algae blooms. When the algae dies, it sinks to the bott...Enzyme crystal structure reveals 'unexpected' genome repair functions
...tivate XPB within the TFIIH complex to allow it to start the DNA unwinding process. "Even though TFIIH does not act directly in initial damage recognition, the interaction of XPB with the DNA lesion suggests that XPB plays a role in switching TFIIH from transcription mode to NER," Tainer says. "The struc...Genes affecting blood pressure change as children become adults
...the other continues taking a bus or even that they start going to different schools.Environmental factors a... tending to have higher rates of hypertension that start at a younger age, he says. ...Convergent evolution of molecules in electric fish
...onally important," he says. "Natural selection can start showing you the important parts of molecules. We took the evolutionary approach, which is very compatible with the clinical approach." ...Suicide risk does not increase when adults start using antidepressants, study finds
...de generally decreases in the weeks after patients start taking antidepressant medication, according to a n...rcher on the study. "The period right after people start taking antidepressant medication is not a period of increased risk. In fact, risk after starting med...Alaska seal pup diet may hold key to decline of population
...iet, Polasek said. A seal that weighed 26kg at the start of the study, on the high-fat diet, has also continued to grow in a similar manner. These results fit with a recent study by a team from Göteborg University that found wild seal pups smaller than 26 kg when they were weaned were less likely to survi...COX-2 inhibitors significantly reduce risk of cancer
...fects, so we are not advising people to go out and start taking them until more studies confirm that they are safe and effective," says Harris. Celebrex is still widely used for pain relief, but Vioxx was pulled off the market in 2004 following reports of heightened risk of heart attacks. "It's clear tha...Trial success for diabetic nerve therapy
...s novel therapeutic when phase-two clinical trials start later this year." The incidence of diabetes, a condition in which the amount of glucose in the blood is too high, is increasing dramatically with the World Health Organisation estimating that some 300 million people worldwide could be affected by 20...Scientists find Antarctic ozone hole to recover later than expected
...nificantly shrink, something they predict will not start to occur until 2018. Newman's team also further indicated that greenhouse gas-forced climate change will have only a small impact on the Antarctic stratosphere and recovery of the ozone hole. The upper ozone layer is important because it blocks 90-9...