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Tag: "stages" at biology news

Single microRNA causes cancer in transgenic mouse

...in the bone marrow and then evolve through several stages before they become mature enough to create antibodies. Antibodies are proteins that sit on the surface of B cells or that are secreted by B cells that can detect the presence of foreign invaders like bacteria, viruses or parasites. Lab tests reveal...

Front-line immune cells mature in four stages, study shows

Researchers here have cracked the site and the stages of development for the last major set of human imm...d bone marrow, respectively. However, the site and stages of human NK cell development have eluded investigators until now. The findings advance the underst...

Novel molecular 'signature' marks DNA of embryonic stem cells

...nd probably coordinate their activity in the early stages of cell differentiation. Not only do these findings help to unlock the basis for ES cells' seemingly unlimited potential, they also suggest ways to understand why ordinary cells are so limited in their abilities to repair or replace damaged cells. "...

In the mind's eye: How the brain makes a whole out of parts

...," Connor said. "It happens at multiple processing stages in the brain. We study how objects are signaled or...ed by large populations of neurons at higher-level stages in the object-processing part of the brain." The report, based on recordings of nerve cells in the ...

Potential vaccine developed for deadly leishmaniasis disease

...al leishmaniasis candidate vaccines are in various stages of development. Seeberger’s group, however, reported development of a unique two-part preparation. It is among a new genre of carbohydrate-based vaccines stirring excitement in medical circles. Carbohydrates are chemical compounds that include sugar ...

Nanotechnology may find disease before it starts

...y one day help physicians detect the very earliest stages of serious diseases like cancer, a new study suggests. It would do so by improving the quality of images produced by one of the most common diagnostic tools used in doctors' offices ?the ultrasound machine. In laboratory experiments on mice, scient...

The closest look ever at the cell's machines

...smantle and reassemble their machines at different stages of the cell cycle and in response to environmental challenges, such as infections. "This would be a logistical nightmare if the cell had to build every machine from scratch any time it needed to do something," says Anne-Claude Gavin, former Directo...

Driver of anthrax toxicity could lead to late-stage therapy

...tential to protect against anthrax during the late stages of the disease, after antibiotics have lost their ...t the effects of accumulated toxin during the late stages of anthrax disease when antibacterial methods normally are no longer of therapeutic value," the rese...

Low-cost drug gaining favor for use in HIV-infected children in poor countries

...d" for children in all age groups and in different stages of HIV illness, Grimwade said. Every medication has side effects, and the trial did uncover some adverse reactions from cotrimoxazole. Still, Grimwade said the Zambian study shows that the drug is a safe precaution against opportunistic infections i...

Gene needed for butterfly transformation also key for insects like grasshoppers

...subtle physical changes during each of its nymphal stages as it progresses to adulthood. If broad is suppressed, the nymph simply repeats the appearance from its previous phase but continues to show normal growth, Erezyilmaz said. The organism eventually becomes an adult, but adult structures such as the wi...

UC Berkeley researchers create a biologically-inspired artificial compound eye

...t basing a fabrication system on the developmental stages of insect eyes that I'd learned about as a biophysicist and bioengineer." What he and his team came up with is a low-cost, easy-to-replicate method of creating pinhead-sized polymer resin domes spiked with thousands of light-guiding channels, each ...

Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus

...lls, the nature of neurological changes in earlier stages of the disease, the so-called "chronic phase," were unknown-until now. Using simian immunodeficiency virus-infected models in the chronic phase, the research team found both virus and infiltrating lymphocytes (CD8+ T cells) in the brain. Molecular a...

Immune response to HIV in the brain

...lls, the nature of neurological changes in earlier stages of the disease, the so-called "chronic phase," were unknown-until now. Using simian immunodeficiency virus-infected models in the chronic phase, the research team found both virus and infiltrating lymphocytes (CD8+ T cells) in the brain. Molecular a...

Minimal genome should be twice the size, study shows

...tially use it to predict gene content at different stages of an organism's evolution. "This will help us understand more about how the genome of different organisms have evolved over long periods of time and should also inform attempts by experimentalists to construct minimal genomes by gradual evolution ...

Pain killer fights breast cancer by targeting key enzyme

...ggemeier said. "We are obviously in the very early stages of drug discovery with nimesulide analogs, and a long path of preclinical research is needed before we can even begin to think about potential drugs." The researchers took several of these nimesulide analogs and, in laboratory cultures, tested their...

Liver cancer linked to cellular repair pathway

...vity in cirrhotic patients could alert us to early stages of liver cancer, as well as provide valuable prognostic information for patients," he said. Sicklick and colleagues also discovered a new Hedgehog pathway mutation in a patient with liver cancer that may lead to overactivation of Hedgehog and trigge...

Clawed frog helps Fanconi anemia research make leaps

... is that cultured human cells are at all different stages of the cell cycle. The bulk of the cells are not r...me, or synchronously, allowing naturally regulated stages of division to be studied simultaneously. "It's very hard to synchronize mammalian cells," Hoatlin...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

... they infiltrate a transplanted heart in the early stages of organ rejection. This pre-clinical advance, des...ow a transplanted heart changes through sequential stages of rejection while the rat stays healthy. This aspect of the research was conducted primarily by Qin...

Picking particles faster than one at a time

...much attention on the particle itself in the early stages of picking -- for example, approximating its shape and creating a template into which real images are forced to fit, a process common to all previous automatic methods -- simply added to the difficulty. "We decided that if there's noise, there's nois...

The secret love life of plants

...sk of nourishing the plant embryo during the early stages of its development. In flowering plants, there is a complicated double-fertilisation mechanism that arises among embryos and endosperm. They develop together into mature seeds. The exact process, and the communication between the two parts of the s...

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