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Tag: "stage" at biology news

Clues to breast cancer hidden inside stem cells

...breast becomes fully differentiated, and once this stage is over, it involutes. This cycle of proliferation, differentiation and apoptosis also happens in every menstrual cycle and in a more dramatic form during pregnancy. "This caught our attention, and has driven our research," Sigurdsson pointed out. B...

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

...uld also be the first compound to treat the latent stage of infection as well. Researchers report their results today at the 2006 ASM Biodefense Research Meeting. "The class of which this compound is the lead has a very different mechanism of action from any other drug currently used to treat tuberculos...

Defective immune system response to smallpox vaccine detailed in new study

... the immune response of people with eczema set the stage for eczema vaccinatum. When exposed to vaccinia virus, the skin samples from healthy volunteers and from those with psoriasis reacted by producing more LL-37. As a result, the replication of the virus was controlled and eventually halted. In contrast...

Born with a love of speech

...ral student at the time of research. In the first stage of the experiments, Dr. Vouloumanos and her colleagues compared the response of 10 to 72-hour-old infants to the speech-like sounds and those of monosyllabic nonsense words, such as "lif". When the neonate sucked on a sterilized pacifier, one or the ...

Potential vaccine developed for deadly leishmaniasis disease

...against anthrax and tuberculosis are at an earlier stage of development. One major drawback with carbohydrate vaccines is the difficulty in getting them to produce a strong immune response. Vaccine manufacturers achieve this by adding a booster substance ?an adjuvant. The standard existing adjuvant, alum,...

Stem cell study for patients with heart attack damage seeks to regenerate heart muscle

...us, embryo or animal. Because they are in an early stage of development, it is believed that they do not trigger an immune response when placed in someone else's body. Similar to Blood Type O, these MSCs are being used without tissue type matching to a specific patient. Dr. Schaer says the cells are grow...

Front-line immune cells mature in four stages, study shows

...rk." The researchers also isolated cells of each stage and showed that under the proper conditions, stage-1 progenitor cells matured into stage-2 NK cells, and that these cells matured into stage-3 cells and stage-4 cells, with the hallmarks and cell-killing capacity of mature NK cells. The researchers...

Cloned stem cells prove identical to fertilized stem cells

...ized. The egg develops into a blastocyst, an early stage embryo consisting of no more than 100 or so cells. The scientist can then either remove the stem cells from this blastocyst, or place it into a uterus where it has the potential to develop into a fetus. Here's where things get complicated. The origi...

Wound monitor 'sniffs out' infections

...make it difficult to detect infections at an early stage and can be extremely invasive causing the patient a great deal of discomfort". "Our aim is to produce a non-invasive system that can monitor the state of a patient's wounds simply by detecting bad bacteria in the air emitted from the wound. Using st...

Two NIH initiatives launch intensive efforts to find roots of common diseases

... of patients and controls) is needed for the first stage of genotyping. Follow-up studies to validate the results with additional patients and controls, data analysis, and patient management expenses will add to these basic costs. It is important to note, however, that these costs are a small fraction of w...

Worm hormone discovery may aid fight against parasitic disease

...maturity. Instead, the worms went into a "resting" stage called the dauer diapause, in which they don't eat...t against human disease because the dauer diapause stage of C. elegans is very similar to the infective state of parasitic nematodes. According to the World ...

For the first time: Longevity modulated without disrupting life-sustaining function

... development and enter a dormant, hibernation-like stage in which they can hang on for months but don't reproduce. Unless Smk-1 is missing, that is. Without Smk-1 to provide guiding assistance, DAF-16 is unable to slow down the aging process, and the worms die young. "These mutants are shorter lived bec...

Can dogs smell cancer?

...ty can distinguish people with both early and late stage lung and breast cancers from healthy controls. The research, which was performed in California, was recently documented by the BBC in the United Kingdom, and is soon to be aired in the United States. Other scientific studies have documented the abi...

Vital ocean prey play active role in environment

...he course of several weeks. The larvae are at this stage dependent on microorganisms found on the underside of sea ice for food, and as they grow they drift with pack ice. After they metamorphose in late winter and early spring, the juveniles move with the currents back to inshore waters. In summer, the ju...

Newly discovered killer cell fights cancer

...o be a newly identified actor on the immune system stage that retains all the molecular characteristics of ...f fluorescent-tagged IKDCs and their corresponding stage of transformation after infecting mice with bacteria called listeria. In assassin-mode, the IKDCs w...

Proteins stop blood-vessel and tumor growth in mice

...s process, known as metastasis, is the most lethal stage of cancer and the leading cause of cancer-related death. Fighting cancer by starving tumors of life-giving blood vessels has generated great interest in recent years. In their most recent experiments, Dr. Schiemann and his colleagues injected a biol...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...t death from colorectal cancer, independent of the stage or location of the cancer, or the age or gender of... patients was correctly identified, independent of stage and location," said the lead author, Hans J. Nielsen, M.D, DMSc., Professor of Surgical Oncology, at...

AIDS-related cognitive impairment exists in two separate forms

...t death from colorectal cancer, independent of the stage or location of the cancer, or the age or gender of... patients was correctly identified, independent of stage and location," said the lead author, Hans J. Nielsen, M.D, DMSc., Professor of Surgical Oncology, at...

Even fish don't swim well when they're young!

...ore than 99% of the mortality occurs in the larval stage so anything that might explain what holds them back is useful". Müller will present her research on Monday 3rd April, at the Society for Experimental Biology's Annual Main Meeting in Canterbury [session A5]. The 'burst-and-coast' method of swimming ...

USC researchers investigate protein that protects tumors

...the tumors ?and it's expressed from the very first stage of the cancer formation." The next step was to determine EphB4's purpose. What the scientists discovered was that EphB4 serves as a sentry, guarding the tumor cells from any defenses the body deploys to attack them. "There are means in the body to ...

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