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Tag: "stage" at biology news

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

...es that did not receive hTERT remained in an early stage of benign growth. Finally, the team looked at the PI3K and Raf pathways, frequently implicated in the development of melanoma. They found the expression of active PI3K, together with CDK4, hTERT, and inhibition of p53, produced invasive melanoma gro...

Researchers create infectious hepatitis C virus in a test tube

...ence Express, will allow scientists to study every stage of the HCV life cycle and develop drugs to treat this life-threatening disease that affects more than 170 million people around the world. "The inability to reproduce aspects of the hepatitis C virus life cycle in cell culture has slowed research pr...

Discovery suggests why stem cells run through stop signs

...en light to pass from the normal stop phase to the stage in which they begin replicating their DNA for later division. In their work, Carthew and Ruohola-Baker focused on fruit flies, which have approximately 80 types of microRNAs. They genetically modified stem cells from the fruit flies' ovaries and stu...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

... is reporting that it has detected an intermediate stage between the virus' merger with the cell membrane a...ting drugs can be re-evaluated to pinpoint at what stage they actually work, to fine-tune their activity." The experimental set-up for this study was devise...

Newfound roadblock to interferon effectiveness against malignant melanoma

...tion to the behavior of melanoma cells in the late stage of the disease. The findings explain the frequent failure of interferon therapies and thus further our understanding of melanoma in its late, and most aggressive, stage. In the future, a routine analysis of the STAT5 status in melanoma patients migh...

NHGRI Selects 13 More Organisms for Genome Sequencing

... for their scientific merits. “We want to set the stage for a greater understanding of the major biological innovations that have occurred throughout evolution, with emphasis on learning more about our own genome. Genomic information from a wide array of species already is proving useful in many areas of ...

Possible treatment found for 'chemobrain'

... for their scientific merits. “We want to set the stage for a greater understanding of the major biological innovations that have occurred throughout evolution, with emphasis on learning more about our own genome. Genomic information from a wide array of species already is proving useful in many areas of ...

Pollution-eating bacteria produce electricity

...nerate electricity. A bacterial spore is a dormant stage of growth for the organism and is highly resistant to heat, radiation and drying. Such characteristics could prove useful in future microbial fuel cell designs where the device need not always be operational but must survive long periods of hazardous...

Public release of pig genomic sequences

.... The endeavour will be incorporated into the next stage of the pig genome project in which a draft sequence map of 6 fold genome coverage will be produced. This effort will be coordinated by the international Swine Genome Sequencing Consortium (SGSC) led by scientists from USA and UK. A simultaneous annou...

‘Blue Brain?project explores thought at molecular level

.... The endeavour will be incorporated into the next stage of the pig genome project in which a draft sequence map of 6 fold genome coverage will be produced. This effort will be coordinated by the international Swine Genome Sequencing Consortium (SGSC) led by scientists from USA and UK. A simultaneous annou...

Researchers discover how malaria parasite disperses from red blood cells

...nfects red blood cells. Called a merozoite at the stage of its life when it infects red blood cells, the p...the other stained the parasites red. In the first stage of the merozoites' release, which the researchers dubbed the "irregular schizont" stage, the red blo...

Computers close in on protein structure prediction

...cess happens in two steps, Bradley said. The first stage uses an approximate model which allows rapid calcu...plored in detail in the second stage. The first stage takes advantage of the fact that all amino acids have identical sections, which form the protein bac...

How HIV disables the cells' call for help

...nvelop fuses with the cell membrane in the initial stage of cell infection. The researchers suspected that FP, which is only exposed for a short period during this process, may have enough time to affect the immune response as well. Indeed, they found that FP locks on to several proteins on the cell walls ...

Infectious disease expert warns of spread of Rocky Mountain spotted fever

... where rashes do not usually appear. At this later stage of infection, antibiotic therapy becomes somewhat less effective. In the CDC-led study, government researchers took blood and skin tissue samples from 16 patients across Southeastern Arizona suspected of having the infection. Laboratory tests, inclu...

NYU biologists map out early stages of embryo formation

...rs at Harvard and Yale Universities, which set the stage for these most recent findings. An essential aspect of these studies was the coordination between experts in cell and molecular biology and those with computational and mathematical backgrounds. ...

Scientists find a maturity gene in fly

...principal author. "Without this gene, the juvenile stage is shortened, and it enters adulthood early. The a...tion of a human "from a juvenile, non-reproductive stage to a mature, sexually reproductive adult," says Thummel, a professor of human genetics at the univer...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

...principal author. "Without this gene, the juvenile stage is shortened, and it enters adulthood early. The a...tion of a human "from a juvenile, non-reproductive stage to a mature, sexually reproductive adult," says Thummel, a professor of human genetics at the univer...

Mosquitoes are more attracted to individuals infected with malaria

...a, one infected with the non-transmissible asexual stage of the disease, and one with no infection. A devic...icantly more mosquitoes if they had the infectious stage of the malaria parasite. Moreover, when the children were treated with antimalarial drugs, there was...

Brain networks change according to cognitive task

...n the Journal of Neuroscience effectively sets the stage for further development in our understanding of neuroscience. In their article, the Northwestern scientists provide evidence of the ways in which different cognitive goals are achieved from the interaction between different brain regions. In additio...

Stolen gene allows insect virus to enter cells

...t the f gene stays quiet until the third and final stage of a maggot's development, then begins to produce F proteins, which persist into adulthood. "f seems to be developmentally regulated, like a lot of Drosophila genes," says Blissard. Exactly what role the F protein plays in fruit flies remains to be a...

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