Continued reduction in the number of drug-related deaths in the UK
...rtion of intentional self-poisoning cases remained stable at 35 percent. Opiates/opioids (i.e. heroin/morphine; methadone; other opiate/opioid analgesics), alone or in combination with other drugs, accounted for the majority of fatalities (68 per cent) in 2004. Even though the total number of deaths had ...Human cerebellum and cortex age in very different ways
...gene activity levels in the cerebellum remain more stable as a person ages suggests that this region of the brain experiences less oxidative stress and damage as part of normal aging." "Much remains to be learned about how the brain ages and how changes in gene expression over time are related to brain act...Plants reveal a secret and bring researchers nearer a cleaner future
...ynchrotron light was crucial: "A very intense and stable X-ray beam is necessary to perform this study on such a complex, highly diluted protein present in the investigated spinach sample", explains Pieter Glatzel, head of beamline ID26, where the experiments were carried out. The researchers measured the...Restaurant seafood prices since 1850s help plot marine harvests through history
...nce then the inflation-adjusted price has remained stable or fallen slightly. 3) Inflation-adjusted prices ...een prior to 1909. The large pelagic swordfish had stable inflation-adjusted prices until the mid 1950's, after which they rose rapidly. Prices rose three tim...Embryonic stem cells accrue genetic changes
...yonic stem cells are actually far more genetically stable than other stem cells, but our work shows that even they can accumulate potentially deleterious changes over time," adds Anirban Maitra, M.B.B.S., an assistant professor of pathology at Johns Hopkins who shares first authorship of the paper with Dan ...War on terror meets war on cancer
...Ratio Analysis Combats Terrorism The analysis of stable isotopes ?forms of an element that are stable because they do not decay radioactively ?started out as a way to learn about how ecosystems work, ba...Bacteria which sense the Earth's magnetic field
...t clear how the cells organise magnetosomes into a stable chain, against their physical tendency to collapse by magnetic attraction. But using modern molecular-genetic and imaging processes, researchers from the Max Planck Institue for Marine Microbiology in Bremen and Max Planck Institute of Biochemistry i...Double trouble: Cells with duplicate genomes can trigger tumors
... the centrosome that plays a role in maintaining a stable genome. The extra centrosomes may be at the root of the cancer-triggering process. Once the genetic instability sets in, tumors "evolve " by losing, gaining and rearranging chromosomes. Late-stage tumors commonly have too many centrosomes and a nea...Scientists map one of biology's critical light-sensing structures
... properties that enable them to switch between two stable states that sense red and far-red light. The light is actually detected by a specialized pigment that sits within a pocket on the protein. Red and far-red light, says Forest, have the effect of reversibly changing the structure of the pigment in the ...Bugs expose underground carbon traffic system 10 times more important than fossil fuel burning
... exposed to a particular form of carbon dioxide (a stable isotope of carbon, 13C) for 7 hours, a technique called pulse labelling. Concentration of 13C in cores was then analysed. The soil cores which were exposed to the mites were found to have 32% less 13C than the control cores. This showed that Collemb...Synthetic Protein Eases Arthritis Symptoms in Mice
...TNFR-2. The scientists next aim to develop a more stable form of P60 PLAD. Ultimately, they hope to test the protein in clinical trials. The research was also supported by the National Institute of General Medical Sciences, part of the NIH. ...Discovering the first steps in transcription-coupled repair
...out in vitro, XPG and CSB together formed a large, stable complex with the polymerase. XPG's function during damage removal is to cut the damage-containing DNA strand on one side of the lesion, as part of a complex cut-and patch process. But when the damage causes stalled transcription this site is inside ...Overfishing may drive endangered seabird to rely upon lower quality food
... feathers they sampled were obtained. Measures of stable carbon and nitrogen isotopes ?derived from food ingested at the time the birds create feathers and preserved into the feathers ?give clues to the birds' diet. More nutritious food items, such as sardines, anchovies and squid, are distinguished in the...Research: Snails were overlooked contributors to marsh destruction
...ubsequent waves of habitat die-off in an otherwise stable ecosystem," Silliman said. "For marsh ecology, the message is even clearer: The long-standing paradigm that bottom-up forces rule is officially dead." Climate change aside, the study also falls in line with other recent studies highlighting the rol...Expert dispels bird flu paranoia
...sically on boots or other clothing. The virus is stable in water for up to 200 days and in droppings for four to five days, but can be stopped by heat, sunlight and most detergents. Authorities have confirmed the dangerous H5NI strain of bird flu in South East Asia, Russia and Eastern Europe but not in ...Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer
... the 4th cycle assessment. Twenty-one patients had stable disease (SD). In treatment-refractory patients with advanced breast cancer this preliminary response rate (15%) appears promising. Based on the preliminary results of this study, the predominant serious side effect related to E7389 was neutropenia ...Setting the standard for computer models of life
... who created it, whether it's been modified, and a stable link to its full description; the second scheme links the components of the model to relevant bioinformatics resources: for example, a model of alcohol metabolism in the liver would be annotated with links to the protein databases for all the enzymes...A salty tale: New bacterial genome sequenced from ancient salterns
...llent) amino acids, making them soluble and highly stable at such salt concentrations. Researchers recognized this biochemical adaptation: it's the same one used by archaea also living in the salterns. That wasn't the only similarity. Scientists also found two types of rhodopsin genes: one variety typical ...Bioengineers create stable networks of blood vessels
...pic studies showed that the vascular networks were stable as implants for up to six weeks and were able to c... two important engineering enhancements to develop stable functional microcirculation. First, they created a "micro-scaffold" of a macroporous hydrogel polyme...Whole-genome study at Johns Hopkins reveals a new gene associated with abnormal heart rhythm
...in the absence of a major cardiovascular event, is stable over time, making it a reliable measure." Identifying those at high risk for sudden cardiac death before fatalities occur has been challenging, both at the clinical and at the genetic level, says the study's other first author, Arne Pfeufer, M.D., ...