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Tag: "stabilizing" at biology news

South America's vast pantanal wetland may become next everglades, UNU experts warn

...oviding storm protection and flood mitigation, and stabilizing the local climate, particularly rainfall and temperature. Today, however, these services are compromised by the global problem of climate change while local pollution, habitat destruction and narrowing migration corridors for many species are among ...

Conserved amino acids play both structural and mechanistic roles in sandwich-like protein

...nd that three of the amino acids are important for stabilizing the final structure of the protein, and three serve to direct the process of protein folding. "We directly demonstrated that in one protein within the large sandwich-like protein family, evolution has indeed preserved amino acids for mechanical reas...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...ched in April 2001, and has set a new standard for stabilizing whole blood cellular RNA profiles at the time of blood collection in an evacuated blood collection tube. This enables researchers and clinicians to perform more accurate analysis of gene expression profiles without the variations caused by sample col...

New complete muscle grown in the lab

...ng within the muscle tissue. Thanks in part to the stabilizing influence of the fibroblasts, the surface area covered by vessel cells and the percentage of vessel-like structures in the tissue doubled within two weeks. The endothelial cells and the vessel networks that they provide may also be useful in coaxing...

Brittle prions are more infectious

...eatment strategies for prion diseases might aim at stabilizing prion aggregates. By preventing the aggregates from being broken up to smaller seeds, their propagation can be reduced. In contrast, most such strategies now aim at preventing the proteins from forming in the first place," he said. In future studies...

Researchers image molecular motor structural changes

...used to treat breast and ovarian cancers, works by stabilizing microtubules. But the problem with using Taxol as a general inhibitor of cell division is that it works on all dividing cells, not just those involved in tumors or cancers, and so causes unwanted side effects, such as hair loss. "With this new infor...

Tiny Tampa Bay fish key to evolution of immune system

...g clues as to which atoms are participating in key stabilizing interactions. Doctors often use infusions of antibodies to bolster immune systems weakened by cancer or other conditions, but ironically, these proteins are susceptible to enzymes that break them down. A number of such monoclonal antibody-based dru...

Selective marker found to indicate aggressive form of breast cancer

...function, the protein is thought to have a role in stabilizing the structure of adult stem cells as they regenerate and divide into daughter cells. "Normal basal epithelial tissue produces nestin, but basal epithelial tumors produce a tremendous amount of nestin, which likely represents an abnormal expansio...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...tions that nevertheless exert a number of critical stabilizing forces," said Dr. Snyder, director of Stem Cells and Regeneration at Burnham. "In fact, our study offers the first evidence that stem cells employ multiple mechanisms -- not just cell replacement - which collaborate to benefit disease. These findings...

Scripps research study shows humans and plants share common regulatory pathway

...rly suggests that this protein plays a key role in stabilizing Nod1 and protecting it from degradation. In contrast, turning off SGT1 did not alter levels of Nod1." In an earlier study, Ulevitch’s laboratory reported that Nod1 also interacted with the COP9 complex, a multiprotein complex that is known to pla...

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