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Tag: "spur" at biology news

Gene variations explain drug dose required to control seizures

...out the world, Goldstein said. Both drugs commonly spur adverse reactions. "Physicians have long recognized that patients with the same condition differ in their responses to the same drugs," said neurologist and epilepsy specialist Sanjay Sisodiya, M.D., leader of the University College London effort an...

Hirsute Or Hairless? Two Proteins May Spell The Difference

...criptional and behavioral properties in cells that spur bud formation. In previous experiments, Fuchs and colleagues showed that reducing expression of E-cadherin—a membrane protein that forms the adhesive junctions between epidermal cells—is essential for allowing the cell remodeling required for bud fo...

Leprosy microbes lead scientists to immune discovery

...erving as a trip-wire to raise the alarm. The TLRs spur the monocytes to differentiate into the two rapid response cell types. Why this matters became strikingly clear when the scientists studied different forms of leprosy for the presence of the two cell types. (One of the types, the microbe-eating macr...

Mouse gene shows new mechanism behind cardiac infarction in man

...hronic inflammatory diseases. The new finding will spur further research into the relationship between the protein and cardiac infarction. Hopefully it will offer a new therapeutic technique for the treatment of atherosclerosis and thus reduce the risk of cardiac infarction. ...

NIAID begins clinical trial of West Nile virus vaccine

...e body's immune system--both helper T cells, which spur the production of antibodies to block the WNV from gaining entry into cells, and killer T cells, which kill WNV-infected cells outright. "The DNA vaccine's exploitation of both cellular and antibody immunity offers a potentially potent defense again...

An (ecological) origin of species for tropical reef fish

...ical speciation model for coral reef organisms may spur the development of a more synthetic treatment of speciation on land and sea. Coral reefs, like tropical forests, express an extreme of life's capacity for variation. Yet high biodiversity in tropical seas foil evolutionists' attempts to explain the ...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...on, cell death and the cell proliferation that can spur cancer, the researchers added. Therefore, similar mechanisms might also underlie other disease pathways. Collaborators on the study include Tatyana Sotnikova, Sebastien Marion, Robert Lefkowitz and Raul Gainetdinov, all of Duke. The work was support...

Scientists map one of biology's critical light-sensing structures

... light to guide their development. It will likely spur a rush by scientists to capitalize on the new knowledge and may one day lead to such things as plants whose growth, flowering and death can be precisely manipulated. "We can now start changing how phytochromes work in a rational way to improve how p...

Common viruses may cause cancer

...ions in the number or structure of chromosomes can spur tumor formation is more than a century old. Such aberrations--known collectively as "aneuploidy"--arise in two principal ways: as a consequence of abnormal cell division, or as a result of cell fusion. By either mechanism, the resulting aneuploid cel...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

...rs may be one step closer to finding a safe way to spur production of this missing protein in patients with the most common form of the hereditary bleeding disorder. Using a dormant strand of DNA that has quietly existed in fish for millions of years, the researchers replaced the faulty gene responsible f...

NJIT engineer poised to take stem cell research a step forward

...ents who have cartilage damage. She and Jaffe will spur cartilage regeneration by combing stem cells with bio-degradable scaffolds that mimic fibers found in human cartilage tissue. They will test different scaffolds and determine which biomaterial is the best catalyst for stem cell differentiation. Again...

Scientists re-engineer a well-known antibiotic to counter drug resistance

...r said. "We hope that our pioneering efforts will spur further research into the development of more potent antibiotics." ...

Genetic tug of war determines sexual differentiation

...ecialized cells known as Sertoli cells, which then spur the cascade of events leading to the formation of the future seminiferous tubules of the adult testis," she continued. "Once the testes are formed, they start producing testosterone, which commits the whole animal to male development. The researcher...

HIV-1's high virulence might be an accident of evolution

...the course of viral evolution predisposed HIV-1 to spur the fatal immune system failures that are the hallmarks of AIDS, researchers report in the June 16, 2006 Cell. AIDS has killed more than 25 million people since it was first recognized in 1981, according to The Joint United Nations Programme on HIV ...

What animals can tell us about hemorrhage, organ transplants and aging

...gical principles that may apply to humans, and may spur future medical advances to benefit people. These scientists exude an enthusiasm for their work and maintain a wonderment of the physiological adaptations in the animal world. Science writers can meet and interview many of these scientists at the Co...

Molecular 'on/off switch' controls immune defenses against viruses

...its shape and sends signals to other proteins that spur production of interferon, a molecule that stops vi...d drugs that could mimic viral effects on RIG-I to spur antiviral response or, conversely, mimic viral effects on LGP2 to shut down RIG-I activity. RIG-I sh...

76 percent of workers older than 60 years of age are overweight or obese

...; and in the second place, it is a self-generating spur for acute myocardial infarction, cerebrovascular incidents, and peripheral arteriopathy. Diverse research groups from the department of Cardiology at the University Hospital are working to fight against these illnesses, which have become the prim...

New dwarf buffalo discovered by chance in the Philippines

...om long ago. Finding this new fossil species will spur us to new efforts to document the prehistory of our island nation." The Philippines include more than 7,000 islands. During the last glacial maximum about 20,000 years ago, much of the water in the oceans was frozen in glaciers, resulting in much l...

Scientists win grants to develop $1,000 genome sequencing technology

...ions to other diseases, and cancers. In order to spur the development of fundamentally new and innovative technologies necessary to reduce the cost of sequencing a genome 10,000-fold, the National Human Genome Research Institute (NHGRI) has awarded $13 million in new grants to nine universities and corp...

MIT device draws cells close -- but not too close -- together

...o rearrange cells over time to learn which signals spur change and which don't. In the past, researchers erected chemical "moats" around cells in an attempt to keep them close but separate. Over time, however, cells invariably breech the divide. "They are very good at crossing the moat," said Bhatia, ...

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