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Tag: "spot" at biology news

New U. of Colorado at Boulder flu chip may help combat future epidemics, pandemics

...ntains a specific sequence of "capture" DNA. Each spot is approximately one-hundredth of an inch in diameter. The microarray is then immersed in a wash of influenza gene fragments obtained from the fluid of an infected individual. RNA fragments from the infected fluid bind to specific DNA segments on ...

Discovering the first steps in transcription-coupled repair

...NAPII. The researchers learned that these proteins spot stalled RNAPII whether or not there is damage to DNA -- suggesting that a hitch in the transcription process, not necessarily involving damage to the DNA itself, is the cause of subsequent problems. "It appears that XPG is needed to help CSB recogni...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

...k might lead to nanotube-based biosensors that can spot circulating cancer cells in the blood from a new cancer or from a treated tumor that has returned. Balaji Panchapakesan, Ph.D., at the University of Delaware in Newark, and his co-workers coated the surface of microscopic carbon nanotubes with a m...

Dangerous tricksters: Some bacterie use immune cells to reproduce

...bes, and immune cells are quickly recruited to the spot to neutralise the intruder. Macrophages, cells whose job is to devour such intruders, are attracted by substances typical of bacteria, which surround the microbe like a cloud. As soon as the immune cells have detected the intruder, they cover the bac...

Restaurant seafood prices since 1850s help plot marine harvests through history

...he history of marine animal populations is a blind spot in human knowledge being filled by the combined efforts of historians, paleo-ecologists, and ecosystem modelers. Helping visualize the past, now almost unimaginable richness of the oceans could inspire and influence the way marine resources are manag...

MicroRNAs have shaped the evolution of the majority of mammalian genes

..."conserved," meaning that they show up in the same spot on the same gene across species as disparate as the mouse and the chicken. The authors of last January's Cell paper showed that thousands of human genes contain microRNA sites that are conserved in this way. To the extent that evolution has preserved...

Software 'agents' could help unmask reality of disease clusters

... privacy of patients could be hampering efforts to spot disease clusters and monitor the health effects of environmental pollution, according to researchers in the latest edition of the Journal of Biomedical Informatics . Data made available to research groups investigating everything from cancer cluste...

Emerald Spectre haunts Ontario's ash forests

...lso reported in Ohio and Indiana. The one bright spot in the study is the apparently successful eradication of a borer population that was introduced into Maryland and, subsequently, into Virginia in a shipment of infected nursery saplings from Michigan. Officials destroyed the saplings as well as all a...

Hunger in America rises by 43 percent over last five years

... higher than the national average. The lone bright spot in the nation is Oregon. Once considered to have the worst hunger in the country, Oregon has shown significant decreases in food insecurity and hunger since 1999-2001. "With this astonishing level of food deprivation in America," Brown concluded, ...

UT Southwestern researchers discover master switch in cell death

... cancer. “We think this gene will really be a hot spot in research,?said Dr. Qing Zhong, postdoctoral researcher in biochemistry at UT Southwestern and lead author of a paper to be published in the July 1 issue of the journal Cell. The life and death of cells is a complex avalanche of reactions, control...

North & South American researchers find architectural abnormalities in T. cruzi ribosome

...NA that the parasite's ribosomes must process. The spot where the ribosome binds to the mRNA, for example, is roughly as far away from the turret and spire as the length of the 39-nucleotide leader sequence. "It could provide a unique scanning mechanism different from other eukaryotes," Frank said. "For ...

UW-Madison scientists zero in on drugs' sweet spots

...derpins them. The ability to zero in on the sweet spot of drugs derived from natural products promises to help scientists specify the role of the sugar and make new drugs or enhance old ones to greater precision and effect. The series of experiments performed by Thorson's team, for example, may help rese...

New law for resolution allows unprecedented sharpness in fluorescence microscopy

...the fact that light cannot be focused to a smaller spot due to diffraction. It seemed impossible to image ...a STED microscope, the relevant focal fluorescence spot can, in principle, be reduced in size to the size of a molecule (2-5 nm). This is due to the fact th...

Virulizin granted orphan drug status in Europe

...e nets are difficult for dolphins and porpoises to spot visually or detect with their sonar, so they may become tangled in the netting or in the ropes attached to the nets. "Almost 1,000 whales, dolphins and porpoises die every day in nets and fishing gear. Some species are being pushed to the brink of e...

Novel targets found for the development of drugs to complement, or replace, statins

...e nets are difficult for dolphins and porpoises to spot visually or detect with their sonar, so they may become tangled in the netting or in the ropes attached to the nets. "Almost 1,000 whales, dolphins and porpoises die every day in nets and fishing gear. Some species are being pushed to the brink of e...

Canada's first embryonic stem cell lines

...e nets are difficult for dolphins and porpoises to spot visually or detect with their sonar, so they may become tangled in the netting or in the ropes attached to the nets. "Almost 1,000 whales, dolphins and porpoises die every day in nets and fishing gear. Some species are being pushed to the brink of e...

Leading scientists rank endangered dolphins, porpoises most in need of immediate action

...e nets are difficult for dolphins and porpoises to spot visually or detect with their sonar, so they may become tangled in the netting or in the ropes attached to the nets. "Almost 1,000 whales, dolphins and porpoises die every day in nets and fishing gear. Some species are being pushed to the brink of e...

Nanowires can detect molecular signs of cancer, scientists find

Use of minuscule devices to spot cancer markers could lead to ultra-powerful new diagnostics Harvard University researchers have found that molecular markers indicating the presence of cancer in the body are readily detected in blood scanned by special arrays of silicon nanowires -...

For first time, brain cells generated in a dish

...ls mature along the way, finishing as neurons in a spot called the olfactory bulb. In the laboratory cult...the needed cell type and placing it in the correct spot would have major impact," said Dr. Eric Holland, a neurosurgeon at Memorial Sloan-Kettering Cancer C...

'Jumping genes' contribute to the uniqueness of individual brains

...em. Almost all of them are marooned at a permanent spot by mutations rendering them dysfunctional, but in humans a hundred or so are free to move via a "copy and paste" mechanism. Long dismissed as useless gibberish or "junk" DNA, the transposable L1 elements were thought to be intracellular parasites or ...

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