One gene links newborn neurons with those that die in diseases such as Alzheimer's
...e brains, areas where neurons are known to undergo spontaneous replacement. They found markedly low levels of UCHL1 in the replaceable neurons of both these regions. "Low levels of UCHL1 appear to be a feature of replaceable neurons wherever they occur," says Lombardino. The scientists also knew that, in songb...First frozen egg baby born in Canada
... age, a woman's fertility declines and the rate of spontaneous abortion increases significantly. The risks of chromosomal abnormalities, such as Down's syndrome, are also higher in babies produced by older women. Finally, current egg donor programs require matching the menstrual cycle of egg recipients; this pro......s well as the fact that Spoc-derived cells display spontaneous rhythmic beating and express cardiac markers, whether they are grown in a test tube or have migrated to injured hearts in study mice. The authors can't say why skeletal muscle would harbor cardiac stem cells, but for now, the Spoc cells provide a va...Hirsute Or Hairless? Two Proteins May Spell The Difference
...at hair follicles are expendable. The product of a spontaneous mutation that caught a cat breeder's eye, le chat nu, would quickly succumb in the wild—its winter coat consists of little more than a ridge of fur down the midback and tail—and needs special care to thrive as a pet. Hairless animals in the lab, on t...Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
...olyposis, or environmental stress that generates a spontaneous mutation in the APC gene, mutations in the Foxl1 gene or its targets may dramatically increase the likelihood that the second normal copy of the APC gene is lost or mutated, leading to the initiation of tumor formation. This study sets a new paradig......actively relaying a message, and the other through spontaneous release when the neuron is "at rest," or inactive.... neurotransmitter release ?one type of vesicle for spontaneous release, another vesicle associated with activity-dependent release. "These findings question one ...