UCI researchers discover key factor for survival of human embryonic stem cells
...on areas involving the nervous system, such as the spinal cord," Donovan said. "Neurotrophins help the growth of tissues in those areas and are commonly found in the nervous system. Therefore, when we use stem cells for therapy in those areas, we must be especially careful that no undifferentiated cells are...Cholesterol gets 'thumbs up' for role in digit development
...odified Sonic hedgehog in the developing brain and spinal cord. "We are finding some surprises,"Chiang said, "suggesting that the function of cholesterol is different in these different tissues."The continued study of the wide-ranging actions of Sonic hedgehog promises to expose the incredible secrets of ...NJIT engineer poised to take stem cell research a step forward
...on Spinal Cord Research, a state agency that funds spinal cord research. She will use the grant to build a l...the nerve cells in the body that control brain and spinal cord function -- patients with spinal cord injuries could be healed with injections of stem cells. ...Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal
...ral nervous system (CNS), comprising the brain and spinal cord, has been considered for a long time as "a forbidden city", in which the immune system is denied entry as its activity is perceived as a possible threat to the complex and dynamic nerve cell networks. Furthermore, immune cells that recognize the...A new focus for the mechanism of nerve growth
...erve growth, with particular interest in repair of spinal cord nerves after injury. ...Salk researchers make fast strides towards understanding how our body controls walking
...tudies have identified an important circuit in the spinal cord that controls the speed with which our leg mu...he main obstacles in developing new treatments for spinal cord injuries. "Knowing which circuits are important and understanding how they control the essenti...Blood flow in brain takes a twist, affecting views of Alzheimer's
...fingering astrocytes in diseases like epilepsy and spinal cord injury. "In a disease like Alzheimer's, for instance, perhaps it's the astrocytes themselves that are damaged first," she said. "It may be that for whatever reason, astrocytes are not doing their job properly, and then blood flow decreases. Thi...Chemical signaling helps regulate sensory map formation in the brain
... served to guide pathfinding axons up and down the spinal cord by attracting or repelling receptors on the growth cones of sensory or motor nerves. In this paper, Zou and colleagues reveal a new role for Wnts. They show that a gradient of Wnt3 along the medial-lateral axis within the developing brain is t...Loosen leash on cancer protein 'watchdog,' researchers say
...typically show - thinner skin, lower bone density, spinal hunching and the like," Mendrysa said. "We couldn't find any differences between them and normal mice. And their cancer rates were dramatically lower than expected, which turned out to be the more significant finding of the study." Mendrysa said the......nervous system (CNS) -- in the plasma and cerebral spinal fluid. One possible explanation for this glutamate build-up, reported online on March 6th in The Journal of Experimental Medicine, is a mutation in the gene encoding the glutamate transporter protein EAAT2. This mutation --- a single nucleotide cha...Possible brain hormone may unlock mystery of hibernation
...the putative hormone rose dramatically in cerebral spinal fluid, they reported. Likewise, HPc levels decreased abruptly in spinal fluid when hibernation terminated. The researchers also found that blocking the activity of one of ...With few factors, adult cells take on character of embryonic stem cells
...t a host of diseases, such as Parkinson's disease, spinal cord injury, and diabetes," said Shinya Yamanaka of Kyoto University in Japan. "However, there are ethical difficulties regarding the use of human embryos, as well as the problem of tissue rejection following transplantation into patients." Those p...NASA technology helping injured US troops
...ng U.S. soldiers returning from overseas duty with spinal cord or traumatic brain injuries, at Walter Reed A...ed who was wheelchair-bound for two years due to a spinal cord injury is now up and walking with SAM. "When we first put him in the walker, he was up and goin...Neurons grown from embryonic stem cells restore function in paralyzed rats
...f embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore...iques may be useful for treating such disorders as spinal cord injury, transverse myelitis, amyotrophic lateral sclerosis (ALS), and spinal muscular atrophy. ...Survivors of childhood polio do well decades later as they age
...es in 1979. The three major types of polio include spinal polio, a paralytic polio that attacks nerve cells in the spinal cord; bulbar polio, in which the virus attacks motor neurons in the brainstem; and bulbospinal polio...Spinal cord bridge bypasses injury to restore mobility
The body's spinal cord is like a super highway of nerves. When an i...versity of Arkansas bypassed this roadblock in the spinal cord. First, the researchers regenerated the severed nerve fibers, also called axons, around the ini...With few factors, adult cells take on character of embryonic stem cells
...t a host of diseases, such as Parkinson's disease, spinal cord injury, and diabetes," said Shinya Yamanaka of Kyoto University in Japan. "However, there are ethical difficulties regarding the use of human embryos, as well as the problem of tissue rejection following transplantation into patients." Those p...Flick of whiskers helps tease out brain's 'shadow' signaling system
...eir wastes, are central to diseases like epilepsy, spinal cord injury, and maybe even Alzheimer's disease. For decades scientists have studied the swift signaling activity of the brain's better-known cells, the neurons, by recording their electrical activity. But astrocytes don't fire in the same way, and ...New roles for growth factors: Enticing nerve cells to muscles
...ions may help restore movement in people following spinal cord injury, or those with motor neuron diseases such as Lou Gehrig's disease, spinal muscle atrophy, and post-polio syndrome. Failure to establish proper connectivity in the brain may a...Brain-computer link lets paralyzed patients convert thoughts into actions
...gle, a 25-year-old Massachusetts man with a severe spinal cord injury, has been paralyzed from the neck down...eting in June, David Chen, medical director of the spinal cord injury rehabilitation program at the Rehabilitation Institute of Chicago, presented preliminary...