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Tag: "spinal" at biology news

SuperLigands - a database of ligand structures derived from the Protein Data Bank

...females of various ages, suffering from disease or spinal cord injury. The research is being released by th...ale patients, ranging in age from 2 to 56, who had spinal cord injuries, juvenile diabetes and the genetic disease "congenital hypogamma-globulinemia." From ...

Molecular thermometers on skin cells detect heat and camphor

...n the sensory neurons that connect the skin to the spinal column and the brain. These proteins become activated when they receive the correct stimuli (such as a certain temperature), and this causes them to open and allow electrically charged ions to pass through and cause an electrical potential that signa...

Remote control flies? Fly behavior controlled by laser light

...ve been lost" due to injury or disease, such as in spinal cord trauma, although he notes that the possibility is "far-fetched" at the moment. The remote control is based on the idea that specific nerve cells could be equipped with molecular "receivers" that allow them to recognize an outside signal like a ...

Stem cell treatment improves mobility after spinal cord injury

...mbryonic stem cells improves mobility in rats with spinal cord injuries, providing the first physical eviden...ells can help restore motor skills lost from acute spinal cord tissue damage. Hans Keirstead and his colleagues in the Reeve-Irvine Research Center at UC Irv...

Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments

...ain hemispheres connected the central canal of the spinal cord. Zhou and his colleagues discovered how PK2 guides the migration of neurons born from neural stem cells from the subventricular zone in the brain's core through mature tissue to reach the olfactory bulb, the "smell" part of the brain located ab...

Combination therapy leads to partial recovery from spinal cord injury in rats

...ew "insulation" around nerve fibers in the damaged spinal cords of rats, a new study shows. The treatment, w...inding may eventually lead to new ways of treating spinal cord injury in humans. The study was funded in part by the National Institute of Neurological Disord...

Big differences in duplicated DNA distinguish chimp and human genomes

...mplicated in human developmental disorders such as spinal muscular atrophy and Prader-Willi syndrome. Parts of those duplicated segments have only single copies in the chimp genome, and it is possible that the chimpanzee is therefore not predisposed to the same diseases as a human. About two-thirds of huma...

New method shows it is possible to grow bone for grafts within a patient's body

... the broken bone. They use the same method to fuse spinal vertebrae to treat serious spinal injuries and back pain. Although this works well at the repair site, the removal operation is extrem...

Researchers grow stem cells from human skin

...ace damaged cells and tissue in conditions such as spinal cord injuries, diabetes, Alzheimer's disease, stroke and burns. Most scientists believe that stem cells from human embryos are the most versatile type of stem cell because they have the potential to form any cell or tissue in the body. But they are ...

Purdue scientists may have found key to halting spinal cord damage

...onsible for the tissue damage that follows initial spinal cord injury, a discovery that could also improve t..., a known carcinogen, is present at high levels in spinal tissue for several days after a traumatic injury. Although acrolein is produced by the body and is n...

Investigating 'brain shrinkage' in alcoholics

...egions and other neurons deep inside the brain and spinal cord. These nerve fibres make up white matter, which comprises the 'hard wiring' of the brain. Most of the fibres are insulated by a material called 'myelin' that is similar to the plastic coating around electrical wires. Nerve cells also have shorte...

3D Atlas Will Help Navigate The Spinal Cord

... prepare a three-dimensional (3D) atlas of the rat spinal cord over the next two years. Christopher Reeve m...ralia in 2003 and was impressed with their work in spinal injuries research. Professor Paxinos is a world leader in the preparation of brain atlases, being th...

UIC researchers show protein routes messages in nerve cells

...understand how nerves need to be reconnected after spinal cord injury, or may open doors to developing drugs that can manipulate proteins that cause neurological diseases in humans. ...

UQ researcher tracking key to healing the brain

...le played by stem cells in the mammalian brain and spinal cord under normal conditions and following injuries." He said at the moment, scientists rely on tissue culture methods to guess what is happening inside the body, but this new approach will mean they will be able to track the cells while they are w...

Researchers find molecule that inhibits regrowth of spinal nerve cells

...s to grow through myelin that is released when the spinal cord is damaged. While other myelin components als...ng to provide some sort of functional recovery for spinal cord injury patients, understanding ephrins is a major step forward," said Dr. Luis Parada, senior a...

Gradient guides nerve growth down spinal cord

...als that attracts developing sensory nerves up the spinal cord toward the brain serves to repel motor nerves...sicians restore function to people with paralyzing spinal cord injuries. Growing nerve cells send out axons, long narrow processes that search out and connec...

Scientists use gene transfer technology and common virus to block neuropathic pain in animals

...ed by the GAD gene moves to nerve terminals in the spinal cord where it triggers production of a powerful ne...sts have shown that decreased GABA activity in the spinal cord contributes to the development of neuropathic pain, according to Fink. Physicians have drugs t...

Scientists use gene transfer technology and common virus to block neuropathic pain

...ed by the GAD gene moves to nerve terminals in the spinal cord where it triggers production of a powerful ne...sts have shown that decreased GABA activity in the spinal cord contributes to the development of neuropathic pain, according to Fink. Physicians have drugs t...

Experimental shingles vaccine proves effective in nationwide study

...rs of sensory nerve cells usually located near the spinal cord, where the virus persists in a dormant state. As immunity weakens with advancing age, the virus can reactivate, multiply in and damage sensory nerve cells to cause pain. It then migrates to the skin, causing the blistering rash of shingles. Gen...

OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis

...t should have the capacity to repair the brain and spinal cord but they fail to do so. Our studies have reve...irth and damage to immature cells in the brain and spinal cord, called oligodendrocyte progenitors. These precursor cells give rise to all of the mature oligo...

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