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Tag: "spinal" at biology news

Wisconsin scientists grow critical nerve cells

...s have coaxed human embryonic stem cells to become spinal motor neurons, critical nervous system pathways th...Motor neurons transmit messages from the brain and spinal cord, dictating almost every movement in the body from the wiggling of a toe to the rolling of an ey...

Gene therapy converts dead bone graft to new, living tissue

... successful for the small bone transplants used in spinal fusion, but not for larger grafts, because the proteins' effectiveness wear off in just hours. By contrast, the gene therapy method triggers the tissue surrounding the graft to produce the proteins continuously for up to three weeks, long enough for ...

Researchers discover molecule that causes secondary stroke

...ng from the initial stroke. "Normally the cerebral spinal fluid that envelopes the brain carries off wastes ...ic stroke survivors are at greater risk." Several spinal fluid components were suspected of causing the vasospasm, Dr. Clark explains. They included hemoglob...

First real-time view of developing neurons reveals surprises, say Stanford researchers

...ny connections forming. What's more, any cure for spinal cord injuries will require new neurons to form the appropriate connections. ...

NJIT Presidential Award winner takes stem cell research another step

...d from bone marrow, umbilical cords, the brain and spinal cord and other tissues. Adult stem cells also have a unique trait that lends them their magic: Under the right conditions, or given the proper signals, they have the ability to turn into different cell types. Arinzeh is doing exactly that: developin...

Scientists discover that host cell lipids facilitate bacterial movement

...brain and the membranes that envelop the brain and spinal cord. Infection begins when the bacterium binds to a receptor on the surface of a cell, causing the cell to ingest it. The bacterium multiplies inside the cell and then uses a cellular protein called ActA to stimulate the host cell's actin to form fi...

Multiple Campylobacter Genomes Sequenced

...-Barré syndrome, in which the nerves that join the spinal cord and brain to the rest of the body are damaged, sometimes permanently. Campylobacteriosis is usually caused by C. jejuni, a spiral-shaped bacterium normally found in cattle, swine, and birds, where it causes no problems. But the illness can also...

Potential treatments for neurofibromatosis

...develop in the brain, on cranial nerves, or on the spinal cord. However, a rare form of the disease occurs ...erves, such as the sciatic nerve that connects the spinal cord with the leg and foot muscles. The tumors can interfere with the function of the brain and othe...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...d to revolutionary new treatments for Parkinson's, spinal cord injuries, Alzheimer's, cancer and other disea... healing neurological disorders, including stroke, spinal cord injury, brain tumors, multiple sclerosis and genetic diseases. Future studies will include inve...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...earchers analyzing fluid from around the brain and spinal cord have detected a protein linked in recent studies to Alzheimer's disease. Interesting application Read more about the bio-bar-code technology : - Gold nanoparticles and bio-bar codes bring sensitive DNA detection - Nanoparticle-Based Bio–Ba...

New component of the 'brakes' on nerve regeneration found

Among the principal obstacles to regenerating spinal cord and brain cells after injury is the "braking"...treatments to switch off the brakes on regrowth of spinal cord or brain tissue. The two groups--one group led by Jong Bae Park, Glenn Yiu, and colleagues fro...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...nce to reduce levels of mutant SOD1 protein in the spinal cords of transgenic ALS mice (mice bred to express the human SOD1 gene). Short strands of RNA that targeted multiple mutated and normal forms of the human SOD1 gene were delivered in a specially engineered lentivirus. Expression of the SOD1 protein w...

Test for early detection of prostate cancer shows promise

...ancer (two patients), kidney cancer (one patient), spinal cord injury (seven patients) and noncancerous prostate inflammation (two patients), and 16 healthy individuals. The study was conducted at the University of Pittsburgh while Getzenberg was a member of its faculty. The researchers found that EPCA lev...

Cerebral navigation: How do nerve fibers know what direction to grow in?

...opportunities for the development of therapies for spinal cord injury, targeting ephexin and possibly Vav," he speculates, "but much more needs to be known about how ephexin, Vav and other proteins work together to coordinate axon guidance." ...

Double triumph in stem cell quest

...2 to 56, with a variety of conditions ranging from spinal injuries to an inherited immune condition. The work proves that matching ESCs can be derived via therapeutic cloning from donors of any age and sex. "This is an enormous stride in the long journey to determine whether nuclear-transfer-derived human ...

Scientists discover that three overlapping signals in embryo help get the backbone right

... establishment of a back that morphs into a brain, spinal cord and muscles - turns out to be so important th...ssues that form on the back of the embryo - brain, spinal cord and muscles - were lost," Khokha said. "Not only were back tissues lost, but belly tissues were...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...ny part of the nervous system except the brain and spinal cord); abnormally high blood pressure; and proteinuria, a condition in which urine contains an abnormal amount of protein, than patients receiving paclitaxel alone. Other side effects were similar between the two treatment groups. Bevacizumab, a hum...

Stem cell research - new cell lines

...w treatments for diabetes, Parkinson's disease and spinal cord injury. "This cloning of cells involves a ne...ee embryonic layers ?one which forms the brain and spinal cord, another which forms the guts and liver and a third which forms muscles and bones," he said. "W...

Gene keeps neural cells on correct developmental path

...tem cell research aimed at understanding repairing spinal cord injuries or replacing malfunctioning brain cells in neurodegenerative diseases. It may also provide insights into other diseases, such as small cell lung cancer, which mistakenly make neuronal proteins, or neurological syndromes, where neuronal ...

Scientists generate patient-specific stem cells, Science study says

...females of various ages, suffering from disease or spinal cord injury. The research is being released by th...ale patients, ranging in age from 2 to 56, who had spinal cord injuries, juvenile diabetes and the genetic disease "congenital hypogamma-globulinemia." From ...

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