New RNAi tools enable systematic studies of gene function
...entists packaged them in lentiviruses. "Across the spectrum of biomedicine, there is a need for tools that can be applied to diverse cell types. This is particularly true in cancer research," said Bill Hahn, assistant professor at Dana-Farber Cancer Institute and Harvard Medical School, associate member of th...New nano-canary in the nanotoxicology coalmine: The body itself
...," said Weber. FTIR spectroscopy measures a broad spectrum of chemical bonds and will provide information that is complementary to genomic and proteomic approaches. FTIR spectra are captured in minutes in live cell studies, offering a tool to rapidly detect whether nanoparticles are biologically active. Th...Bocavirus infection may be associated with pneumonia in Thailand, especially in children
... LRTI. However, whether the virus causes LRTI, the spectrum of clinical illness, and the epidemiology of HBoV infections still need to be defined. Fry cautions, "We still do not know if the virus actually causes respiratory tract infections and we hope to get closer to the answer with our final analysis." Th...Rare Chinese frogs communicate by means of ultrasonic sound
...of the ways is to shift the frequencies beyond the spectrum of the background noise. Mammals such as bats, whales and dolphins do this, and use ultrasound for their sonar system and communication. Frogs were never taken into consideration for being able to do this." Adler had drawn attention to the species...Lizard 'third eye' sheds light on evolution of color vision
...the transitions of the day based on changes in the spectrum of sunlight," says Chih-Ying Su, Ph.D., the first author of the study and a former neuroscience graduate student at Hopkins. "It's just like in a small company," says Yau. "You have to delegate each person to do more things." By sharing features fo...Scientists re-engineer a well-known antibiotic to counter drug resistance
...all synthesis, significantly increasing the drug's spectrum of activity. In recent years, a number of the most common strains of enterococci have become resistant to vancomycin and use of the antibiotic has been under scrutiny. This re-engineering effort could help make the drug more effective in treating inf...BioMed Central launches Biology Direct
...es, and reviews and will eventually cover the full spectrum of biology. Biology Direct is led by Editors-in-Chief David J Lipman, Director of the National Center Biotechnology Information (NCBI) a division of the National Library of Medicine (NLM) at NIH, USA; Eugene V Koonin, Senior Investigator at NCBI; ...Biofuels can replace about 30 percent of fuel needs with significant research and policy effort
...k of biofuels, the group recommends a much broader spectrum of possible materials including agriculture wastes such as corn stovers and wheat stalks, fast-growing trees such as poplar and willow and several perennial energy crops such as switchgrass. In addition to including more diversity in materials, the ...Enzyme crystal structure reveals 'unexpected' genome repair functions
...ding damaged DNA during NER, which removes a broad spectrum of DNA lesions, including those caused by exposure to ultraviolet light." DNA needs constant repair because of the damage from a variety of sources that occurs to its base pairs of nucleotides. It is estimated that in every human cell more than 10,0...Plants used to detect gas leaks, from outer space!
...ellite remote systems to monitor gas leaks via the spectrum of reflected light from plants, which changes when the plants are stressed", says Steven. "A satellite image of the stress responses in vegetation should identify gas leaks at least as well as a visual report from a helicopter, which is the current ...Inflammation and drugs to control this activity studied in a variety of tumors sites
...in chemoprevention. "We need to look at a broader spectrum of conditions related to the inflammatory cascade and modulating the cascade with these and other compounds." Variants in the alpha-Methylacyl-CoA Racemase Gene and the Association with Advanced Distal Colorectal Adenomas in the Prostate, Lung, Col...Researches discover gene critical for protection against septic-shock-induced death
...rf2 is a pleiotropic protein thatregulates a broad spectrum of genes used by the host to defend against a variety of stresses, including oxidative and inflammatory diseases such as cigarette-smoke-induced emphysema and allergic asthma in mice models. Biswal's team found that the deletion of the Nrf2 gene in...Technique speeds up detecting, treating wound bacteria
...t is quite ill, clinicians necessarily use a broad spectrum (antibiotic), hoping not to overlook anything," Finegold said. "The resulting overuse of antibiotics definitely contributes to antibiotic resistance." According to the Centers for Disease Control and Prevention Web site, antibiotic resistance is a ...Heal thyself: Systems biology model reveals how cells avoid becoming cancerous
...opment of new therapeutic agents to combat a broad spectrum of diseases, including cancer, neurodegenerative diseases, and premature aging." Researchers involved in the study agreed that their findings could eventually be used to develop drugs to boost DNA repair in response to environmental toxins and possi...New findings offer more complete view of breast cancer gene mutations in US population
...d of carrying BRCA1 and BRCA2 mutations in a wider spectrum of women," said one of the study's lead investigators, Elaine Ostrander, Ph.D., chief of the Cancer Genetics Branch in the National Human Genome Research Institute's Division of Intramural Research. Dr. Ostrander was previously head of the genetics p...Study details hepatitis C ability to block immune system response
... interferon and how the virus can resist the broad spectrum of these antiviral effects." The knowledge gained from fundamental studies such as these could lay the groundwork for the development of potential new treatment strategies for this devastating global disease. ...New light microscope sharpens scientists' focus
...copic near-field microscopy, where we spread out a spectrum of light across wavelengths into lots of little glowing things. And that technique allowed us to see the individual constituents of a generalized glow." In fact, that "generalized glow" was much like what scientists see when they use a light microsco...New roles for growth factors: Enticing nerve cells to muscles
...connectivity in the brain may also underlie autism spectrum disorders and mental retardation. The multitasking members of the FGF growth factor family regulate blood vessel formation, wound repair, lung maturation, and development of skeletal muscle, blood and bone marrow cells. The Salk study adds on more j...New research: Soy germ isoflavones reduce bone loss
...oflavone concentrate, SoyLife® offers the complete spectrum of natural soy compounds, the Soy Matrix TM , which enhances the bio-availability of isoflavones. "In addition to this research, more studies are examining the effects of either soy or isoflavones on bone density in humans," said Mathern. "We are aw...Mice learn tasks that may help treat human psychiatric disorders
...4 per 1,000 children have autism or another autism spectrum disorder, making these disorders about as common as Type I juvenile diabetes. This rate is higher than for other childhood disabilities, including Down's syndrome, cancer, cerebral palsy, hearing loss and vision impairment. Although the number of c...