Gene Therapy For Parkinson's Disease Moves Forward In Animals
...showed the animals' dopamine systems were actually spared by the treatment. “The simplest question we're asking is, ‘Does any particular combination of proteins prevent or accelerate degeneration of the neurons?'?said Nicholas Muzyczka, Ph.D., an eminent scholar and professor of molecular genetics and micr...Gene therapy for Parkinson's disease moves forward in animals
...showed the animals' dopamine systems were actually spared by the treatment. "The simplest question we're asking is, 'Does any particular combination of proteins prevent or accelerate degeneration of the neurons?'" said Nicholas Muzyczka, Ph.D., an eminent scholar and professor of molecular genetics and mic...New Lab Research May Help Those Deafened By Immune System Attack
...kly if steroids could help them, or if they can be spared the drugs' harsh side effects. It may also expand the definition of the condition, known as autoimmune sensorineural hearing loss or AISNHL, and help more people get a firm diagnosis of what's causing their mysterious hearing loss. In the August iss...Gene therapy works in mice to prevent blindness that strikes boys
...that help the brain process light and color - were spared from the disease and the connections between the layers of the retinas were intact. In addition, the protein appears capable of moving within the retina to its target sites and the beneficial changes appear to be long lasting, researchers said. Espe......lcoholics with controls, that's not different in a spared area of the brain," Dr Dodd said. "In that way we can start to find those messages that show altered expression in the area of the brain that shows the pathology." He said the microarray analysis could be useful for many neurological diseases. ...Pain killer fights breast cancer by targeting key enzyme
... in other tissues that rely on the enzyme could be spared if a nimesulide analog was taken as a drug." He said that the next step is to study how the analogs affect other types of tissues to make sure that nimesulide's aromatase-inhibiting effects are truly isolated to breast tissue. "Then we need to con...Cloned stem cells prove identical to fertilized stem cells
...umber of stem cells in the blastocyst appear to be spared this faulty reprogramming. When stem cells from a cloned blastocyst are removed and placed into a dish, most die. A few, however, survive and give rise to an embryonic stem cell line, and these appear to be thoroughly reprogrammed. Researchers have...Mice lacking social memory molecule take bullying in stride
...erted an antidepressant-like effect; the mice were spared from developing social avoidance behavior following repeated social defeat. "Without BDNF in the circuit, an animal can't learn that a social stimulus is threatening and respond appropriately," explained Nestler. He and his colleagues also disc...Molecular force field helps cancer cells defend against attack
...cer cells from dividing and caused them to die but spared normal breast cells. "FAK is a critical molecule, and in the future different ways of targeting either the enzyme itself or targeting the binding between these various proteins will have a major impact on cancer, I believe," Cance said. "We think it...Today's babies are fatter babies
... July issue of Obesity. "The obesity epidemic has spared no age group, even our youngest children," says Matthew Gillman, MD, senior author of the study and associate professor in the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care). Over the cours...Gene signature assesses breast cancer outcomes
...ne signature can better identify who can safely be spared adjuvant chemotherapy in 6000 women with node-negative early-stage breast cancer. If validated, the tool could safely spare 1 in 6 women the burden of adjuvant chemotherapy. ...CSIRO imagery shows Outer Great Barrier Reef at risk from river plumes
...orth and never directly flow to the outer reef is spared the direct effects of such river floods. "A re-think is needed now that we know where flood plumes go," says CSIRO scientist Arnold Dekker, "and what this means as organic micropollutants may be travelling to parts of the reef scientists hadn't ...Are one-third of costly implanted heart devices unnecessary? New study suggests yes
...y of ICD candidates, as many as one-third could be spared the operation to implant a device, without raising...dden death. That would mean that Medicare could be spared the additional $90,000 lifetime cost of each device compared to best medical therapy. The study, ...Rapid response was crucial to containing the 1918 flu pandemic
...ty. Why were some municipalities such as St. Louis spared the fate of the hard-hit cities like Philadelphia when both implemented similar public health measures? What made the difference, according to two independent studies funded by the National Institutes of Health (NIH), was not only how but also how ra...