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Tag: "span" at biology news

A new mechanism of regulating RNA degradation

...scription, by moderating the activity and the life span of the RNA itself. One major pathway for such pos... that it plays a major role in regulating the life span of numerous RNAs, and thus controls gene activity. To better understand what controls the NMD syste...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...scription, by moderating the activity and the life span of the RNA itself. One major pathway for such pos... that it plays a major role in regulating the life span of numerous RNAs, and thus controls gene activity. To better understand what controls the NMD syste...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...osomes that play a key rolein controlling the life span of cells. With every cell division,telomeres get a bit shorter until eventually they become so short thatthe enzymes that copy DNA for cell division no longer work properly andthe cell stops dividing. In a sense, telomeres function as a kind ofcounti...

GATA: a graphic alignment tool for comparative sequence analysis

...osomes that play a key rolein controlling the life span of cells. With every cell division,telomeres get a bit shorter until eventually they become so short thatthe enzymes that copy DNA for cell division no longer work properly andthe cell stops dividing. In a sense, telomeres function as a kind ofcounti...

Research on Worms Yields Clues on Aging

...s had the unexpected effect of prolonging the life span of C.Elegans: A class of anti-seizure medications slows the rate of aging inroundworms, according to researchers at Washington University School ofMedicine in St. Louis. When exposed to drugs used to treat epilepsy inhumans, worms lived longer and re...

Nano-Probes Allow an Inside Look at Cell Nuclei

...ologists a ringside seat to nuclear processes that span several hours or days, such as DNA replication, genomic alterations, and cell cycle control. The long-lived probes may also allow researchers to track the effectiveness of disease-fighting drugs that target these processes. "We could determine wheth...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...atments are usually given every three weeks over a span of up to six months and can cause many unpleasant side effects, including nausea, hair loss and infections. Follicular lymphoma is the second most common type of non-Hodgkin's lymphoma and is not considered to be curable using these traditional trea...

Scientists find fossil proof of Egypt's ancient climate

...000 years ago. These particular snails have a life span of between one and two years, and build their shells in a classic spiral with whatever water is available that day. The snails were preserved in calcium carbonate deposits throughout the lake. "We're using the chemistry of the water over the course ...

Same-Sex Mating Discovered in a Toxic Fungus

... arranged contiguously, but which typically do not span an entire chromosome. C. neoformans exists in two mating types, a and alpha, determined by a single genetic region, or locus. Most fungal isolates taken from people infected by C. neoformans are of the alpha mating type, said study lead author and p...

Caloric restriction won't dramatically extend life span in humans: UCLA research

...ct their calories over their lifetimes, their life span increases by between 3 percent and 7 percent -- fa...elationship between how much you eat and your life span is not so dramatic, there are very real costs of being overweight -- including greater risk for hear...

Fluorescing lab worms signal longer life spans

... "We have shown it's possible to predict the life span in an organism on the first day of adult life base...sity laboratory. Most scientists believe the life span of humans and other living creatures is determined by a combination of genetic, environmental and ch...

Fragment of yellow fever virus may hold key to safer vaccine

...of Y-shaped antibodies against yellow fever likely span the pairs by grabbing the essential epitope on one and the supporting amino acids on the other, ter Meulen speculates. The findings may apply to the whole flavivirus family. The results confirm and extend similar studies in mice, but the human antib...

Carnegie Mellon University research reveals how cells process large genes

...elp investigators predict structures of genes that span large intervals of DNA, Lopez said. Recursive splicing relies on the unusual activity of a ratchetting point, a pattern of chemical groups (nucleotides) previously discovered within the genome by Lopez. One end of a ratchetting point contains a sequ...

Reversal of role for a viral protein associated with the development of lymphoma

...elp investigators predict structures of genes that span large intervals of DNA, Lopez said. Recursive splicing relies on the unusual activity of a ratchetting point, a pattern of chemical groups (nucleotides) previously discovered within the genome by Lopez. One end of a ratchetting point contains a sequ...

New clues to the dark side of a key anti-tumor guardian

...s the activity of normal p53--extended flies' life span and increased their ability to withstand gene-damaging stress. The authors found that this disruption of p53 did not further increase the lifespan of flies on a calorie-restricted diet, suggesting that decreased p53 activity and calorie restriction m...

Bigger brain size matters for intellectual ability

... brain size decreased with age in men over the age span of 25 to 80 years, but age hardly affected brain size in women. It is not known what protective factors, which could be genetic, hormonal or environmental, operate in women. It remains to be determined what the contribution of nature and nurture ar...

New technique multiplies life span in simple organisms

...ther. The result was a dramatically extended life span - up to six times longer than normal - when the SI...over-expression of the SIR2 gene could extend life span beyond its natural limit. However, Longo said, "We were convinced that SIR2 had the potential to be...

Same-sex mating by fungi spawned infection outbreak, evidence suggests

... arranged contiguously, but which typically do not span an entire chromosome. Cryptococcus exists in two mating types, "a" and "alpha," determined by a single genetic region, or locus. Earlier studies by the Duke team found that most Vancouver Island outbreak isolates are sexually fertile, but all are of...

Researchers solve mystery of how nuclear pores duplicate before cell division

...e explained. To form the transport channels that span the nuclear membrane, 30 different proteins, called nucleoporins, come together in an orderly fashion and insert themselves into the nuclear envelope, where they form eight-fold symmetrical nuclear pore complexes. Each protein is present in copies of...

Study finds evolution doesn't always favor bigger animals

... ostracodes that evolved over that 40 million year span were commensurate with the change expected given how much the ocean temperatures decreased over this time and how body sizes of living ostracodes vary with temperature. On average, for every degree centigrade of climatic cooling, each of the species ...

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