Common enzyme is a key player in DNA repair
...rgically excise and replace a faulty section. But sometimes a damaged bit of DNA slips through unrepaired. A faulty nucleotide--the basic constituent of DNA--can stall the temperamental DNA replication machinery as it unwinds and copies the genome in dividing cells. In humans, uncorrected DNA errors passed al...Sea coral's trick helps scientists tag proteins
...ny new GFP-like proteins in non-bioluminescent and sometimes even non-fluorescent marine organisms, Zimmer said. Meanwhile, Sergey Lukyanov and other researchers had discovered that certain wavelengths of light could cause striking spectral changes in some proteins, which could convert from dark to light or ...Lactic acid not athlete's poison, but an energy source - if you know how to use it
... separate from the oxygen-based oxidative pathway, sometimes called aerobic metabolism, used to burn lactate and other fuels in the body's tissues. Experiments with dead frogs in the 1920s seemed to show that lactate build-up eventually causes muscles to stop working. But Brooks in the 1980s and '90s showed t...Amazon rainforest greens up in the dry season
...e regimes in the tropics, including the fires that sometimes rage in tropical areas during El Nino years, which bring drought to many tropical areas, including the Amazon. The research team figured out when the intact forest grows by analyzing five years of satellite images from the MODIS (Moderate Resolution...UCSD biologists find new evidence for one-way evolution
...the harmful effects of inbreeding. This ability is sometimes lost, as is the case for garden tomatoes, which can set seed by self-fertilization. Apparently, once lost, the ability to reject pollen in order to prevent self-fertilization is never regained. Irreversible loss of complex traits, which result fro...Both alcoholism and chronic smoking can damage the brain's prefrontal cortex
...ms are so hard to use, and feel so unnatural, that sometimes people just don't use them. They put them on the closet shelf." How the Funding Will Work The initial two-year phase of the University of Utah's work will bring in up to $4.8 million. The second two-year phase could bring the total to $10.3 milli...University of Utah to help build bionic arm
...ms are so hard to use, and feel so unnatural, that sometimes people just don't use them. They put them on the closet shelf." How the Funding Will Work The initial two-year phase of the University of Utah's work will bring in up to $4.8 million. The second two-year phase could bring the total to $10.3 milli...Pittsburgh researchers discover that certain chemicals in the blood may indicate brain injury
...returned to a violent caretaker and be re-injured, sometimes with fatal consequences. Rachel Pardes Berger, MD, MPH, of Children's Child Advocacy Center, in collaboration with P. David Adelson, MD, of the Division of Pediatric Neurosurgery, and Patrick M. Kochanek, MD, of the Department of Pediatric Critical...Study finds drug may cut down involuntary movements
...untary, writhing movements of the limbs, face, and sometimes the entire body ?is the hallmark symptom of Huntington's disease, an inherited neurodegenerative disorder that worsens as brain cells known as medium spiny neurons are killed off by a mutant protein. The disease brings with it an array of other dif...MIT: Oceans are a major gene swap-meet for plankton
.... Such viruses, which carry genes of their own and sometimes transport odd genes picked up from an earlier host, are the most likely means of exchange - a natural way to get genes out of old cells and into new ones. In essence, what all this means is that "our image of ocean microbes and their role in planeta...Infused spleen cells found not to impact islet recovery and reversal of type 1 diabetes in mice
...A sequences that code for protein, non-coding DNA, sometimes referred to as "junk" DNA, follows few rules for organization and sequence patterns and therefore is more difficult to study. "The difficulty with human genetic approaches to common disease is that we lack the power to precisely localize DNA sequenc...Chemotherapy gel may fight breast cancer and reduce breast deformity
...urgery but that also would fill in the dimples and sometimes quite significant indentations that are common after breast surgery and radiation." To test their idea, the researchers encapsulated a common breast cancer chemotherapy drug, doxorubicin, in microspheres, or beads, and then mixed them with a gelatin...Junk DNA may not be so junky after all
...A sequences that code for protein, non-coding DNA, sometimes referred to as "junk" DNA, follows few rules for organization and sequence patterns and therefore is more difficult to study. "The difficulty with human genetic approaches to common disease is that we lack the power to precisely localize DNA sequenc...Ocean virus identified in human blood samples
... where it can replicate and recycle, infecting and sometimes causing health problems in seals, sea lions, whales, and perhaps fish, shellfish and other species. In general, the marine environment is "a relatively under-explored potential reservoir of human pathogens," the researchers said in their study. Hist......of the fight against cancer. But doctors know that sometimes these drugs effect a complete cure, while other times they can be nearly ineffective. How to turn some of those failures into successes? A team of scientists at the Weizmann Institute, headed by Prof. Hadassa Degani of the Biological Regulation Depar...Duck-billed dino crests not linked to sense of smell
...d loop over their skull. Duck-billed dinosaurs are sometimes referred to as the "Cows of the Cretaceous period" and lived 85 million to 65 million years ago. Evans reconstructed the dinosaurs' brain cavity using well-preserved fragments of fossilized bone and created the first-ever cast of the lambeosaur brai...Researchers create pigs that produce heart-healthy omega-3 fatty acids
...y among tumor cells might help explain why therapy sometimes fails. If a tumor contains a diverse population of cells, some of those cells are more likely to resist treatment, Maley says. Adapting to and surviving chemotherapy, these resistant cells could breed, leading to a cancer relapse. He hopes to pursue ...Evolutionary biology research techniques predict cancer
...y among tumor cells might help explain why therapy sometimes fails. If a tumor contains a diverse population of cells, some of those cells are more likely to resist treatment, Maley says. Adapting to and surviving chemotherapy, these resistant cells could breed, leading to a cancer relapse. He hopes to pursue ...Mining for gems in the fungal genome
...tabolites located just one compound at a time, and sometimes required prior knowledge about the compound of interest. Even after the genetic sequence of Aspergillus nidulans was completed in 2003, the search for secondary metabolites in that species continued. Although scientists were able to pinpoint the lo...... is known for its mace-like green fruit, which are sometimes called "gumballs." Now, this spiny fruit may become an important source of a chemical needed to make a lifesaving drug against bird flu ?a drug that is currently in short supply worldwide, researchers say. Chemists have found that the seeds of the s...