Hopkins scientists uncover 'tags' that force proteins to cell surface
...ould be on the cell surface isn't, and in the lab, sometimes it's proven impossible to get a protein to the cell surface in order to study it. The tags we've found might help us force proteins to the surface, which offers real hope for overcoming these hurdles." Laboratory studies in which the tags might be u...Defect in gene causes 'neuralgic amyotrophy'
...nt usually disappear within a couple of weeks, but sometimes recovery can take months or even several years. Ma...elid that covers the inside corner of the eye, and sometimes a cleft palate. HNA is a relatively rare disorder: the disease appears in some 200 families worldw...Mechanism regulating tooth shape formulation found
...eeth. Furthermore, these mice have extra teeth and sometimes adjacent teeth are fused. These results indicate that there is a delicate balance of induction and inhibition in determining tooth cusps and that ectodin is a key gene in this developmental control. The team confirmed the importasnce of ectodin to ...Discovery of T-cell 'traffic control' boosts new drug promise
...sues to fight infection -- a crucial response that sometimes goes awry, attacking the body's own tissues and causing autoimmune diseases. The traffic control system -- composed of a fat-like compound called S1P and its receptor on T cells -- usually prevents T cells from launching harmful reactions. But when ...Bacteria recognize antimicrobials, respond with counter-defenses
...ommon throughout the food chain. Learning how this sometimes deadly organism fights back against the immune system may lead to treatments that get around bacterial resistance. Work in this area may also suggest ways other disease-causing, Gram-negative bacteria maintain a stronghold in the midst of the body's...'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes
.... Although prior studies have shown that monkeys sometimes turn their head and eyes when they see another individual turn and look to the side, the study by Deaner and Platt provides the first evidence that monkeys reflexively and internally shift their attention where another individual is looking. The subj...Hybrid grass may prove to be valuable fuel source
...d fuel. The cool-weather-friendly perennial grass, sometimes referred to as elephant grass or E-grass, grows from an underground stem-like organ called a rhizome. Miscanthus, a crop native to Asia and a relative of sugarcane, drops its slender leaves in the winter, leaving behind tall bamboo-like stems that ca...Secrets to antibody's success against West Nile Virus surprise scientists
...ple with weakened immune systems and those over 50 sometimes lead to serious complications or death. Like West Nile, dengue virus is a flavivirus spread by mosquito bites, but only in tropical regions of the world. The dengue virus is estimated by Centers for Disease Control and Prevention epidemiologists to...Researchers uncover E. coli's defense mechanism
...organisms can cause diarrhea, abdominal cramps and sometimes more serious illnesses that require hospitalization. E.coli doesn't respond well to antibiotics, while Salmonella has developed several drug-resistant strains. Learning how the bacteria handle the body's immune response is the first step in developin...Plankton can run, but can't hide from basking sharks
... range of behaviours to try and avoid being eaten, sometimes staying at greater depths during the day and then feeding near the surface at night but at other times reversing this behaviour in an attempt to throw some of their predators (eg fish larvae and predatory invertebrates such as arrow worms) off their ...A virus-like hitchhiker may trigger bacterial meningitis
...e discovered how a normally harmless bacterium can sometimes trigger outbreaks of life-threatening meningitis. The human body harbors many harmless bacterial residents, known as commensals. One such bacterium, called Neisseria meningitidis, makes its home in the upper respiratory tract, usually without conseq...New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
...recognize the body's own tissues is essential, but sometimes the immune system loses the ability to distinguish "self" from potentially harmful invaders. This can lead to autoimmune disease characterized by destruction of healthy tissues. Although it is not clear exactly what causes the immune system to go awr...Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
... a constant depth with a precision of centimeters, sometimes in the face of strong vertical currents, is incredible," said Genin. "It implies that these organisms have extremely sensitive depth sensors, the nature of which is yet unknown. That depth-keeping behavior has evolved in so many different species imp...Genetic links could unlock clues to leading cause of blindness
...odel study subject. They're so similar, he said he sometimes slips images of rhesus monkey eyes into presentations for medical residents to see if anyone notices the difference. "I haven't been caught yet," he said. "Only the most expert would detect the differences." ...Scientists reveal how disease bacterium survives inside immune system cell
...However, staph bacteria can also cause serious and sometimes fatal infections, such as bloodstream infections, surgical wound infections and pneumonia. In their experiments, the research team compared the neutrophil response to A. phagocytophilum with that of a weak strain of S. aureus. Using microarray techn...Diabetic nerve therapy shows 'striking' results
...ome form of neuropathy that can cause numbness and sometimes pain and weakness in the hands, arms, feet and legs. Currently, patients are treated with painkillers and antidepressants that do not treat the underlying nerve damage. Progression to amputation is not inevitable but is always a threat. Problems ma...Any exposure to tobacco smoke during pregnancy is risky
...s largely discounted the effects of secondary ?and sometimes even direct exposure through maternal smoking ?or produced contradictory results. The original studies looked at mutation rates at the HPRT gene located on the X chromosome in cord blood samples from newborns. Dr. Grant's analysis pooled the studies...Survey reveals women and doctors aren't talking about HPV
...ystem. But in some cases, the infection persists - sometimes staying dormant in the body months or even years before it becomes active, with the potential to cause cell changes in the cervix that can ultimately become cancerous. The Pap test can identify cells that have become abnormal due to HPV, and HPV test...Alien woodwasp, threat to US pine trees, found in N.Y.
...frica, where it rarely is a pest, kills pines, and sometimes several other types of conifers, by introducing a toxic mucus and spores of a toxic fungus when the female lays her eggs through the bark and into the sapwood of the tree. "If S. noctilio is found to be established in New York or elsewhere in the U.......sing new, erosive channels to form. These channels sometimes undercut farm roads and fields, causing them to collapse. What's more, river rafters or thirsty wildlife and livestock often can't get through dense thickets of saltcedar bushes or stands of pink-blossomed trees. ...