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Tag: "slowed" at biology news

Mouse brain tumors mimic those in human genetic disorder

...ly equivalent to teenage years in humans,the cells slowed down to the same growth speed as astrocytes in controlmice."The fact that cell growth is dramatically reduced after a few monthsin mice and after a few years in humans tells us there may be growthsignals that are produced early in life, which are cri...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...ng researchers." If compounds could be found that slowed or halted cancer spread, doctors could gain valuable time in shrinking the primary tumor. "If we had the luxury of time, we could treat that primary tumor at lower doses, too, with fewer side effects for the patient," Dr. Huang said. Until now, agen...

Genetically modified natural killer immune cells attack, kill leukemia cells

... significant technical hurdles that have until now slowed development of NK-based therapies for ALL, according to Dario Campana, M.D., Ph.D., a member of St. Jude Hematology-Oncology and Pathology, and senior author of the Blood report. Progress in adapting NK cells to the treatment of ALL had been signific...

Gene vaccine for Alzheimer's disease shows promising results

...ithAlzheimer's disease, immunization with amyloids slowed the buildup ofplaque in the brain and appeared to slow cognitive loss."Although human clinical trials are still at least two years out,theoretically, we are on the right track," he said....

Scientists identify molecular events that drive cell senescence

...ithAlzheimer's disease, immunization with amyloids slowed the buildup ofplaque in the brain and appeared to slow cognitive loss."Although human clinical trials are still at least two years out,theoretically, we are on the right track," he said....

Scientists discover that host cell lipids facilitate bacterial movement

...he researchers also noticed that Listeria movement slowed down when the bacteria were treated with molecules that inhibited PI3-kinase, proving that Listeria depend on PI3-kinase to move. "Our studies show that Listeria is capable of inside-out signaling," explains Dr. Southwick. "Most signals arise from m...

HIV-1 spread through six transmission lines in the UK

...al growth in infection rates, the spread generally slowed in the early 1990s, more likely from changes in sexual behaviour than from reduced infectiousness resulting from antiretroviral therapy. The study by UCL, the Health Protection Agency and the University of Oxford statistically analysed the epidemic ...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

... significant technical hurdles that have until now slowed development of NK-based therapies for ALL, according to Dario Campana, M.D., Ph.D., a member of St. Jude Hematology-Oncology and Pathology, and senior author of the Blood report. Progress in adapting NK cells to the treatment of ALL had been signific...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...ge had remained unclear, he said. The researchers slowed DNA replication in yeast cells by reducing the availability of one form of DNA polymerase, which are enzymes critical in DNA duplication. Yeast with abnormally low levels of DNA polymerase exhibited higher frequencies of chromosomal loss and aberrati...

Low oxygen likely made Great Dying worse, greatly delayed recovery

...mentation likely increased the extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences of low oxygen levels during the late Permian period, but not about these biogeographical ones," he said. Atmospheric oxygen ...

Scientists reveal the shape of a protein that helps retroviruses break into cells

...mentation likely increased the extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences of low oxygen levels during the late Permian period, but not about these biogeographical ones," he said. Atmospheric oxygen ...

'Smart drug' targets deadly brain cancer

...nt for an incurable form of recurrent brain cancer slowed tumor growth in more than one-third of the 65 adult patients who tried it. The same research team also developed a screening technique to help predict which patients will respond best to this treatment. Mayo researchers will present these findings a...

Researchers create infectious hepatitis C virus in a test tube

...e hepatitis C virus life cycle in cell culture has slowed research progress on this important human pathogen," says senior author Charles M. Rice, Ph.D., Maurice R. and Corinne P. Greenberg Professor and head of the Laboratory of Virology and Infectious Disease at Rockefeller. "This system lays the foundat...

Neurotransmitters signal aggressive cancer, offer potential for early diagnosis

...ctions were revved up in the tumors and which were slowed down. The last piece of the puzzle was supplied by a highly sensitive instrument, called a mass spectrometer, that measured the products of cellular metabolism. The mass spectrometer measurements were cross-checked with the gene activity data and the...

Stem cells' electric abilities might help their safe clinical use

...ound that blocking potassium channels in ESCs also slowed their growth," says Li. "Our findings may lead to genetic strategies that suppress undesirable cell division after transplantation, not only for ESCs and their derivatives, but perhaps for adult stem cells as well." Li adds that much more work is ne...

NJIT study shows nanoparticles could damage plant life

...ows that nanoparticles of alumina (aluminum oxide) slowed the growth of roots in five species of plants -- corn, cucumber, cabbage, carrot and soybean. Alumina nanoparticles are commonly used in scratch-resistant transparent coatings, sunscreen lotions that provide transparent-UV protection and environmenta...

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds

...as a lot of potential to overcome issues that have slowed the field of gene therapy," Calos said. Calos said her approach has two advantages: one is that in her method the gene gets inserted directly into the cell's own DNA, which is why the correction is permanent. In some other methods the gene stays out...

Marathon of nano-sprinters

...s consequence is that the movement of the cargo is slowed down. In addition, the force felt by each pulling motor strongly increases the unbinding probability for such a motor. Furthermore, as more motors unbind, each of the remaining pulling motors has to sustain a larger force, which would mean that their...

Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects

...ily, the interferon signaling system's rate may be slowed because this helper protein interacts with Stat1 at less than the maximum amount," Holtzman says. "It's possible that the maximal setting would be harmful in the long term, because too much interferon could lead to inflammatory diseases. But we may f...

From one cell, many possible cures

...Up until now, however, stem cell research has been slowed by ethical controversy -- as well as by the rarity of the extraordinary cells themselves. That could be about to change: A Florida State University research team in Tallahassee, Fla. reports that it has designed a biomedical device that will allow s...

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