Survival of heart patients on beta-blockers varies greatly with genetic variation
...enerally effective. They are known to decrease the size of the infarct and seem to prolong survival, on av...dence of effect on survival, although small sample size makes this result uncertain. The beta-2 gene commonly has two points of sequence variation within t...New Lab Research May Help Those Deafened By Immune System Attack
...ent had positive Western blot results for the same size protein as is used in the commercial test. The two different blood tests weren't always consistent - - results were the same in 47 patients (both positive or both negative) but different in 16. But the IF test appeared give a more specific response ...Brain size may depend upon how neural cells are cleaved
...ers have discovered a novel way in which the brain size of developing mammals may be regulated. They have ...y play a powerful role in determining the ultimate size of the mammalian brain. Inherited disorders that cause the brain to develop too small or too large m...'Sinkers' provide missing piece in deep-sea puzzle
... seafloor. In other words, a patch of seafloor the size of a large dinner plate might receive carbon from about 100 sinkers over a year's time. To complete their study, the scientists also needed to know how much carbon each sinker transported to the seafloor. But first they had to collect some sinkers. ...Team of international scientists departs today to discover the unknown in China's Himalayan region
...cent of the Earth's surface, an area equivalent in size to Russia and Australia combined. New hotspot analysis shows that an estimated 50 percent of all vascular plants and 42 percent of terrestrial vertebrates exist only in these 34 hotspots. Results from the expedition will be shared with numerous enti...Hopkins scientists uncover 'tags' that force proteins to cell surface
...y not seem to be very important. But Li chose this size to study in part because naturally occurring proteins were already known to use similar-size bits for recognition and signaling. "The immune system uses ones that are seven to nine blocks long to identify viral proteins or other immune triggers," ex...Microbe has huge role in ocean life, carbon cycle
...holds that natural selection acts to reduce genome size because of the metabolic burden of replicating "junk" DNA with no adaptive value - SAR11 supports that theory. Researchers are particularly interested in SAR11, Giovannoni said, because of the critical role it plays in geochemistry. Photosynthesis i...Hormones and growth: The control of body size and developmental growth rate in fruit flies
...crease our understanding of how an organism's body size is determined and how the speed of its development...at there is a close linkage between the final body size of an organism and the length of its developmental stages: Elephants are larger and develop more slo...Why do aneurysms form? New studies suggest leading role for white blood cells
... two weeks, with an aneurysm area twice the normal size on average. In contrast, only 8 percent of the neutrophil-deficient mice developed an aneurysm and those that did develop were much smaller. The researchers also looked at the levels, activity and production of enzymes before and during the aneurysm...Naturally occurring asbestos linked to lung cancer
...rnia are reported to the registry. The registry's size enabled researchers to identify an association tha..., he said more must be learned about the types and size of fibers in asbestos deposits, the types of human activities that disturb asbestos fibers and the d...Ants, not evil spirits, create devil's gardens in the Amazon rainforest, study finds
...cated 10 devil's gardens for the study, ranging in size from one to 328 D.hirsuta plants. Two saplings of a common Amazonian tree called Cedrela odorata , or Spanish cedar, were planted inside each garden near the base of a D. hirsuta tree actively patrolled by worker ants. A sticky insect barrier w...Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
...s striking. Silencing BACE1 reduced the number and size of plaques by two thirds within a month, which is incredibly fast," says Singer. Co-authors of this work also include Edward Rockenstein and Leslie Crews, both at UCSD. Alzheimer's disease is a progressive neurodegenerative disorder and the most co...After the yeast is gone bacteria continue to develop flavor of sparkling wine
...ing wine quality in terms of aroma, flavor, bubble size and bubble persistence, especially for premium quality wines," says NĂºria Rius, a researcher on the study. The traditional Champenoise method of sparkling wine production requires addition of sucrose and yeast strains to the base wine for a second f...Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
...wn, are some of the oldest fossils with large body size and complex morphology. "Present in rocks ranging from 575 to 540 million years in age, these fossils provide the key to understand the prelude to the Cambrian Explosion when animals with skeletons and familiar morphologies began to bloom about 540-5...Nanoscale method for investigating living systems
...s. Their resistance to photobleaching and physical size of less than 10 nanometers are making them increasingly popular in biomedical applications ranging from intracellular tagging of molecules to applications such as tracking devices for neuronal receptors and as interfaces between nerve cells. Research...Weight control protein may yield antiobesity drugs
... their livers grew to more than twice their normal size owing to a massive accumulation of fat, Rui said. Moreover, the animals developed severely elevated blood sugar, insulin, and leptin concentrations. Elevated leptin levels are a hallmark of leptin resistance, a primary risk factor for obesity, he ad...Neanderthal teeth grew no faster than comparable modern humans'
...ildhood growth, during which brain matures both in size and through experiences. Some earlier hominids matured far more quickly than modern humans. "The question is when exactly did that pattern of development evolve in the growth of humans," she said. ...No small feat: First ever gene therapy success for muscular dystrophy achieved
...d laminin alpha-2 gene is not possible because its size makes it impossible for researchers to get it to squeeze inside viral vectors ?disarmed viruses that are used to shuttle genes into cells. But the team found a good stand-in in a similar protein called agrin that when miniaturized could be inserted i...Researchers discover how tumor suppressor gene works
...nies of cancer cells in culture, it diminished the size of many colonies, wiping out some of them. It also decreased the total number of cancer cells. The researchers have designed a very small protein that mimics the action of the natural p16 protein. "We hope this [small protein] will have anti-cancer...Methamphetamine Abuse, HIV Infection Cause Changes in Brain Structure
...HIV infection cause significant alterations in the size of certain brain structures, and in both cases the changes may be associated with impaired cognitive functions, such as difficulties in learning new information, solving problems, maintaining attention and quickly processing information. Co-occurring...