Macrophage signaling may affect hormone resistance in prostate tumors
...ne) contain within their structure a novel binding site not previously recognized by researchers, according to the study. This site makes these receptors uniquely responsive to inflammatory signals, because the protein that binds th...Sociality of sweat bees evolved simultaneously during climate change
...edit course in insect biology, and maintains a Web site on bee phylogeny, http://www.entomology.cornell.edu/BeePhylogeny/ , is also struck by the social flexibility of sweat bees. "Other social insects (such as ants, termites, paper wasps and honey bees) have reached 'a point of no return' in social ev...The giant protein titin helps build muscles
... X-ray beamlines at EMBL's Hamburg station, on the site of the German Electron Synchrotron Radiation Facility (DESY). From the extremely detailed image of the connections between the proteins they discovered that telethonin links the tails in a unique way that may give some clues to sarcomere assembly. T...Multi-million pound UK Biobank underway
...information is available on request (and via a web site www.ukbiobank.ac.uk), with a freephone number that volunteers and GPs can ring to raise any queries with a study team member. No one is pressured into taking part, and participants can withdraw at any time if they change their minds. The first assess...Avian influenza virus in mammals spreads beyond the site of infection to other organ systems
...asal, and rectal swabs, regardless of the original site of infection. Most interesting, virus spread throughout the organ systems with virus being found in respiratory and digestive tracts, liver, kidney, heart, brain, and lymph nodes. Furthermore, examination of infected tissues revealed cellular damage...Minor mutations in avian flu virus increase chances of human infection
...mall mutations can result in switching the binding site preference of the avian virus from receptors in the intestinal tract of birds to the respiratory tract of humans. These mutations, the study noted, were already "known in [some human influenza] viruses to increase binding for these receptors." The s...Front-line immune cells mature in four stages, study shows
Researchers here have cracked the site and the stages of development for the last major s...thymus and bone marrow, respectively. However, the site and stages of human NK cell development have eluded investigators until now. The findings advance ...Study in Science holds promise for a new approach to drug therapy
...controls. In one, white blood cells home in on the site of infection. The other involves pain relief broug...tes enzymes that allow the cells to home in on the site of infection. Researchers found that pre-treatment of white blood cells with M119 reduced activation...Honeybee decision-making ability rivals any department committee
...avity, they have a unique method of deciding which site is right: With great efficiency they narrow down t...'s a good choice, they also dance to advertise the site and revisit it frequently. Scouts committed to different sites compete to attract uncommitted scouts...Stem cell study for patients with heart attack damage seeks to regenerate heart muscle
... IV line. Other therapies require delivery to the site of the disease through catheterization or open surgical procedures, but this one is very simple and easy for the patient. "A person who has had a single, severe heart attack may survive but can be left with substantial damage to the heart muscle as ...Gene patterns in white blood cells quickly diagnose disease
... a day when hand-held devices could be used at the site of a suspected bioterrorism attack to determine who has been exposed within hours instead of days that would be required using traditional culture methods. "The technology is not there yet, but within 10 years this test could also be done in doct...Cholesterol gets 'thumbs up' for role in digit development
...lly develops into the pinkie finger or toe. At the site of its synthesis, Sonic hedgehog concentrations ar...why concentrations of the protein were high at the site of its production and then tapered off with increasing distance from the synthesis site. But previ...Both alcoholism and chronic smoking can damage the brain's prefrontal cortex
...ual limb. "The nerve is potentially an excellent site for communicating with the nervous system," Clark says. "It's like a private hotline to the muscle." He says a prototype of the bionic arm should be ready for testing in four years. It is not yet known if any Utah residents who lost arms will parti...The evolution of food plants: Genetic control of grass flower architecture
...n-bearing flowers) and the ear (female flowers and site of seed or kernel development). The tassel forms from the shoot apical meristem after the production of a defined number of leaves, whereas ears form at the tips of compact axillary branches. Normal maize ears are unbranched, and tassels have long br...University of Utah to help build bionic arm
...ual limb. "The nerve is potentially an excellent site for communicating with the nervous system," Clark says. "It's like a private hotline to the muscle." He says a prototype of the bionic arm should be ready for testing in four years. It is not yet known if any Utah residents who lost arms will parti...Sweet 'water taste' paradoxically predicts sweet taste inhibitors
...rs by binding to a second, low-affinity inhibitory site that causes the receptor to shift from an activated to an inhibitory state. When a water rinse removes sweet taste inhibitors from the inhibitory site, the sweet receptor is re-activated and the perception of sweetness returns. "The phenomenon of ...Diverse tropical forests defy metabolic ecology models
...lity data from repeated five-year censuses of this site proved so useful to ecologists and foresters alike that seventeen other tropical forests around the world adopted the same methodology. Now the consortium of universities and research organizations managing forest plots in South America, Africa, Indi...Nanotechnology may find disease before it starts
...c drugs that would act locally on a tissue, at the site of a tumor, and not have such a pronounced affect on the rest of the body," Rosol said. "The problem with chemotherapy is that the drug affects the whole body, causing a host of problems such as hair loss, diarrhea and anemia." ......ntral tegmental area (VTA), known to be a critical site of neural adaptation, or plasticity, induced by addictive drugs. However, it wasn't known whether orexin actually induced such plasticity. In experiments with rat brain slices, the researchers demonstrated that orexin A does increase activity of ne...