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Tag: "single" at biology news

Major gene study uncovers secrets of leukemia

...rs to investigate more than 350,000 markers called single nucleotide polymorphisms. Single nucleotide polymorphisms are individual variations in the DNA that are spaced across the human chromosomes. Single nucleotide polymorphisms function as flags for researchers, allowing them to detect specific deletions...

Nanotextured implant materials: blending in, not fighting back

...helial cells established themselves, they formed a single thin layer that inhibited overgrowth of the smooth muscle cells that tends to narrow stented arteries. In another experiment, published in the Journal of Biomedical Materials Research with Purdue graduate student Derick Miller, the team molded p...

Brown cancer biologists identify major player in cell growth

...skin and blood, and the creation of cancer -- is a single transcription factor called GABP, according to new research from The Warren Alpert Medical School of Brown University and Rhode Island Hospital. The work, published online in Nature Cell Biology, introduces a new pathway that can be manipulated to...

New details on how the immune system recognizes influenza

...ID awarded LIAI a $25 million contract to create a single repository of immune epitopes from critical diseas...e extensive database, which has become the largest single collection of such information anywhere in the world. It includes data from thousands of separate ar...

Woven scaffolds could improve cartilage repair

...rowth and then implant them into patients during a single procedure, the researchers said. "By taking a synthetic material that already has the properties of cartilage and combining it with living cells, we can build a human tissue that can be integrated rapidly into the body, representing a new approach...

It's OK for men with high blood pressure to have a drink or two, new study finds

...cted estimates of diet-disease associations in any single study are definitive." ...

Horse genome assembled

...mprised of 1 million signposts of variation called single nucleotide polymorphisms, or SNPs, will provide scientists with a genome-wide view of genetic variability in horses and help them identify the genetic contributions to physical and behavioral differences, as well as to disease susceptibility. There a...

LIAI completes world's most comprehensive analysis on influenza virus data

...r epitope had been used one time, for example by a single individual responding to a single virus, or 100 different times. Now, scientists can search the database and find out all existing in...

Scientists learn the origin of rogue B cells

...inst the theory that B cells should only express a single receptor," says Casellas. Using a technique in which they inserted a piece of human gene into the cells of laboratory mice, the researchers created a model for visualizing the process in live animals. "Most of what scientists do is to create syste...

Remote sheep population resists genetic drift

...population, bred over dozens of generations from a single male and female pair transplanted to Haute Island from a Parisian zoo, has maintained the genetic diversity of its founding parents. This finding challenges the widely accepted theory of genetic drift, which states the genetic diversity of an inbred ...

Soft-cell approach cuts animal tests

...ons between chemical exposure and toxic effects of single chemicals and chemical mixtures. ...

Nanotechnology meets biology and DNA finds its groove

...in solution, and there is no easy way to precisely single out individual molecules for study. Now, howeve...quick, inexpensive and efficient method to extract single DNA molecules and position them in nanoscale troughs or "slits," where they can be easily analyzed a...

Research finds music training 'tunes' human auditory system

...andarin, a tone language. In tone languages, a single word can differ in meaning depending on pitch patterns called "tones." For example, the Mandarin word "mi" delivered in a level tone means "to squint," in a rising tone means "to bewilder," and in a dipping (falling then rising) tone means "rice." E...

Gene elevating breast cancer risk also causes prostate cancer

...in several generations and all patients showed the single mutation in PALB2 that was studied. According to Winqvist, this suggests that this Finnish founder mutation may be important in heritable prostate cancer as well. Male breast cancer and colorectal cancer cases did not display the mutation. The con...

Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps

... complementary approaches and then combined into a single "melded assembly." In their analysis, scientists from 35 institutions compared this melded assembly to the reference sequence of the human genome, a newer unpublished draft sequence of the chimp genome, the sequence of more than a dozen other more di...

Chemo combination improves survival in asbestos-related cancer

...nced mesothelioma who were treated with either the single drug or the combination. "Pemetrexed used in combination with cisplatin significantly increases the length of survival, when compared with cisplatin alone," the researchers say. "Further research is needed into the optimum treatment regimen for pl...

Wired for sound: How the brain senses visual illusions

...rnal of Neuroscience. When subjects were shown a single flash of light interposed between two brief sounds, many subjects reported seeing two distinct flashes of light. Investigating the timing and location of the brain processes that underlie this illusory effect ?the illusion of seeing two flashes in t...

Angelman syndrome deficits rescued in mice

...at Angelman syndrome was caused by a mutation in a single gene, called UBE3A. They subsequently developed a mouse model of Angelman syndrome by mutating this gene. But the finding was baffling, said Weeber, because UBE3A is a "housekeeping" gene, meaning that it broadly regulates cellular processes not p...

Shedding new light on proteorhodopsin

...ing biofuels than microbes that can only utilize a single energy source. The results of this study appea...ison azide." The Berkeley researchers monitored single cells of E. coli and observed the response to light of the proton motive force (pmf), the electroche...

New study sheds light on 'dark states' in DNA

...ve probed an unusual high-energy state produced in single nucleotides -- the building blocks of DNA and RNA ... and uracil. The detection of this dark state in single bases in solution increases the chances that it may be found in the DNA double helix, said Bern Kohl...

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